Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Payam Fathi"'
Autor:
Ye Yang, Raad Z. Gharaibeh, Payam Fathi, Shaoguang Wu, Liam Chung, Anthony A. Fodor, Sarah Tomkovich, Sepideh Besharati, Marcus Mühlbauer, James R. White, Jillian L. Pope, Cynthia L. Sears, Ernesto Perez-Chanona, Drew M. Pardoll, Julia L. Drewes, Kathryn Winglee, Xinqun Wu, Robert A. Anders, Christian Jobin, Franck Housseau, Christine M. Dejea, Hao Wang, Xiaolun Sun, Josee Gauthier, Xiuli Liu, Hua Ding
Publikováno v:
Journal of Clinical Investigation. 129:1699-1712
Mucus-invasive bacterial biofilms are identified on the colon mucosa of approximately 50% of colorectal cancer (CRC) patients and approximately 13% of healthy subjects. Here, we test the hypothesis that human colon biofilms comprise microbial communi
Patients with familial adenomatous polyposis harbor colonic biofilms containing tumorigenic bacteria
Autor:
John M. Craig, Shaoguang Wu, Christina E. DeStefano Shields, Xinqun Wu, Robert A. Anders, Christine M. Dejea, Rahwa Taddese, Hao Wang, Abby L. Geis, David L. Huso, Drew M. Pardoll, Francis M. Giardiello, Elizabeth C. Wick, Annemarie Boleij, Franck Housseau, Payam Fathi, Elizabeth M. Hechenbleikner, Cynthia L. Sears
Publikováno v:
Science, 359, 6375, pp. 592-597
Science, 359, 592-597
Science, 359, 592-597
Biofilms provide refuge for cancerous bacteria Familial adenomatous polyposis (FAP) causes benign polyps along the colon. If left untreated, FAP leads to a high incidence of colon cancer. To understand how polyps influence tumor formation, Dejea et a
Autor:
Fengyi Wan, Paul Metz, Sudipto Ganguly, Drew M. Pardoll, Hongni Fan, Christina E. DeStefano Shields, David L. Huso, Florencia McAllister, Kai Fu, Shaoguang Wu, Benjamin B. Finard, June Chan, Payam Fathi, Jie Chen, Ada J. Tam, Cynthia L. Sears, Franck Housseau, Christine M. Dejea, Abby L. Geis, Elizabeth C. Wick, Sara W. Van Meerbeke, Liam Chung, Erik Thiele-Orberg, Xinqun Wu
Publikováno v:
SSRN Electronic Journal.
Pro-carcinogenic bacteria have the potential to initiate and/or promote human colon cancer. However, the mechanism(s) by which a bacterium may trigger carcinogenesis remains unclear. Herein, we show Bacteroides fragilis toxin (BFT) secretion by the h
Autor:
Shaoguang Wu, Cynthia L. Sears, Franck Housseau, E. Thiele Orberg, Payam Fathi, Ada Tam, Sudipto Ganguly, Hongni Fan, Drew M. Pardoll, Juan Fu, Xinqun Wu, C E Destefano Shields, Benjamin B. Finard, Christine M. Dejea, Liam Chung
Publikováno v:
Mucosal immunology
Enterotoxigenic Bacteroides fragilis (ETBF), a human commensal and candidate pathogen in colorectal cancer (CRC), is a potent initiator of interleukin-17 (IL-17)-dependent colon tumorigenesis in MinApc+/- mice. We examined the role of IL-17 and ETBF
Autor:
Hongni Fan, Cynthia L. Sears, Christine M. Dejea, Shaoguang Wu, Benjamin B. Finard, Abby L. Geis, Xinqun Wu, Christina E. DeStefano Shields, David L. Huso, Elizabeth C. Wick, Kai Fu, June L. Chan, Ada J. Tam, Sara W. Van Meerbeke, Liam Chung, Fengyi Wan, Florencia McAllister, Erik Thiele Orberg, Payam Fathi, Andriana Lebid, Franck Housseau, Drew M. Pardoll, Jie Chen, Paul Metz, Sudipto Ganguly
Publikováno v:
Cell host & microbe, vol 23, iss 2
Summary Pro-carcinogenic bacteria have the potential to initiate and/or promote colon cancer, in part via immune mechanisms that are incompletely understood. Using Apc Min mice colonized with the human pathobiont enterotoxigenic Bacteroides fragilis