Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Ye Chen-Izu"'
Autor:
Sota Kudo, Zheng Chen, Xue Zhou, Leighton T. Izu, Ye Chen-Izu, Xin Zhu, Toshiyo Tamura, Shigehiko Kanaya, Ming Huang
Publikováno v:
Frontiers in Physiology. 14
Photoplethysmography (PPG) signal is potentially suitable in atrial fibrillation (AF) detection for its convenience in use and similarity in physiological origin to electrocardiogram (ECG). There are a few preceding studies that have shown the possib
Autor:
Balázs, Horváth, Norbert, Szentandrássy, Csaba, Dienes, Zsigmond M, Kovács, Péter P, Nánási, Ye, Chen-Izu, Leighton T, Izu, Tamas, Banyasz
Publikováno v:
Frontiers in Physiology. 13
The patch clamp technique underwent continual advancement and developed numerous variants in cardiac electrophysiology since its introduction in the late 1970s. In the beginning, the capability of the technique was limited to recording one single cur
Autor:
Mohammad A. Kazemi-Lari, John A. Shaw, Alan S. Wineman, Rafael Shimkunas, Zhong Jian, Bence Hegyi, Leighton Izu, Ye Chen-Izu
Publikováno v:
iScience, vol 25, iss 7
The heart pumps blood into circulation against vascular resistance and actively regulates the contractile force to compensate for mechanical load changes. Our experimental data show that cardiomyocytes have a mechano-chemo-transduction (MCT) mechanis
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, vol 118, iss 31
Proceedings of the National Academy of Sciences of the United States of America, vol 118, iss 31
Significance The heart autoregulates its contractile strength to maintain cardiac output when pumping blood against the mechanical afterload from vascular resistance. Increased afterload in cardiovascular diseases is associated with cardiac arrhythmi
Autor:
Zhong Jian, Leighton T. Izu, Mohammad A. Kazemi-Lari, Bence Hegyi, Rafael Shimkunas, Anthony J. Baker, Tamás Bányász, Ye Chen-Izu, John A. Shaw
Publikováno v:
Life
Life (Basel, Switzerland), vol 11, iss 6
Life, Vol 11, Iss 503, p 503 (2021)
Volume 11
Issue 6
Life (Basel, Switzerland), vol 11, iss 6
Life, Vol 11, Iss 503, p 503 (2021)
Volume 11
Issue 6
The heart has two intrinsic mechanisms to enhance contractile strength that compensate for increased mechanical load to help maintain cardiac output. When vascular resistance increases the ventricular chamber initially expands causing an immediate le
Publikováno v:
Can J Physiol Pharmacol
Canadian journal of physiology and pharmacology, vol 97, iss 8
Canadian journal of physiology and pharmacology, vol 97, iss 8
Hyperkalemia is known to develop in various conditions including vigorous physical exercise. In the heart, hyperkalemia is associated with action potential (AP) shortening that was attributed to altered gating of K+ channels. However, it remains unkn
Autor:
Yankun Lyu, Phung N. Thai, Lu Ren, Valeriy Timofeyev, Zhong Jian, Seojin Park, Kenneth S. Ginsburg, James Overton, Julie Bossuyt, Donald M. Bers, Ebenezer N. Yamoah, Ye Chen-Izu, Nipavan Chiamvimonvat, Xiao-Dong Zhang
Publikováno v:
iScience
iScience, vol 25, iss 1
iScience, Vol 25, Iss 1, Pp 103624-(2022)
iScience, vol 25, iss 1
iScience, Vol 25, Iss 1, Pp 103624-(2022)
Summary The mammalian heart beats incessantly with rhythmic mechanical activities generating acids that need to be buffered to maintain a stable intracellular pH (pHi) for normal cardiac function. Even though spatial pHi non-uniformity in cardiomyocy
Autor:
Donald M. Bers, Tamás Bányász, Penelope A. Boyden, Leighton T. Izu, Masahito Miura, Peter Kohl, Nipavan Chiamvimonvat, Natalia A. Trayanova, Ye Chen-Izu
Publikováno v:
The Journal of physiology, vol 598, iss 7
J Physiol
J Physiol
Cardiac excitation-contraction (E-C) coupling is influenced by (at least) three dynamic systems that couple and feedback to one another (Abstract Figure). Here we review the mechanical effects on cardiomyocytes that include mechano-electro-transducti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f41721d7c30e03e5f20d2de4616d8aa
https://escholarship.org/uc/item/2dj257vh
https://escholarship.org/uc/item/2dj257vh
Autor:
Donald M. Bers, Sridharan Rajamani, Leighton T. Izu, Bence Hegyi, Luiz Belardinelli, Tamás Bányász, Ye Chen-Izu
Publikováno v:
Circ Arrhythm Electrophysiol
Circulation. Arrhythmia and electrophysiology, vol 13, iss 4
Circulation. Arrhythmia and electrophysiology, vol 13, iss 4
Background: Rapid delayed rectifier K + current (I Kr ) and late Na + current (I NaL ) significantly shape the cardiac action potential (AP). Changes in their magnitudes can cause either long or short QT syndromes associated with malignant ventricula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24f64585715516bb012928d8c38d8dd2
https://europepmc.org/articles/PMC7331791/
https://europepmc.org/articles/PMC7331791/
Autor:
Xiao-Dong Zhang, Hannah A. Ledford, Ingrid Brust-Mascher, Gu Dai, Nipavan Chiamvimonvat, Padmini Sirish, Leighton T. Izu, Ye Chen-Izu, Zhong Jian, Jeong-Han Lee, Wei Chun Chen, Ebenezer N. Yamoah, Zana Coulibaly, Frank Y. S. Chuang
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-13 (2018)
Scientific reports, vol 8, iss 1
Scientific reports, vol 8, iss 1
Small-conductance Ca2+-activated K+ (SK) channels regulate the excitability of cardiomyocytes by integrating intracellular Ca2+ and membrane potentials on a beat-to-beat basis. The inextricable interplay between activation of SK channels and Ca2+ dyn