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pro vyhledávání: '"Marlon R. Lutz"'
Autor:
Sebastian Flieger, Mao Takagaki, Natsuko Kondo, Marlon R. Lutz, Yash Gupta, Hiroki Ueda, Yoshinori Sakurai, Graham Moran, Prakasha Kempaiah, Narayan Hosmane, Minoru Suzuki, Daniel P. Becker
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 8, p 6973 (2023)
New carborane-bearing hydroxamate matrix metalloproteinase (MMP) ligands have been synthesized for boron neutron capture therapy (BNCT) with nanomolar potency against MMP-2, -9 and -13. New analogs are based on MMP inhibitor CGS-23023A, and two previ
Externí odkaz:
https://doaj.org/article/a85245bac78c4eee8c71305b987c263a
Autor:
Marlon R. Lutz, Sebastian Flieger, Andre Colorina, Daniel P. Becker, Narayan S. Hosmane, John Wozny
Publikováno v:
ChemMedChem. 15(20)
Based on the previously reported potent and selective sulfone hydroxamate inhibitors SC-76276, SC-78080 (SD-2590), and SC-77964, potent MMP inhibitors have been designed and synthesized to append a boron-rich carborane cluster by employing click chem
Autor:
Daniel P. Becker, Marlon R. Lutz, Narayan S. Hosmane, Andre Colorina, John Wozny, Sebastian Flieger
Publikováno v:
ChemMedChem. 15:1861-1861