Zobrazeno 1 - 5
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pro vyhledávání: '"William C. Hunter"'
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 264:H1817-H1824
Recent clinical and animal studies have suggested that ventricular-vascular coupling normally operates at either optimal ventricular efficiency (EFF = stroke work/myocardial oxygen consumption) or stroke work (SW) and that efficiency in particular is
Publikováno v:
The American journal of physiology. 260(4 Pt 2)
To determine the dynamic property of cardiac function response to alterations in coronary perfusion, we varied coronary arterial pressure (CAP) sinusoidally around one of four mean CAP levels with a constant amplitude at several frequencies in isolat
Publikováno v:
Journal of Molecular and Cellular Cardiology. 20:415-426
To determine whether catecholamines produce alterations in myocardial myosin-actin cycling kinetics, we investigated the effects of isoproterenol upon mechanical characteristics of constantly activated heart muscle thought to reflect crossbridge beha
Publikováno v:
Circulation Research. 56:340-350
We established, for the isolated, isovolumically beating canine left ventricle, a comprehensive description of postextrasystolic contractile strength (dP/dtmax) as a function of extrasystolic and postextrasystolic stimulus intervals. In contrast to p
Publikováno v:
The American journal of physiology. 246(1 Pt 2)
We measured cardiac mechanical restitution curves, which describe the time course of recovery of ventricular contractile strength following a steady-state beat. In the first series of experiments, we studied left ventricles that beat isovolumically t