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Autor:
Marta Madeira, Natália António, Vera Marinho, J. Cristovao, Claudia Fernandes, Pedro Sousa, James Milner, Lino Gonçalves, Miguel Ventura, Luís Elvas
Publikováno v:
Journal of Cardiovascular Pharmacology. 79:e87-e93
Digoxin use in patients with heart failure with reduced ejection fraction (HFrEF) and sinus rhythm remains controversial. We aimed to assess the prognostic impact of digoxin in patients in sinus rhythm submitted to cardiac resynchronization therapy (
Autor:
Vanessa Melville, Nicola C. Edwards, Richard P. Steeds, Thomas F. Hiemstra, Anna S Herrey, Samir Mehta, Iain M. MacIntyre, Jonathan N. Townend, Amreen Kaur, Anna M Price, Tariq E. Farrah, Peter J. Greasley, Natalie Ives, Ian B. Wilkinson, David C. Wheeler, Rebekah Wale, Charles J. Ferro, Neeraj Dhaun, David J. Webb, Gemma Slinn
Publikováno v:
Edwards, N C, Price, A M, Mehta, S, Hiemstra, T F, Kaur, A, Greasley, P J, Webb, D J, Dhaun, N, MacIntyre, I M, Farrah, T, Melville, V, Herrey, A, Slinn, G, Wale, R, Ives, N, Wheeler, D C, Wilkinson, I, Steeds, R P, Ferro, C J & Townend, J N 2021, ' Effects of Spironolactone and Chlorthalidone on Cardiovascular Structure and Function in Chronic Kidney Disease : A Randomized, Open-Label Trial ', Clinical Journal of the American Society of Nephrology . https://doi.org/10.2215/CJN.01930221
Clin J Am Soc Nephrol
Clin J Am Soc Nephrol
Background and objectives In a randomized double-blind, placebo-controlled trial, treatment with spironolactone in early-stage CKD reduced left ventricular mass and arterial stiffness compared with placebo. It is not known if these effects were due t
Publikováno v:
Journal of Cardiovascular Pharmacology
Coronary heart disease (CHD) has become the primary cause of death worldwide in both developed and developing countries.1 In China, the mortality rates of CHD in urban and rural residents were 122.04/100,000 and 115.32/100,000, respectively, in 2017.
Autor:
Atsushi Tanaka, Takahisa Yamada, Hiroki Teragawa, Hirotsugu Yamada, Kazuki Shiina, Kaoru Dohi, Kenya Kusunose, Masataka Sata, Yasuchika Takeishi, Kazuo Eguchi, Koichi Node, Keisuke Kida, Takumi Imai, Candle Trial Investigators, Nobuyuki Ohte
Publikováno v:
Cardiovascular Diabetology, Vol 20, Iss 1, Pp 1-10 (2021)
Cardiovascular Diabetology
Cardiovascular Diabetology
Background Identification of the effective subtypes of treatment for heart failure (HF) is an essential topic for optimizing treatment of the disorder. We hypothesized that the beneficial effect of SGLT2 inhibitors (SGLT2i) on the levels of N-termina
Autor:
Christos Krogias, Fabienne Kreimer, Michael Gotzmann, Ralf Gold, Andreas Pflaumbaum, Andreas Mügge, Julian Felix Backhaus
Publikováno v:
Clinical Research in Cardiology
Background Thrombi and spontaneous echo contrast (SEC) in the left atrial appendage (LAA) are associated with thromboembolic events and poor prognosis. There are very few data on long-term outcome, especially with the use of direct acting anticoagula
Publikováno v:
Heart Rhythm. 18:1186-1191
Background Arrhythmogenic right ventricular cardiomyopathy (ARVC) is an important cause of sudden cardiac death in young people and athletes. To date, no treatment has proven to slow the progression of the disease. Preload reducing agents such as nit
Publikováno v:
Arthritis Care & Research. 73:828-832
OBJECTIVE To study the relationship between hydroxychloroquine (HCQ) use and new-onset atrial fibrillation in patients with systemic lupus erythematosus (SLE). METHODS A retrospective cohort of adult patients with SLE was constructed from December 1,
Autor:
Pradyumna Agasthi, Nirat Beohar, David R. Holmes, Mohamed Allam, Pattara Rattanawong, Sai Harika Pujari, Komandoor Srivathsan, Dan Sorajja, Win Kuang Shen, William K. Freeman, Ramila A. Mehta, Hicham El Masry, Farouk Mookadam, Eric H. Yang, Hasan Ashraf, Xiaoxi Yao, Anusha Shanbhag, Reza Arsanjani, Siva K. Mulpuru, Peter A. Noseworthy
Publikováno v:
The American Journal of Medicine. 134:788-796
Background Although direct oral anticoagulants (DOACs) have been shown to be effective at reducing the risk of stroke in patients with atrial fibrillation/flutter (AF), they are sometimes underdosed off-label to mitigate their associated higher bleed
Autor:
Huda El Mais, Yeung Yam, Benjamin J.W. Chow, Alomgir Hossain, Emel Celiker Guler, Gary R. Small, Kateleen Jia
Publikováno v:
Journal of Cardiovascular Computed Tomography. 15:226-231
Coronary CT angiography (CCTA) is increasing seen as a first line investigation in patients with suspected coronary artery disease. Heart-rate control improves the image quality and diagnostic accuracy of CCTA. Typically, beta-blockers are administer
Autor:
Michel Noutsias, Thomas G. Parker, Andreas S. Triantafyllis, Angelos G. Rigopoulos, James N. Tsoporis, Ioannis Rizos, Sahil Gupta, Andreas S Kalogeropoulos, Eleftherios A. Sakadakis
Publikováno v:
Journal of Cardiovascular Pharmacology. 77:360-369
Accumulating evidence indicates that heat shock proteins (HSPs) may represent a suitable biomarker to predict atrial fibrillation (AF). We investigated the relation of circulating serum HSP70 (sHSP70) with inflammatory cytokines and recurrence of sym