Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Yunshan Wang"'
Autor:
Yunshan Wang, Guangwei Wei, Jian-Hua Mao, Maoxiao Feng, Pengju Zhang, Huaizhi Wang, Zhongxi Zhao, Lei Bi
Publikováno v:
Oncogene
Oncogene, vol 40, iss 11
Oncogene, vol 40, iss 11
Genomic instability induced by DNA damage and improper DNA damage repair is one of the main causes of malignant transformation and tumorigenesis. DNA double strand breaks (DSBs) are the most detrimental form of DNA damage, and nonhomologous end-joini
Autor:
Lei Bi, Fuqiong Zhou, Peng Meng, Bo Tang, Yidan Ren, Yunshan Wang, Yu-Cui Jiang, Weiping Chen, Qin Wang, Chuanxin Wang, Maoxiao Feng, Yuli Wang, Feiyan Chen, Qinlian Jiao, Lutao Du
Publikováno v:
Cancer Research. 81:2015-2028
Hepatocellular carcinoma (HCC) contains a subset of cancer stem cells (CSC) that cause tumor recurrence, metastasis, and chemical resistance. Histone deacetylase 11 (HDAC11) mediates diverse immune functions and metabolism, yet little is known about
Autor:
Helen Binang, Mi Qi, Juan Li, Ning Li, Qing Wang, Peilong Li, Yingjie Chen, Yan Xie, Chuanxin Wang, Yanlei Wang, Haiting Mao, Yunshan Wang, Lili Wang, Lutao Du
Publikováno v:
Journal of Cellular and Molecular Medicine
Long non‐coding RNAs (lncRNAs) have come out as critical molecular regulators of human tumorigenesis. In this study, we sought to identify and functionally characterize lncRNAs as potential mediators of colorectal cancer progression. We screened an
Autor:
Yunshan Wang, Yuli Wang, Yidan Ren, Fang Wang, Peilong Li, Peng Meng, Chuanxin Wang, Juan Li, Qinlian Jiao, Xiaoyan Liu, Lutao Du
Publikováno v:
Theranostics
Rationale: It has been proposed that cancer stem/progenitor cells (or tumor-initiating cells, TICs) account for breast cancer initiation and progression. Sirtuins are nicotinamide adenine dinucleotide (NAD+)-dependent class-III histone deacetylases a
Autor:
Yunshan Wang, Ji-Eun Kim, Roshane Francis, Shaheed W Hakim, Jung-Eun Kim, Housheng Hansen He, Jieun Seo, Tae-Hee Kim, Haiyang Guo, Adrian Kwan Ho Loe, Lutao Du
Publikováno v:
The Journal of Experimental Medicine
Loe et al. demonstrate dosage-dependent roles of Arid1a, whereby the loss of its single copy promotes tumor progression, but tumor cells lacking both copies exhibit a survival disadvantage. This finding leads to a novel combined targeting approach fo
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 38, Iss 1, Pp 1-13 (2019)
Journal of Experimental & Clinical Cancer Research : CR
Journal of Experimental & Clinical Cancer Research : CR
Background Ubiquitin E3 ligase CUL4A plays important oncogenic roles in the development of cancers. DTL, one of the CUL4-DDB1 associated factors (DCAFs), may involve in the process of cancer development. Programmed cell death 4 (PDCD4) is a tumor sup
Publikováno v:
Hepatology. 69:1614-1631
Sirtuin 4 (SIRT4) has been reported to play a vital role in the maintenance of glutamine catabolism and adenosine triphosphate (ATP) homeostasis, but its character in hepatocellular carcinomas (HCCs) remains obscure. In this study, we observed low ex
Autor:
Hongliang Dai, Lutao Du, Yunshan Wang, Bo Tang, Yang Li, Yidan Ren, Min Kang, Yumin Wang, Maoxiao Feng
Publikováno v:
Cancer research. 81(14)
Exploiting cancer metabolism for the clinical benefit of patients with hepatocellular carcinoma (HCC) is a topic under active investigation. Ubiquitin-specific peptidase 48 (USP48), a member of the ubiquitin-specific protease family, is involved in t
Autor:
Weili Duan, Xue Kong, Juan Li, Peilong Li, Yinghui Zhao, Tong Liu, Helen Barong Binang, Yunshan Wang, Lutao Du, Chuanxin Wang
Publikováno v:
Frontiers in Cell and Developmental Biology
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Accumulating literatures have indicated that long non-coding RNAs (lncRNAs) are crucial molecules in tumor progression in various human cancers, including colorectal cancer (CRC). However, the clinical significance and regulatory mechanism of a vast
Autor:
Xuemei Yang, Juan Li, Yifan Wang, Peilong Li, Yinghui Zhao, Weili Duan, Abakundana Nsenga Ariston Gabriel, Yingjie Chen, Haiting Mao, Yunshan Wang, Lutao Du, Chuanxin Wang
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
Frontiers in Oncology
Frontiers in Oncology
Deregulations of long non-coding RNAs (lncRNAs) have been implicated in the progression of breast cancer (BC). However, the prognostic values of those lncRNAs in BC remain elusive. This study aimed at constructing a lncRNA-based prognostic model to i