Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Tobias Pischon"'
Autor:
Daniela Weber, Tobias Pischon, Marta Stelmach-Mardas, Wolfgang Bernigau, Heiner Boeing, Manuela M. Bergmann, Raskit Lachmann
Publikováno v:
PLoS ONE, Vol 14, Iss 10, p e0223449 (2019)
PLoS ONE
PLoS ONE
The advancing age of the participants of the European Prospective Investigation into Cancer and Nutrition (EPIC)-Potsdam study was the incentive to investigate frailty as a major parameter of ageing. The aim of this study was to develop a multidimens
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b75d14e2cdabd55d2c259e40668f6ff
http://edoc.mdc-berlin.de/18478/7/18478suppl.zip
http://edoc.mdc-berlin.de/18478/7/18478suppl.zip
Autor:
Anna Floegel, Wolfgang Otto, Heiner Boeing, Tobias Pischon, Cornelia Weikert, Thomas Illig, Ulrike Rolle-Kampczyk, Jerzy Adamski, Tilman Kühn, Disorn Sookthai, Theron Johnson, Martin von Bergen, Cornelia Prehn, Rudolf Kaaks
Publikováno v:
European Journal of Epidemiology
European journal of epidemiology, 33(1): 55-66
Floegel, A, Kuhn, T, Sookthai, D, Johnson, T, Prehn, C, Rolle-Kampczyk, U, Otto, W, Weikert, C, Illig, T, von Bergen, M, Adamski, J, Boeing, H, Kaaks, R & Pischon, T 2018, ' Serum metabolites and risk of myocardial infarction and ischemic stroke: a targeted metabolomic approach in two German prospective cohorts ', European Journal of Epidemiology, vol. 33, no. 1, pp. 55-66 . https://doi.org/10.1007/s10654-017-0333-0
Floegel, A, Kühn, T, Sookthai, D, Johnson, T, Prehn, C, Rolle-Kampczyk, U, Otto, W, Weikert, C, Illig, T, von Bergen, M, Adamski, J, Boeing, H, Kaaks, R & Pischon, T 2018, ' Serum metabolites and risk of myocardial infarction and ischemic stroke : a targeted metabolomic approach in two German prospective cohorts ', European Journal of Epidemiology, vol. 33, no. 1, pp. 55-66 . https://doi.org/10.1007/s10654-017-0333-0
Eur. J. Epidemiol. 33, 55–66 (2018)
European journal of epidemiology, 33(1): 55-66
Floegel, A, Kuhn, T, Sookthai, D, Johnson, T, Prehn, C, Rolle-Kampczyk, U, Otto, W, Weikert, C, Illig, T, von Bergen, M, Adamski, J, Boeing, H, Kaaks, R & Pischon, T 2018, ' Serum metabolites and risk of myocardial infarction and ischemic stroke: a targeted metabolomic approach in two German prospective cohorts ', European Journal of Epidemiology, vol. 33, no. 1, pp. 55-66 . https://doi.org/10.1007/s10654-017-0333-0
Floegel, A, Kühn, T, Sookthai, D, Johnson, T, Prehn, C, Rolle-Kampczyk, U, Otto, W, Weikert, C, Illig, T, von Bergen, M, Adamski, J, Boeing, H, Kaaks, R & Pischon, T 2018, ' Serum metabolites and risk of myocardial infarction and ischemic stroke : a targeted metabolomic approach in two German prospective cohorts ', European Journal of Epidemiology, vol. 33, no. 1, pp. 55-66 . https://doi.org/10.1007/s10654-017-0333-0
Eur. J. Epidemiol. 33, 55–66 (2018)
Metabolomic approaches in prospective cohorts may offer a unique snapshot into early metabolic perturbations that are associated with a higher risk of cardiovascular diseases (CVD) in healthy people. We investigated the association of 105 serum metab
Autor:
