Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Nicola Parry"'
Autor:
Qiyuan Han, Steven R. Tannenbaum, Christopher L. Seiler, Natalia Y. Tretyakova, Thomas J. Y. Kono, James G. Fox, Nicola Parry, Charles G. Knutson
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 364, p 364 (2021)
International Journal of Molecular Sciences
Volume 22
Issue 1
International Journal of Molecular Sciences
Volume 22
Issue 1
Epigenetic dysregulation is hypothesized to play a role in the observed association between inflammatory bowel disease (IBD) and colon tumor development. In the present work, DNA methylome, hydroxymethylome, and transcriptome analyses were conducted
Autor:
James G. Fox, Bernard J. Varian, Sravya Gourishetti, Zhongming Ge, Jerrold M. Ward, Brett Fisher, Susan E. Erdman, Ellen C. Teng, Nicola Parry, Tatiana Levkovich, Jessica R. Lakritz, Theofilos Poutahidis, Yassin M. Ibrahim, Sheyla Mirabal, Natalie Alberg, Stephanie Lesage
Publikováno v:
Oncotarget
Recent studies suggest that gastrointestinal tract microbiota modulate cancer development in distant non-intestinal tissues. Here we tested mechanistic hypotheses using a targeted pathogenic gut microbial infection animal model with a predilection to
Publikováno v:
PMC
Multiple pathogenic Gram-negative bacteria produce the cytolethal distending toxin (CDT) with activity of DNase I; CDT can induce DNA double-strand breaks (DSBs), G2/M cell cycle arrest, and apoptosis in cultured mammalian cells. However, the link of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ad07f1011437229be5fbdfe952c2812
http://hdl.handle.net/1721.1/120745
http://hdl.handle.net/1721.1/120745
Autor:
Jennifer A. Sanders, Philip A. Gruppuso, Nicola Parry, Kate E. Brilliant, Heather Francois-Vaughan, Adeola O. Adebayo
Hepatocellular carcinoma (HCC) is a heterogeneous disease in which tumor sub-types can be identified based on the presence of adult liver progenitor cells. Having previously identified the mTOR pathway as critical to progenitor cell proliferation in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e250bff44e3638085e0b1cbff289ba48
https://europepmc.org/articles/PMC5006212/
https://europepmc.org/articles/PMC5006212/
Autor:
Aswin Mangerich, Jose L. McFaline, Nicola Parry, Koli Taghizadeh, Charles G. Knutson, Zhongming Ge, Steven R. Tannenbaum, James G. Fox, Gerald N. Wogan, Melissa W. Mobley, Sureshkumar Muthupalani, Wenjie Ye, Peter C. Dedon, John S. Wishnok, Erin G. Prestwich, Liang Cui
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 109(27)
Helicobacter hepaticus -infected Rag 2 -/- mice emulate many aspects of human inflammatory bowel disease, including the development of colitis and colon cancer. To elucidate mechanisms of inflammation-induced carcinogenesis, we undertook a comprehens
Autor:
Melissa W. Mobley, Arkadiusz R. Raczynski, Julia E. Rager, Sureshkumar Muthupalani, Timothy C. Wang, James G. Fox, Nicola Parry, Rebecca C. Fry, Zhongming Ge, Alexander Sheh, Amanda McCabe
Publikováno v:
PMC
Helicobacter pylori infection promotes male predominant gastric adenocarcinoma in humans. Estrogens reduce gastric cancer risk and previous studies showed that prophylactic 17β-estradiol (E2) in INS-GAS mice decreases H. pylori–induced carcinogene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11a714ea2023708d03ff8828599ff656
https://europepmc.org/articles/PMC3168115/
https://europepmc.org/articles/PMC3168115/