Zobrazeno 1 - 10
of 11
pro vyhledávání: '"William C. Hunter"'
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 272:H469-H477
Previous studies of regional differences in myocardial deformation between the anterior and posterior walls of the canine left ventricle were based on strain, which is not an absolute measure of deformation. We thus compared sarcomere lengths at ante
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 264:H1817-H1824
Recent clinical and animal studies have suggested that ventricular-vascular coupling normally operates at either optimal ventricular efficiency (EFF = stroke work/myocardial oxygen consumption) or stroke work (SW) and that efficiency in particular is
Autor:
H. F. Weisman, M. J. Royce, Edward K. Rodriguez, Michelle K. Leppo, A.S. Douglas, William C. Hunter
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 263:H293-H306
The ability to measure cyclic changes in myocardial sarcomere lengths and orientations during cardiac ejection and filling would improve our understanding of how the cellular processes of contraction relate to the pumping of the whole heart. Previous
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 260:H1596-H1611
Understanding the relationship between structure and function in the heart requires a knowledge of the connection between the local behavior of the myocardium (e.g., shortening) and the pumping action of the left ventricle. We asked the question, how
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 260:H569-H578
Recent studies have shown that at the same endsystolic volume, ejecting beats can achieve a higher end-systolic pressure than isovolumic beats. The purpose of this study was to assess the metabolic cost, in terms of oxygen consumption (MVO2), and eff
Publikováno v:
The American journal of physiology. 265(3 Pt 2)
This study focuses on elucidating how ventricular afterloading conditions affect the time course of change of left ventricular pressure (LVP) throughout the cardiac cycle, with particular emphasis on revealing specific limitations in the time-varying
Publikováno v:
Heart and vessels. 8(3)
Although pentobarbital has been found to depress myocardial function, the magnitude of its direct effects on ventricular contraction at anesthetic concentrations has not been well quantified. The direct effects of pentobarbital on left ventricular fu
Publikováno v:
Circulation research. 71(2)
Myocardial oxygen consumption (MVO2) includes components for 1) mechanical energy generation, 2) activation, and 3) basal metabolism. Whereas the first two components are expected to increase in proportion with heart rate, a significant basal level o
Publikováno v:
The American journal of physiology. 260(4 Pt 2)
To determine the dynamic property of cardiac function response to alterations in coronary perfusion, we varied coronary arterial pressure (CAP) sinusoidally around one of four mean CAP levels with a constant amplitude at several frequencies in isolat
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 253:H475-H479
The mechanical properties of the right and left ventricles (RV and LV) have previously been studied separately. However, because of differences in RV and LV architecture, geometry, and muscle mass, it is not obvious how the properties of the two cham