Zobrazeno 11 - 15
of 15
pro vyhledávání: '"William C. Hunter"'
Publikováno v:
Circulation research. 71(2)
Myocardial oxygen consumption (MVO2) includes components for 1) mechanical energy generation, 2) activation, and 3) basal metabolism. Whereas the first two components are expected to increase in proportion with heart rate, a significant basal level o
Publikováno v:
The American journal of physiology. 260(4 Pt 2)
To determine the dynamic property of cardiac function response to alterations in coronary perfusion, we varied coronary arterial pressure (CAP) sinusoidally around one of four mean CAP levels with a constant amplitude at several frequencies in isolat
Publikováno v:
The American journal of physiology. 259(5 Pt 2)
Barium contracture tonically activates myocardium while preserving cellular integrity. We studied the metabolic and mechanical consequences of sustained Ba2+ contracture. We measured the time course of phosphocreatine (PCr), ATP, Pi, total phosphate,
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 253:H475-H479
The mechanical properties of the right and left ventricles (RV and LV) have previously been studied separately. However, because of differences in RV and LV architecture, geometry, and muscle mass, it is not obvious how the properties of the two cham
Publikováno v:
The American journal of physiology. 246(1 Pt 2)
We measured cardiac mechanical restitution curves, which describe the time course of recovery of ventricular contractile strength following a steady-state beat. In the first series of experiments, we studied left ventricles that beat isovolumically t
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