Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Craig J. Goergen"'
Autor:
Melissa M. Dann, Sydney Q. Clark, Natasha A. Trzaskalski, Conner C. Earl, Luke E. Schepers, Serena M. Pulente, Ebonee N. Lennord, Karthik Annamalai, Joseph M. Gruber, Abigail D. Cox, Ilka Lorenzen-Schmidt, Richard Seymour, Kyoung-Han Kim, Craig J. Goergen, Erin E. Mulvihill
Publikováno v:
Am J Physiol Heart Circ Physiol
Ischemic heart disease is the leading cause of death in the United States, Canada, and worldwide. Severe disease is characterized by coronary artery occlusion, loss of blood flow to the myocardium, and necrosis of tissue, with subsequent remodeling o
Autor:
Alycia G. Berman, Daniel J. Romary, Katherine E. Kerr, Natalyn E. Gorazd, Morgan M. Wigand, Sourav S. Patnaik, Ender A. Finol, Abigail D. Cox, Craig J. Goergen
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)
Scientific Reports
Scientific Reports
Abdominal aortic aneurysm (AAA) formation and expansion is highly complex and multifactorial, and the improvement of animal models is an important step to enhance our understanding of AAA pathophysiology. In this study, we explore our ability to infl
Autor:
Dar Weiss, Bruno V. Rego, Jay D. Humphrey, Alycia G. Berman, Marcos Latorre, Cristina Cavinato, B.J. Tanski, Craig J. Goergen
Publikováno v:
Acta Biomater
[EN] Abdominal aortic aneurysms (AAAs) are characterized histopathologically by compromised elastic fiber integrity, lost smooth muscle cells or their function, and remodeled collagen. We used a recently introduced mouse model of AAAs that combines e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10826468e3be0670da582692252ec27f
https://europepmc.org/articles/PMC8542633/
https://europepmc.org/articles/PMC8542633/
Autor:
Ender A. Finol, Craig J. Goergen, Shashank R. Sirsi, Kenneth Hoyt, Sourav S. Patnaik, Dan T. Simionescu
Publikováno v:
Annals of Biomedical Engineering. 47:39-59
Pentagalloyl glucose (PGG) is an elastin-stabilizing polyphenolic compound that has significant biomedical benefits, such as being a free radical sink, an anti-inflammatory agent, anti-diabetic agent, enzymatic resistant properties, etc. This review
Autor:
Elizabeth E. Niedert, Sourav S. Patnaik, Vangelina Osteguin, Renxiang Tang, Riley L Holloway, Ender A. Finol, Craig J. Goergen, Jennifer L. Anderson
Publikováno v:
Journal of Clinical Medicine
Volume 10
Issue 2
Journal of Clinical Medicine, Vol 10, Iss 219, p 219 (2021)
Volume 10
Issue 2
Journal of Clinical Medicine, Vol 10, Iss 219, p 219 (2021)
Abdominal aortic aneurysms (AAAs) are a local dilation of the aorta and are associated with significant mortality due to rupture and treatment complications. There is a need for less invasive treatments to prevent aneurysm growth and rupture. In this
Publikováno v:
Frontiers in Cardiovascular Medicine
Frontiers in Cardiovascular Medicine, Vol 7 (2020)
Frontiers in Cardiovascular Medicine, Vol 7 (2020)
Thoracic aortic aneurysm (TAA) is a focal enlargement of the thoracic aorta, but the etiology of this disease is not fully understood. Previous work suggests that various genetic syndromes, congenital defects such as bicuspid aortic valve, hypertensi
Publikováno v:
Am J Physiol Heart Circ Physiol
An abdominal aortic aneurysm (AAA), defined as a pathological expansion of the largest artery in the abdomen, is a common vascular disease that frequently leads to death if rupture occurs. Once diagnosed, clinicians typically evaluate the rupture ris
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea0b1c36d4a28d0d4ec981f69955bd1f
https://europepmc.org/articles/PMC6879923/
https://europepmc.org/articles/PMC6879923/
Publikováno v:
Journal of Biomechanical Engineering. 141
Current in vivo abdominal aortic aneurysm (AAA) imaging approaches tend to focus on maximum diameter but do not measure three-dimensional (3D) vascular deformation or strain. Complex vessel geometries, heterogeneous wall compositions, and surrounding
Autor:
Craig J. Goergen, Gurneet S Sangha, Matthias Trenner, Andrea Acuna, Lars Maegdefessel, Alycia G. Berman, Hans-Henning Eckstein, Albert Busch, Evan H. Phillips
Publikováno v:
J Vasc Res
Reduced lower-limb blood flow has been shown to lead to asymmetrical abdominal aortic aneurysms (AAAs) but the mechanism of action is not fully understood. Therefore, small animal ultrasound (Vevo2100, FUJIFILM VisualSonics) was used to longitudinall
Autor:
Paige E, Castle, Ulrich M, Scheven, A Colleen, Crouch, Amos A, Cao, Craig J, Goergen, Joan M, Greve
Publikováno v:
Journal of Magnetic Resonance Imaging
Background One of the primary biomechanical factors influencing arterial health is their deformation across the cardiac cycle, or cyclic strain, which is often associated with arterial stiffness. Deleterious changes in the cardiovascular system, e.g.