Per Magne Ueland, Anne Tjønneland, Nicholas J. Wareham, Petra H.M. Peeters, Richard Palmqvist, Stein Emil Vollset, Marc J. Gunter, Kim Overvad, Miren Dorronsoro, Amanda J. Cross, Giovanna Masala, J. Ramón Quirós, Øivind Midttun, Krasimira Aleksandrova, Dimitrios Trichopoulos, Aurelio Barricarte, Yunxia Lu, Ruth C. Travis, Bas Bueno-de-Mesquita, Tilman Kuehn, Shu Chun Chuang, Claudia Agnoli, José María Huerta, Tobias Pischon, Martin Lajous, Heiner Boeing, Marie-Christine Boutron-Ruault, Pagona Lagiou, Antonia Trichopoulou, Guy Fagherazzi, Rosario Tumino, Rudolf Kaaks, Kay-Tee Khaw, Amalia Mattiello, Antonio Agudo, Esther Molina-Montes, Dagmar Drogan, Elisabete Weiderpass, Paolo Vineis, Elio Riboli, Ingrid Ljuslinder
Publikováno v:
Immunity and Ageing, 13. BioMed Central
Immunity & ageing : I & A, vol 13, iss 1
Chuang, S-C; Boeing, H; Vollset, SE; Midttun, Ø; Ueland, PM; Bueno-de-Mesquita, B; et al.(2016). Cellular immune activity biomarker neopterin is associated hyperlipidemia: results from a large population-based study.. Immunity & ageing : I & A, 13, 5. doi: 10.1186/s12979-016-0059-y. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/99g8x86j
Immunity & Ageing : I & A
Chuang, S-C, Boeing, H, Vollset, S E, Midttun, Ø, Ueland, P M, Bueno-de-Mesquita, B, Lajous, M, Fagherazzi, G, Boutron-Ruault, M-C, Kaaks, R, Küehn, T, Pischon, T, Drogan, D, Tjønneland, A, Overvad, K, Quirós, J R, Agudo, A, Molina-Montes, E, Dorronsoro, M, Huerta, J M, Barricarte, A, Khaw, K-T, Wareham, N J, Travis, R C, Trichopoulou, A, Lagiou, P, Trichopoulos, D, Masala, G, Agnoli, C, Tumino, R, Mattiello, A, Peeters, P H, Weiderpass, E, Palmqvist, R, Ljuslinder, I, Gunter, M, Lu, Y, Cross, A J, Riboli, E, Vineis, P & Aleksandrova, K 2016, ' Cellular immune activity biomarker neopterin is associated hyperlipidemia : results from a large population-based study ', Immunity & ageing : I & A, vol. 13, no. 5, pp. 5 . https://doi.org/10.1186/s12979-016-0059-y
Immunity & ageing, 13: 5
Chuang, S C, Boeing, H, Vollset, S E, Midttun, O, Ueland, P M, Bueno-de-Mesquita, B, Lajous, M, Fagherazzi, G, Boutron-Ruault, M C, Kaaks, R, Kuehn, T, Pischon, T, Drogan, D, Tjonneland, A, Overvad, K, Quiros, J R, Agudo, A, Molina-Montes, E, Dorronsoro, M, Huerta, J M, Barricarte, A, Khaw, K T, Wareham, N J, Travis, R C, Trichopoulou, A, Lagiou, P, Trichopoulos, D, Masala, G, Agnoli, C, Tumino, R, Mattiello, A, Peeters, P H, Weiderpass, E, Palmqvist, R, Ljuslinder, I, Gunter, M, Cross, A J, Riboli, E, Vineis, P & Aleksandrova, K 2016, ' Cellular immune activity biomarker neopterin is associated hyperlipidemia: results from a large population-based study ', Immunity and Ageing . https://doi.org/10.1186/s12979-016-0059-y
Dipòsit Digital de la UB
Universidad de Barcelona
Recercat. Dipósit de la Recerca de Catalunya
instname
Immunity & ageing : I & A, vol 13, iss 1
Chuang, S-C; Boeing, H; Vollset, SE; Midttun, Ø; Ueland, PM; Bueno-de-Mesquita, B; et al.(2016). Cellular immune activity biomarker neopterin is associated hyperlipidemia: results from a large population-based study.. Immunity & ageing : I & A, 13, 5. doi: 10.1186/s12979-016-0059-y. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/99g8x86j
Immunity & Ageing : I & A
