Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Karoline, Horisberger"'
Autor:
Peter Kienle, S. Mai, Melanie Kripp, R.D. Hofheinz, Timo Gaiser, F. Wenz, Karoline Horisberger, Kirsten Merx, Stefan Post
Publikováno v:
Gastroenterology Research and Practice
Gastroenterology Research and Practice, Vol 2015 (2015)
Gastroenterology Research and Practice, Vol 2015 (2015)
Purpose. The addition of cetuximab to radiochemotherapy (RCT) failed to improve complete response rates in locally advanced rectal cancer (LARC). We report the long-term results in patients treated within two sequential clinical trials.Methods. Patie
Autor:
Beatrice Bohn, Frederik Wenz, Peter Kienle, Georg Kähler, Benjamin Hanfstein, Stefan Post, Ralf-Dieter Hofheinz, Philipp Erben, Karoline Horisberger, Andreas Hochhaus, Juliana Popa, Philipp Ströbel
Publikováno v:
International Journal of Radiation Oncology*Biology*Physics. 81:1032-1038
Purpose Mutations in KRAS and BRAF genes as well as the loss of expression of phosphatase and tensin homolog (PTEN) (deleted on chromosome 10) are associated with impaired activity of antibodies directed against epidermal growth factor receptor in pa
Autor:
Philipp Ströbel, Andreas Hochhaus, Frederik Wenz, Stefan Post, Ralf-Dieter Hofheinz, Georg Kähler, Manuel Barreto-Miranda, Dietmar Dinter, Karoline Horisberger, Peter Kienle, Sabine Mai, Anne Treschl, Philipp Erben, Frank Willeke, Christoph M. Woernle
Publikováno v:
International Journal of Radiation Oncology*Biology*Physics. 74:1487-1493
Purpose To evaluate the safety and efficacy of preoperative radiotherapy (RT) in combination with cetuximab, capecitabine, and irinotecan in patients with locally advanced rectal cancer. Methods and Materials Patients with rectal cancer (clinical sta
Autor:
Andreas Hochhaus, Stefan Post, Karoline Horisberger, Frank Willeke, Philipp Erben, Christoph M. Woernle, Ralf-Dieter Hofheinz, Frederik Wenz, Philipp Stroebel, Benjamin Muessle, Georg Kaehler
Publikováno v:
Anti-Cancer Drugs. 20:519-524
Biomarkers may help predict the efficacy of neoadjuvant chemoradiation in patients with rectal cancer. We hypothesized that the expression of topoisomerase I (Topo I) and thymidylate synthase (TS) may help predict the treatment response in patients u
Autor:
Armin Leitner, Rainer Grobholz, R.D. Hofheinz, Frank Willeke, Andreas Hochhaus, Karoline Horisberger, F. Wenz, A. Willer, Georg Kähler, Stefan Post, Uta Kraus-Tiefenbacher
Publikováno v:
British Journal of Cancer
We sought to evaluate the efficacy and safety data of a combination regimen using weekly irinotecan in combination with capecitabine and concurrent radiotherapy (CapIri-RT) as neoadjuvant treatment in rectal cancer in a phase-II trial. Patients with
Autor:
Frank Willeke, Stefan Post, Steffen Heeger, Dietmar Dinter, Karoline Horisberger, Uta Kraus-Tiefenbacher, Andreas Hochhaus, Georg Kähler, Rainer Grobholz, Frederik Wenz, Christoph M. Woernle, Ralf-Dieter Hofheinz
Publikováno v:
International journal of radiation oncology, biology, physics. 66(5)
Purpose: To establish the feasibility and efficacy of chemotherapy with capecitabine, weekly irinotecan, cetuximab, and pelvic radiotherapy for patients with locally advanced rectal cancer. Methods and materials: Twenty patients with rectal cancer (c
Autor:
Wolf-Karsten Hofmann, Stefan Post, Deniz Gencer, Philipp Ströbel, Peter Kienle, Karoline Horisberger, Beatrice Bohn, Frederik Wenz, Juliana Schwaab, Georg Kähler, Ralf-Dieter Hofheinz, Philipp Erben
Publikováno v:
BMC Cancer
BMC Cancer, Vol 11, Iss 1, p 363 (2011)
BMC Cancer, Vol 11, Iss 1, p 363 (2011)
Background For patients with locally advanced rectal cancer (LARC) neoadjuvant chemoradiotherapy is recommended as standard therapy. So far, no predictive or prognostic molecular factors for patients undergoing multimodal treatment are established. I