Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Zewen K. Tuong"'
Autor:
Yikun Yao, Ping Du Jiang, Brittany N. Chao, Deniz Cagdas, Satoshi Kubo, Arasu Balasubramaniyam, Yu Zhang, Bella Shadur, Adeeb NaserEddin, Les R. Folio, Benjamin Schwarz, Eric Bohrnsen, Lixin Zheng, Matthew Lynberg, Simone Gottlieb, Michael A. Leney-Greene, Ann Y. Park, Ilhan Tezcan, Ali Akdogan, Rahsan Gocmen, Sevgen Onder, Avi Rosenberg, Elizabeth J. Soilleux, Errin Johnson, Peter K. Jackson, Janos Demeter, Samuel D. Chauvin, Florian Paul, Matthias Selbach, Haydar Bulut, Menna R. Clatworthy, Zewen K. Tuong, Hanlin Zhang, Benjamin J. Stewart, Catharine M. Bosio, Polina Stepensky, Simon Clare, Sundar Ganesan, John C. Pascall, Oliver Daumke, Geoffrey W. Butcher, Andrew J. McMichael, Anna Katharina Simon, Michael J. Lenardo
Inborn errors of immunity (IEIs) unveil regulatory pathways of human immunity. We describe a new IEI caused by mutations in the GTPase of the immune-associated protein 6 (GIMAP6) gene in patients with infections, lymphoproliferation, autoimmunity, an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e875cafd6e83da3c9610e843fba1a87e
http://edoc.mdc-berlin.de/21629/1/21629oa.pdf
http://edoc.mdc-berlin.de/21629/1/21629oa.pdf
Autor:
Siok Min Teoh, Paula Kuo, Janin Chandra, Ian H. Frazer, Lynn Tolley, Chengzhong Yu, Zibin Chen, Abate Assefa Bashaw, James W. Wells, Meihua Yu, Yang Liu, Zewen K. Tuong
Publikováno v:
The Journal of Immunology. 206:987-998
Prophylactic human papillomavirus (HPV) vaccines are commercially available for prevention of infection with cancerogenic HPV genotypes but are not able to combat pre-existing HPV-associated disease. In this study, we designed a nanomaterial-based th
Autor:
Joseph E. Powell, Samuel W. Lukowski, Chenhao Zhou, Kevin R. Gillinder, John R. Ferdinand, Quan Nguyen, Benjamin J. Stewart, Sarah J. Hanson, Menna R. Clatworthy, Abate Assefa Bashaw, Katharina Devitt, Janin Chandra, Zewen K. Tuong, Ian H. Frazer, Siok Min Teoh
Publikováno v:
iScience
iScience, Vol 24, Iss 11, Pp 103326-(2021)
iScience, Vol 24, Iss 11, Pp 103326-(2021)
Summary Langerhans cells (LC) are skin-resident antigen-presenting cells that regulate immune responses to epithelial microorganisms. Human papillomavirus (HPV) infection can promote malignant epithelial transformation. As LCs are considered importan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5489e12553035dc9d1ea9bb4e5a522b4
Autor:
Samuel W. Lukowski, H. Peter Soyer, Ian H. Frazer, Erin McMeniman, Katharina Devitt, Zewen K. Tuong, Sarah J. Hanson
Publikováno v:
Virology. 537:14-19
Human Papillomavirus infection is highly prevalent worldwide. While most types of HPV cause benign warts, some high-risk types are known to cause cervical cancer, as well as cancer of the oral cavity and head and neck. Persistent cutaneous HPV infect
Autor:
Raymond J. Steptoe, Andrew W. Lewandowski, James W. Wells, H. Peter Soyer, Fiona Simpson, Graham R. Leggatt, Ian H. Frazer, Duncan Lambie, Miko Yamada, Zewen K. Tuong, Richard Lewandowski, Jazmina L. G. Cruz, Jennifer A. Bridge
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-11 (2019)
Scientific Reports
Scientific Reports