Chuang, S-C, Boeing, H, Vollset, S E, Midttun, Ø, Ueland, P M, Bueno-de-Mesquita, B, Lajous, M, Fagherazzi, G, Boutron-Ruault, M-C, Kaaks, R, Küehn, T, Pischon, T, Drogan, D, Tjønneland, A, Overvad, K, Quirós, J R, Agudo, A, Molina-Montes, E, Dorronsoro, M, Huerta, J M, Barricarte, A, Khaw, K-T, Wareham, N J, Travis, R C, Trichopoulou, A, Lagiou, P, Trichopoulos, D, Masala, G, Agnoli, C, Tumino, R, Mattiello, A, Peeters, P H, Weiderpass, E, Palmqvist, R, Ljuslinder, I, Gunter, M, Lu, Y, Cross, A J, Riboli, E, Vineis, P & Aleksandrova, K 2016, ' Cellular immune activity biomarker neopterin is associated hyperlipidemia : results from a large population-based study ', Immunity & ageing : I & A, vol. 13, no. 5, pp. 5 . https://doi.org/10.1186/s12979-016-0059-y
Immunity & ageing, 13: 5
Chuang, S C, Boeing, H, Vollset, S E, Midttun, O, Ueland, P M, Bueno-de-Mesquita, B, Lajous, M, Fagherazzi, G, Boutron-Ruault, M C, Kaaks, R, Kuehn, T, Pischon, T, Drogan, D, Tjonneland, A, Overvad, K, Quiros, J R, Agudo, A, Molina-Montes, E, Dorronsoro, M, Huerta, J M, Barricarte, A, Khaw, K T, Wareham, N J, Travis, R C, Trichopoulou, A, Lagiou, P, Trichopoulos, D, Masala, G, Agnoli, C, Tumino, R, Mattiello, A, Peeters, P H, Weiderpass, E, Palmqvist, R, Ljuslinder, I, Gunter, M, Cross, A J, Riboli, E, Vineis, P & Aleksandrova, K 2016, ' Cellular immune activity biomarker neopterin is associated hyperlipidemia: results from a large population-based study ', Immunity and Ageing . https://doi.org/10.1186/s12979-016-0059-y
Dipòsit Digital de la UB
Universidad de Barcelona
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instname
BACKGROUND: Increased serum neopterin had been described in older age two decades ago. Neopterin is a biomarker of systemic adaptive immune activation that could be potentially implicated in metabolic syndrome (MetS). Measurements of waist circumfere
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f322b52d6051918d0e1b817bd9d9423
http://hdl.handle.net/11250/2393605
http://hdl.handle.net/11250/2393605
Autor:
Andreas Fritsche, Cornelia Weikert, Tobias Pischon, Krasimira Aleksandrova, Matthias B. Schulze, Berend Isermann, Heiner Boeing, Clemens Wittenbecher, Romina di Giuseppe, Juliane Menzel, Ronald Biemann
Publikováno v:
Atherosclerosis, 251: 415-421
BACKGROUND AND AIMS: The recently identified adipokine omentin-1 is inversely associated with body fatness, metabolic syndrome and cardiovascular disease (CVD) in cross-sectional analyses. However, prospective data on the association between plasma o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd09af72582dd0e780201f1cf5f20c71
http://www.sciencedirect.com/science/article/pii/S002191501630243X?via=ihub#appsec1
http://www.sciencedirect.com/science/article/pii/S002191501630243X?via=ihub#appsec1
Autor:
Rainer Lehmann, Matthias B. Schulze, Heiner Boeing, Jukka Montonen, Andreas Fritsche, Tobias Pischon, H. G. Joost, Annika Steffen
Publikováno v:
Diabetologia
AIMS/HYPOTHESIS: The aim of this study was to prospectively examine the association between body iron stores and risk of type 2 diabetes. METHODS: We designed a case-cohort study among 27,548 individuals within the population-based European Prospecti
