Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Xiaofeng Tian"'
Autor:
Xuebo Chen, Xiaofeng Tian, Xuedong Fang, Dingquan Yang, Shengnan Ren, Fangfang Chen, Yongli Dong
Publikováno v:
Translational Cancer Research
Objective Protamine 1 (PRM1) is specific in sperm and plays essential roles in fertilization, also a member of cancer testis antigen (CTA) family. This study aims to summarize the expression and function of PRM1 in spermatogenesis, and to broaden the
Autor:
Zhao Chen, Xiaodong Ma, Li Lv, Xiaofeng Tian, Fan Tang, Huanyu Zhao, Yang Li, Jihong Yao, Zhecheng Wang, Junjun Zhou, Dongcheng Feng, Yan Zhao
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 21, Iss, Pp 751-763 (2020)
Molecular Therapy. Nucleic Acids
Molecular Therapy. Nucleic Acids
We previously found that inhibition of p66Shc confers protection against hepatic stellate cell (HSC) activation during liver fibrosis. However, the effect of p66Shc on HSC proliferation, as well as the mechanism by which p66Shc is modulated, remains
Autor:
Junjun Zhou, Yan Zhao, Ruimin Sun, Jihong Yao, Dongcheng Feng, Rong Fu, Xiaofeng Tian, Zhecheng Wang, Ruiwen Wang, Li Lv
Publikováno v:
Oxidative Medicine and Cellular Longevity, Vol 2019 (2019)
Oxidative Medicine and Cellular Longevity
Oxidative Medicine and Cellular Longevity
Alcohol abuse has become common worldwide and has been recognized as a major cause of chronic alcoholic liver disease (ALD). ALD encompasses a complex process that includes a broad scope of hepatic lesions, ranging from steatosis to cirrhosis. In par
Autor:
Tong Li, Xiaofeng Tian, Guo Zu, Anlong Ji, Yang Li, Guangzhi Wang, Dongcheng Feng, Jihong Yao
Publikováno v:
World Journal of Gastroenterology
BACKGROUND Intestinal ischemia reperfusion (I/R) injury is a serious but common pathophysiological process of many diseases, resulting in a high mortality rate in clinical practice. Ubiquitin-specific protease 22 (USP22) acts as regulator of cell cyc
Autor:
Yan Zhao, Musen Lin, Deshun Liu, Yu Sun, Zhao Chen, Ruimin Sun, Jihong Yao, Junjun Zhou, Zhecheng Wang, Li Lv, Xiaofeng Tian
Publikováno v:
Cell Death & Disease
Cell Death and Disease, Vol 11, Iss 11, Pp 1-15 (2020)
Cell Death and Disease, Vol 11, Iss 11, Pp 1-15 (2020)
p66Shc, a master regulator of mitochondrial reactive oxygen species (mtROS), is a crucial mediator of hepatocyte oxidative stress. However, its functional contribution to acetaminophen (APAP)-induced liver injury and the mechanism by which it is modu
Autor:
Yan Hu, Zhecheng Wang, Yan Zhao, Dongcheng Feng, Yang Li, Jihong Yao, Junjun Zhou, Xiaofeng Tian, Chao Wang, Fan Tang, Huanyu Zhao
Publikováno v:
Pharmacological Research. 128:327-337
Quiescent hepatic stellate cell (HSC) activation and subsequent conversion into myofibroblasts is the central event in hepatic fibrosis pathogenesis. Epithelial-mesenchymal transition (EMT), another vital participant in liver fibrosis, has the potent
Autor:
Anlong Ji, Dongcheng Feng, Guo Zu, Jihong Yao, Fuwen Luo, Yiqi Rui, Guangzhi Wang, Zhenlu Li, Shili Ning, Yang Li, Xiaofeng Tian
Publikováno v:
Journal of Molecular Medicine. 95:83-95
Intestinal ischemia/reperfusion (I/R) injury is a potentially life-threatening condition that can cause injuries to remote organs at the end stage. The damage caused by intestinal I/R insult induces changes in the barrier functions of the intestine,
Autor:
Yan Zhao, Chao Wang, Zhenlu Li, Dongyan Gao, Shuai Zhang, Xiaofeng Tian, Ting Xu, Ruiwen Wang, Jihong Yao, Yan Hu, Junjun Zhou, Jie Zhu
Publikováno v:
Frontiers in Pharmacology, Vol 9 (2018)
Frontiers in Pharmacology
Frontiers in Pharmacology
Background: Endoplasmic reticulum stress (ER stress) plays a critical role in the pathogenesis of liver fibrosis; thus, it can be a potential therapeutic target of fibrosis. However, the mechanism of ER stress regulation in fibrosis, particularly thr
Autor:
Feng Zhang, Wei Zhou, Huanyu Zhao, Dongcheng Feng, Jihong Yao, Zhenlu Li, Xiaofeng Tian, Wenzhi Tan, Yang Li, Liwei Liu
Publikováno v:
Apoptosis : an international journal on programmed cell death. 23(11-12)
Epithelial apoptosis is an important factor in intestinal ischemia-reperfusion (I/R) injury. Heat shock factor 1 (HSF1) is a classical stress response factor that directly regulates the transcription of heat shock proteins (HSPs) under stress conditi
Autor:
Jie Zhu, Dongcheng Feng, Yan Zhao, Zhenlu Li, Guo Zu, Xiaofeng Tian, Jihong Yao, Zishuo Wang, Feng Zhang, Shili Ning, Yang Li, Guangzhi Wang
Publikováno v:
Shock (Augusta, Ga.). 52(3)
Intestinal ischemia/reperfusion (I/R)-induced systemic inflammation leads to multiple organ dysfunction syndrome. Previous studies have indicated that the NOD-like receptor protein (NLRP)3 inflammasome modulates intestinal inflammation; however, the