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of 8
pro vyhledávání: '"Sherry Liang"'
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 3, p 798 (2020)
The β-blocker carvedilol prevents ultraviolet (UV)-induced skin cancer, but the mechanism is unknown. Since carvedilol possesses antioxidant activity, this study investigated whether carvedilol prevents oxidative photodamage of skin, a precursor eve
Externí odkaz:
https://doaj.org/article/5003f0ff19b24e89ac1f822b4b4550ea
Autor:
Kristan H. Cleveland, Abdullah Shamim, Sherry Liang, Ying Huang, Mengbing Chen, Cyrus Parsa, Bradley T. Andresen, Ayaz Shahid, Robert Orlando
Publikováno v:
Cancer Prev Res (Phila)
Skin cancer is the most common malignancy worldwide and is rapidly rising in incidence, representing a significant public health challenge. The β-blocker, carvedilol, has shown promising effects in preventing skin cancer. However, as a potent β-blo
Publikováno v:
International Journal of Molecular Sciences
Volume 21
Issue 3
International Journal of Molecular Sciences, Vol 21, Iss 3, p 798 (2020)
Volume 21
Issue 3
International Journal of Molecular Sciences, Vol 21, Iss 3, p 798 (2020)
The &beta
blocker carvedilol prevents ultraviolet (UV)-induced skin cancer, but the mechanism is unknown. Since carvedilol possesses antioxidant activity, this study investigated whether carvedilol prevents oxidative photodamage of skin, a precu
blocker carvedilol prevents ultraviolet (UV)-induced skin cancer, but the mechanism is unknown. Since carvedilol possesses antioxidant activity, this study investigated whether carvedilol prevents oxidative photodamage of skin, a precu
Autor:
Ying Huang, Steven Yeung, Kristan H. Cleveland, Kevin M. Huang, Sherry Liang, Bradley T. Andresen
Publikováno v:
Molecular Carcinogenesis. 57:997-1007
Recent studies suggest that the β-blocker drug carvedilol prevents skin carcinogenesis but the mechanism is unknown. Carvedilol is one of a few β-blockers identified as biased agonist based on an ability to promote β-arrestin-mediated processes su
Publikováno v:
The FASEB Journal. 32
Autor:
Ying Huang, Cyrus Parsa, Sherry Liang, Robert Orlando, Kevin M. Huang, Kristan H. Cleveland, Bradley T. Andresen, Etuajie Oiyemhonlan, Steven Yeung, Frank L. Meyskens
Publikováno v:
Huang, Kevin M; Liang, Sherry; Yeung, Steven; Oiyemhonlan, Etuajie; Cleveland, Kristan H; Parsa, Cyrus; et al.(2017). Topically Applied Carvedilol Attenuates Solar Ultraviolet Radiation Induced Skin Carcinogenesis.. Cancer prevention research (Philadelphia, Pa.), 10(10), 598-606. doi: 10.1158/1940-6207.capr-17-0132. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/9x959695
Huang, Kevin M; Liang, Sherry; Yeung, Steven; Oiyemhonlan, Etuajie; Cleveland, Kristan H; Parsa, Cyrus; et al.(2017). Topically Applied Carvedilol Attenuates Solar Ultraviolet Radiation Induced Skin Carcinogenesis.. Cancer prevention research (Philadelphia, Pa.), 10(10), 598-606. doi: 10.1158/1940-6207.capr-17-0132. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/5z67p1hp
Huang, Kevin M; Liang, Sherry; Yeung, Steven; Oiyemhonlan, Etuajie; Cleveland, Kristan H; Parsa, Cyrus; et al.(2017). Topically Applied Carvedilol Attenuates Solar Ultraviolet Radiation Induced Skin Carcinogenesis.. Cancer prevention research (Philadelphia, Pa.), 10(10), 598-606. doi: 10.1158/1940-6207.capr-17-0132. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/5z67p1hp
In previous studies, the β-blocker carvedilol inhibited EGF-induced epidermal cell transformation and chemical carcinogen-induced mouse skin hyperplasia. As exposure to ultraviolet (UV) radiation leads to skin cancer, the present study examined whet
Publikováno v:
Cancer Research. 79:5087-5087
Carvedilol is an FDA approved β-blocker traditionally prescribed for cardiovascular diseases. Our previous work demonstrated that carvedilol has preventive activity against ultraviolet radiation (UVR)-induced skin damage, inflammation, and carcinoge
Autor:
Andy Chang, Kristan H. Cleveland, Kevin M. Huang, Si Chen, Bradley T. Andresen, Ying Huang, Lei Guo, Sherry Liang
Publikováno v:
PLoS ONE
PLoS ONE, Vol 14, Iss 5, p e0217038 (2019)
PLoS ONE, Vol 14, Iss 5, p e0217038 (2019)
Carvedilol is reported to prevent cancers in humans and animal models. However, a molecular mechanism has yet to be established, and the extent to which other β-blockers are chemopreventive remains relatively unknown. A comparative pharmacological a