Zobrazeno 1 - 10
of 238
pro vyhledávání: '"Komuro, A."'
Autor:
Yuta Suzuki, Hidehiro Kaneko, Akira Okada, Satoshi Matsuoka, Hidetaka Itoh, Katsuhito Fujiu, Nobuaki Michihata, Taisuke Jo, Norifumi Takeda, Hiroyuki Morita, Satoko Yamaguchi, Koichi Node, Toshimasa Yamauchi, Hideo Yasunaga, Issei Komuro
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 107:1843-1853
Context The natural history of young adults with prediabetes and its association with cardiovascular health (CVH) metrics in progression to diabetes remain unknown. Objective We examined the association between CVH metrics and the annual incidence of
Autor:
Jian Wu, Cheng Yang, Jun Ren, Xiangdong Yang, Hiroshi Akazawa, Guoping Zhang, Chunjie Yang, Komuro Issei, Yunzeng Zou, Ning Zhou, Le Kang, Li Lin, Qi Wang, Xiaoyan Wang, Yunqin Chen, Ruizhen Chen, Junbo Ge, Hong Jiang, Aijun Sun, Hui Gong
Publikováno v:
Journal of Molecular and Cellular Cardiology. 162:110-118
It is well known that lectin-like oxidized low-density lipoprotein (ox-LDL) and its receptor LOX-1, angiotensin II (AngII) and its type 1 receptor (AT1-R) play an important role in the development of cardiac hypertrophy. However, the molecular mechan
Publikováno v:
Clinical Case Reports. 10
Marfan syndrome (MFS) an inherited disorder caused by FBN1 gene mutations, is well known to cause lethal aortic aneurysm and dissections at a relatively young age. Here, we report giant internal carotid artery aneurysms and porcelain aorta in an elde
Autor:
Yuko Yamanaka, Naoko Sawada, Issei Komuro, Takayuki Kawata, Yutaka Yatomi, Hiroyuki Morita, Megumi Hirokawa, Masao Daimon, Tomoko Nakao, Koichi Kimura, Boqing Xu
Publikováno v:
International Heart Journal. 62:95-103
Enlargement of the mitral valve (MV) has gained attention as a compensatory mechanism for functional mitral regurgitation (FMR). We aimed to determine if MV leaflet area is associated with MV coaptation-zone area and identify the clinical factors ass
Publikováno v:
International Heart Journal. 61:1294-1297
Porcelain aorta, defined as extensive calcification of the ascending aorta or aortic arch, is a reported risk factor for embolic stroke during cardiac surgery. However, the time course of the progression of aortic calcification leading to porcelain a
Autor:
Atsushi Mochida, Madoka Nakagawa, Junko Hyuga, Nobuhiko Tanabe, Yuko Fujita, Takeshi Satow, Taro Komuro, Satoshi Horiguchi
Publikováno v:
Neurocase. 26:368-371
A 48-year-old female suffered from cerebral infarction involving the left inferior frontal gyrus. This was due to ischemic complications of endovascular treatment for subarachnoid hemorrhage. She exhibited severe acalculia, agraphia, finger agnosia,
Autor:
Masamichi Ito, Toshikuni Sasaoka, Eiki Takimoto, Ichiro Manabe, Tomoaki Higo, Tomokazu Sumida, Toshiyuki Ko, Haruhiro Toko, Matthew R.G. Taylor, Atsushi Sanbe, Mary E. Sweet, Masahiro Satoh, Atsuhiko T. Naito, Seitaro Nomura, Issei Komuro, Kanna Fujita, Toshihiro Yamaguchi, Kenji Yoshimi
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-8 (2020)
Nature Communications
Nature Communications
Pathophysiological roles of cardiac dopamine system remain unknown. Here, we show the role of dopamine D1 receptor (D1R)-expressing cardiomyocytes (CMs) in triggering heart failure-associated ventricular arrhythmia. Comprehensive single-cell resoluti
Autor:
Yuta Suzuki, Hidehiro Kaneko, Akira Okada, Hidetaka Itoh, Kojiro Morita, Katsuhito Fujiu, Nobuaki Michihata, Taisuke Jo, Norifumi Takeda, Hiroyuki Morita, Satoko Yamaguchi, Kentaro Kamiya, Atsuhiko Matsunaga, Junya Ako, Akira Fukui, Akira Nishiyama, Takashi Yokoo, Koichi Node, Toshimasa Yamauchi, Masaomi Nangaku, Hideo Yasunaga, Issei Komuro
Publikováno v:
Am J Nephrol
Introduction: Evidence is lacking regarding the association between cardiovascular health (CVH) metrics and the risk for proteinuria. Methods: We performed this observational cohort study including 865,087 participants (median age, 46 years, 60.7% me
Autor:
Hiroshi Akazawa, Shogo Shimada, Issei Komuro, Hiroshi Kadowaki, Junichi Ishida, Masato Ishizuka, Minoru Ono, Arihiro Kiyosue, Masaru Hatano, Masae Uehara
Publikováno v:
International heart journal. 62(6)
Anti-HER2 therapy has greatly improved the long-term prognosis of patients with HER2-positive breast cancer. Meanwhile, by interfering with the protective effects of neuregulin-1/HER2 signaling on stressed cardiomyocytes, anti-HER2 therapy occasional
Autor:
Yoshiko Mizuno, Jumpei Ishiwata, Yuriko Yoshida, Megumi Hirokawa, Masao Daimon, Shunichi Homma, Hidehiro Kaneko, Issei Komuro, Hiroyuki Morita, Koki Nakanishi, Naoko Sawada, Tomoko Nakao, M. Di Tullio
Publikováno v:
Atherosclerosis. 305:42-49
Background Although carotid intima-media thickness (IMT) is an established marker of atherosclerosis and carries independent risk for cardiovascular disease, its possible association with subclinical cardiac dysfunction has not been extensively evalu