Actinic Keratosis (AK), Intraepidermal Carcinoma (IEC), and Squamous Cell Carcinoma (SCC) are generally considered to be advancing stages of the same disease spectrum. However, while AK often regress spontaneously, and IEC often regress in response t
Autor:
Ravindra K. Gupta, Prasanti Kotagiri, James A. Nathan, Stephen Baker, Nicholas J Matheson, Berthold Göttgens, Paul A. Lyons, Natalie Burrows, Mark Toshner, John Bradley, Stephen Moore, Aimee Hanson, Patrick H. Maxwell, Zewen K. Tuong, Rachael Bashford Rogers, Myra Hosmillo, Christoph Hess, Ian Goodfellow, Laura Bergamaschi, Benjamin J. Dunmore, Brian Ortmann, Menna R. Clatworthy, Nathalie Kingston, Lorinda Turner, Kenneth G. C. Smith, Michael P. Weekes, Caroline Saunders, Paul J. Lehner, Hélène Ruffieux, Michael D Morgan, Sylvia Richardson, Anne Elmer, Federica Mescia, Nathan Richoz, Ana Peñalver
Prominent early features of COVID-19 include severe, often clinically silent, hypoxia and a pronounced reduction in B cells, the latter important in defence against SARS-CoV-2. This brought to mind the phenotype of mice with VHL-deficient B cells, in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9ef618485083efcf05792572267572e7
https://doi.org/10.1101/2021.07.12.21260360
https://doi.org/10.1101/2021.07.12.21260360
Autor:
Zhen Zeng, James W. Wells, Ian H. Frazer, Margaret Veitch, Jazmina Gonzalez Cruz, Zewen K. Tuong, Gabrielle A. Kelly
Publikováno v:
Cancers, Vol 13, Iss 2131, p 2131 (2021)
Cancers
Volume 13
Issue 9
Cancers
Volume 13
Issue 9
Simple Summary Cutaneous squamous cell carcinoma (SCC) is prevalent in aged individuals and individuals with compromised or weakened immune systems, indicating a close association between immune function and SCC control. The aim of our study was to u
Autor:
Zewen K. Tuong, Renee Gloury, Graham R. Leggatt, Takumi Kobayashi, Valentine Murigneux, Maher K. Gandhi, Rui Li, Axel Kallies, Karolina Bednarska, Stephen R. Mattarollo, Joshua Tay, Shyuan T. Ngo, Gabrielle T. Belz, Hui Jiang, Michelle M. Hill, Pui Yeng Lam, Nicolas Jacquelot
Publikováno v:
Blood. 136(26)
Natural killer (NK) cells play critical roles in protection against hematological malignancies but can acquire a dysfunctional state, which limits antitumor immunity. However, the underlying reasons for this impaired NK cell function remain to be unc
HPV16E7-Induced Hyperplasia Promotes CXCL9/10 Expression and Induces CXCR3+ T-Cell Migration to Skin
Autor:
Zewen K. Tuong, Graham R. Leggatt, Ian H. Frazer, Stephen Œr. Mattarollo, Paula Kuo, Siok Min Teoh
Publikováno v:
Journal of Investigative Dermatology. 138:1348-1359
Chemokines regulate tissue immunity by recruiting specific subsets of immune cells. Mice expressing the E7 protein of human papilloma virus 16 as a transgene from a keratin 14 promoter (K14.E7) show increased epidermal and dermal lymphocytic infiltra
Autor:
Hui Yi Chew, Margaret Veitch, Jazmina L. G. Cruz, Xuzhi He, Shannon R. Joseph, James W. Wells, Nicola Pett, Gabrielle A. Kelly, Zewen K. Tuong, Fiona Simpson, Satomi Okano
Publikováno v:
Oncotarget
The Epidermal Growth Factor Receptor (EGFR) is selectively expressed on the surface of numerous tumours, such as non-small cell lung, ovarian, colorectal and head and neck carcinomas. EGFR has therefore become a target for cancer therapy. Cetuximab i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::676104c24576f2733ac56ecce95694d2