Autor:
Domenico Palli, Aurelio Barricarte, José Ramón Quirós, Laureen Dartois, Heather Ward, Salvatore Panico, Isabelle Romieu, Veronika Fedirko, Ulrika Ericson, Kim Overvad, Miren Dorronsoro, Pagona Lagiou, Krasimira Aleksandrova, Rudolf Kaaks, Kay-Tee Khaw, Anne Tjønneland, Elio Riboli, Laure Dossus, Sabina Rinaldi, Ingrid Ljuslinder, Genevieve Buckland, Marc J. Gunter, Petra H.M. Peeters, Vittorio Krogh, Alessio Naccarati, Ingegerd Johansson, Bodil Ohlsson, Peter D. Siersema, Kathryn E. Bradbury, Heiner Boeing, María José Sánchez, Mazda Jenab, Antonia Trichopoulou, H. Bas Bueno-de-Mesquita, Elisabete Weiderpass, Guri Skeie, Kristin Benjaminsen Borch, Tobias Pischon, Sven Knüppel, Teresa Norat, Nicholas J. Wareham, Joyce Kong, Dora Romaguera, Kuanrong Li, Dimitrios Trichopoulos, Rosario Tumino, Marie-Christine Boutron-Ruault, María Dolores Chirlaque
Publikováno v:
BMC Medicine
BMC Medicine; 12, no 168 (2014)
Dipòsit Digital de la UB
Universidad de Barcelona
Recercat. Dipósit de la Recerca de Catalunya
instname
BMC medicine, 12: 168
Aleksandrova, K, Pischon, T, Jenab, M, Bueno-de-Mesquita, H, Fedirko, V, Norat, T, Romaguera, D, Knüppel, S, Boutron-Ruault, M-C, Dossus, L, Dartois, L, Kaaks, R, Li, K, Tjønneland, A, Overvad, K, Quirós, J, Buckland, G, Sánchez, M, Dorronsoro, M, Chirlaque, M-D, Barricarte, A, Khaw, K-T, Wareham, N J, Bradbury, K E, Trichopoulou, A, Lagiou, P, Trichopoulos, D, Palli, D, Krogh, V, Tumino, R, Naccarati, A, Panico, S, Siersema, P D, Peeters, P, Ljuslinder, I, Johansson, I, Ericson, U, Ohlsson, B, Weiderpass, E, Skeie, G, Borch, K, Rinaldi, S, Romieu, I, Kong, J, Gunter, M J, Ward, H A, Riboli, E & Boeing, H 2014, ' Combined impact of healthy lifestyle factors on colorectal cancer : a large European cohort study ', B M C Medicine, vol. 12, no. 1, pp. 168 . https://doi.org/10.1186/s12916-014-0168-4
BMC Medicine; 12, no 168 (2014)
Dipòsit Digital de la UB
Universidad de Barcelona
Recercat. Dipósit de la Recerca de Catalunya
instname
BMC medicine, 12: 168
Aleksandrova, K, Pischon, T, Jenab, M, Bueno-de-Mesquita, H, Fedirko, V, Norat, T, Romaguera, D, Knüppel, S, Boutron-Ruault, M-C, Dossus, L, Dartois, L, Kaaks, R, Li, K, Tjønneland, A, Overvad, K, Quirós, J, Buckland, G, Sánchez, M, Dorronsoro, M, Chirlaque, M-D, Barricarte, A, Khaw, K-T, Wareham, N J, Bradbury, K E, Trichopoulou, A, Lagiou, P, Trichopoulos, D, Palli, D, Krogh, V, Tumino, R, Naccarati, A, Panico, S, Siersema, P D, Peeters, P, Ljuslinder, I, Johansson, I, Ericson, U, Ohlsson, B, Weiderpass, E, Skeie, G, Borch, K, Rinaldi, S, Romieu, I, Kong, J, Gunter, M J, Ward, H A, Riboli, E & Boeing, H 2014, ' Combined impact of healthy lifestyle factors on colorectal cancer : a large European cohort study ', B M C Medicine, vol. 12, no. 1, pp. 168 . https://doi.org/10.1186/s12916-014-0168-4
Background: Excess body weight, physical activity, smoking, alcohol consumption and certain dietary factors are individually related to colorectal cancer (CRC) risk; however, little is known about their joint effects. The aim of this study was to dev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c2df47cf30eb37a9e8c200be1546798
