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pro vyhledávání: '"William C. Hunter"'
Autor:
William C. Hunter
Publikováno v:
Cardiology Clinics. 18:443-457
Myocardial relaxation is governed by the interplay of two macromolecular systems: (1) myofilaments and (2) calcium extruding pumps/exchangers. In myocardium from failing hearts, both systems act more slowly than normal, and cause relaxation to decele
Autor:
S Bier, D. Burkhoff, William C. Hunter, Matthew R. Wolff, David A. Kass, Y Harasawa, Gary Gerstenblith, P. P. De Tombe
Publikováno v:
Circulation Research. 70:516-529
The contributions of changes in primary systolic and diastolic properties, limitations of contractile reserve, and alterations in energy efficiency to the left ventricular dysfunction seen with chronic pacing tachycardia were investigated. Seven dogs
Publikováno v:
Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance. 5(4)
The effects of different pacing protocols on left ventricular (LV) torsion were evaluated over the full cardiac cycle. A systolic and diastolic series of magnetic resonance imaging (MRI) scans were combined and used to calculate the torsion of the LV
Autor:
Karl T. Weber, Sanjeev G. Shroff, Joseph S. Janicki, Alfred P. Fishman, Eugene S. Pearlman, William C. Hunter
Publikováno v:
Progress in cardiovascular diseases. 24(5)
The integrated function of the heart and lungs provides for the transfer of O 2 from the atmosphere, for its delivery to the metabolizing tissues, and for the removal of CO 2 . When cardiac output is compromised as in heart failure, a series of refle
Publikováno v:
The American journal of physiology. 246(1 Pt 2)
We measured cardiac mechanical restitution curves, which describe the time course of recovery of ventricular contractile strength following a steady-state beat. In the first series of experiments, we studied left ventricles that beat isovolumically t