http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-95215
http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-95215
Autor:
Laudina Rodríguez, Anika Hüsing, Isabelle Romieu, Rudolf Kaaks, Naomi E. Allen, Heiner Boeing, Federico Canzian, Carlotta Sacerdote, Kim Overvad, Núria Sala, David G. Cox, Elio Riboli, José María Huerta, Henk J. van Kranen, Lucie Dostal, H. Bas Bueno-de-Mesquita, Jane Nautrup Østergaard, Afshan Siddiq, Ruth C. Travis, María José Sánchez, Nerea Larrañaga, Anne Tjønneland, Angelika Stein, Göran Hallmans, Nicholas J. Wareham, Daniele Campa, Antonia Trichopoulou, Nina Roswall, Rosario Tumino, Pagona Lagiou, Mazda Jenab, Dimitrios Trichopoulos, Aurelio Barricarte, Mattias Johansson, Kay-Tee Khaw, Domenico Palli, Tobias Pischon, Sabina Sieri
Publikováno v:
PLoS ONE
PLoS ONE, Public Library of Science, 2011, 6 (2), pp.e16914. ⟨10.1371/journal.pone.0016914⟩
Campa, D, Hüsing, A, Stein, A, Dostal, L, Boeing, H, Pischon, T, Tjønneland, A, Roswall, N, Overvad, K, Østergaard, J N, Rodríguez, L, Sala, N, Sánchez, M-J, Larrañaga, N, Huerta, J M, Barricarte, A, Khaw, K-T, Wareham, N, Travis, R C, Allen, N E, Lagiou, P, Trichopoulou, A, Trichopoulos, D, Palli, D, Sieri, S, Tumino, R, Sacerdote, C, van Kranen, H, Bueno-de-Mesquita, H B, Hallmans, G, Johansson, M, Romieu, I, Jenab, M, Cox, D G, Siddiq, A, Riboli, E, Canzian, F & Kaaks, R 2011, ' Genetic Variability of the mTOR Pathway and Prostate Cancer Risk in the European Prospective Investigation on Cancer (EPIC) ', P L o S One, vol. 6, no. 2, pp. e16914 . https://doi.org/10.1371/journal.pone.0016914
PLoS ONE, Public Library of Science, 2011, 6 (2), pp.e16914. 〈10.1371/journal.pone.0016914〉
Dipòsit Digital de la UB
Universidad de Barcelona
PLoS ONE, Vol 6, Iss 2, p e16914 (2011)
Recercat. Dipósit de la Recerca de Catalunya
instname
PLoS ONE, Public Library of Science, 2011, 6 (2), pp.e16914. ⟨10.1371/journal.pone.0016914⟩
Campa, D, Hüsing, A, Stein, A, Dostal, L, Boeing, H, Pischon, T, Tjønneland, A, Roswall, N, Overvad, K, Østergaard, J N, Rodríguez, L, Sala, N, Sánchez, M-J, Larrañaga, N, Huerta, J M, Barricarte, A, Khaw, K-T, Wareham, N, Travis, R C, Allen, N E, Lagiou, P, Trichopoulou, A, Trichopoulos, D, Palli, D, Sieri, S, Tumino, R, Sacerdote, C, van Kranen, H, Bueno-de-Mesquita, H B, Hallmans, G, Johansson, M, Romieu, I, Jenab, M, Cox, D G, Siddiq, A, Riboli, E, Canzian, F & Kaaks, R 2011, ' Genetic Variability of the mTOR Pathway and Prostate Cancer Risk in the European Prospective Investigation on Cancer (EPIC) ', P L o S One, vol. 6, no. 2, pp. e16914 . https://doi.org/10.1371/journal.pone.0016914
PLoS ONE, Public Library of Science, 2011, 6 (2), pp.e16914. 〈10.1371/journal.pone.0016914〉
Dipòsit Digital de la UB
Universidad de Barcelona
PLoS ONE, Vol 6, Iss 2, p e16914 (2011)
Recercat. Dipósit de la Recerca de Catalunya
instname
International audience; The mTOR (mammalian target of rapamycin) signal transduction pathway integrates various signals, regulating ribosome biogenesis and protein synthesis as a function of available energy and amino acids, and assuring an appropria
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c55135331fb7c7ac6f04ea0f4de4500
https://hdl.handle.net/10668/253
https://hdl.handle.net/10668/253
Autor:
Antonio Agudo, Carla H. van Gils, Naomi E. Allen, Miren Dorronsoro, Tobias Pischon, Christina C. Dahm, Antonia Trichopoulou, Madlen Schütze, Sabine Rohrmann, Tara Kehoe, Nadia Slimani, Nicholas J. Wareham, Aurelio Barricarte, Paolo Boffetta, Kim Overvad, Rudolf Kaaks, Petra H.M. Peeters, María José Sánchez, Jürgen Rehm, Anja Olsen, Gerrit Gmel, Laudina Rodríguez, Manuela M. Bergmann, Françoise Clavel-Chapelon, Heiner Boeing, Franco Berrino, Petra A. Wark, Mazda Jenab, Elio Riboli, María Dolores Chirlaque, Vasiliki Benetou, Anne Tjønneland, Dora Romaguera, Kay-Tee Khaw, Rosario Tumino, Paolo Vineis, Marie-Christine Boutron-Ruault, Dimosthenis Zylis, Domenico Palli, Timothy J. Key
Publikováno v:
Scopus-Elsevier
The BMJ
Schütze, M, Boeing, H, Pischon, T, Rehm, J, Kehoe, T, Gmel, G, Olsen, A, Tjønneland, A M, Dahm, C C, Overvad, K, Clavel-Chapelon, F, Boutron-Ruault, M-C, Trichopoulou, A, Benetou, V, Zylis, D, Kaaks, R, Rohrmann, S, Palli, D, Berrino, F, Tumino, R, Vineis, P, Rodríguez, L, Agudo, A, Sánchez, M-J, Dorronsoro, M, Chirlaque, M-D, Barricarte, A, Peeters, P H, van Gils, C H, Khaw, K-T, Wareham, N, Allen, N E, Key, T J, Boffetta, P, Slimani, N, Jenab, M, Romaguera, D, Wark, P A, Riboli, E & Bergmann, M M 2011, ' Alcohol attributable burden of incidence of cancer in eight European countries based on results from prospective cohort study ', B M J (Clinical Research Edition), vol. 342, pp. d1584 . https://doi.org/10.1136/bmj.d1584
The BMJ
Schütze, M, Boeing, H, Pischon, T, Rehm, J, Kehoe, T, Gmel, G, Olsen, A, Tjønneland, A M, Dahm, C C, Overvad, K, Clavel-Chapelon, F, Boutron-Ruault, M-C, Trichopoulou, A, Benetou, V, Zylis, D, Kaaks, R, Rohrmann, S, Palli, D, Berrino, F, Tumino, R, Vineis, P, Rodríguez, L, Agudo, A, Sánchez, M-J, Dorronsoro, M, Chirlaque, M-D, Barricarte, A, Peeters, P H, van Gils, C H, Khaw, K-T, Wareham, N, Allen, N E, Key, T J, Boffetta, P, Slimani, N, Jenab, M, Romaguera, D, Wark, P A, Riboli, E & Bergmann, M M 2011, ' Alcohol attributable burden of incidence of cancer in eight European countries based on results from prospective cohort study ', B M J (Clinical Research Edition), vol. 342, pp. d1584 . https://doi.org/10.1136/bmj.d1584
Objective To compute the burden of cancer attributable to current and former alcohol consumption in eight European countries based on direct relative risk estimates from a cohort study. Design Combination of prospective cohort study with representati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d343effa2138e8b68e7814521bbfaad
http://hdl.handle.net/11585/682877
http://hdl.handle.net/11585/682877
Autor:
Hans-Georg Joost, Jerzy Adamski, Anna Floegel, Thomas Illig, Cornelia Prehn, Heiner Boeing, Dagmar Drogan, Rui Wang-Sattler, Tobias Pischon
Publikováno v:
PLoS ONE, Vol 6, Iss 6, p e21103 (2011)
PLoS ONE 6:e21103 (2011)
PLoS ONE
PLoS ONE 6:e21103 (2011)
PLoS ONE
Metabolomics is a promising tool for discovery of novel biomarkers of chronic disease risk in prospective epidemiologic studies. We investigated the between- and within-person variation of the concentrations of 163 serum metabolites over a period of