Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Richard P, Lifton"'
Autor:
Gloria S. Huang, Roberto Angioli, Titus J. Boggon, Weilai Dong, Ludmil B. Alexandrov, Gulden Menderes, Elena Bonazzoli, Francesco Raspagliesi, Richard P. Lifton, Chanhee Han, Aranzazu Manzano, Franco Odicino, Peter E. Schwartz, Antonella Ravaggi, Kaya Bilguvar, Emanuele Perrone, Laura Zanotti, Elena Ratner, Salvatore Lopez, Laura Ardighieri, Joseph Schlessinger, Valentina Pirazzoli, Jungmin Choi, Gary Altwerger, Francesca Pettinella, Siming Zhao, Alessandro D. Santin, Masoud Azodi, Carla Donzelli, Luca Zammataro, Natalia Buza, Paola Todeschini, Burak Zeybek, Dan-Arin Silasi, Eliana Bignotti, Stefania Bellone, Sergio Pecorelli, Pei Hui, Chiara Romani, Serena Wong, Amy L. Stiegler, Emiliano Cocco, Paola Manara, Giovanni Scambia, Anna Bianchi
Publikováno v:
Proceedings of the National Academy of Sciences. 116:22730-22736
The prognosis of advanced/recurrent cervical cancer patients remains poor. We analyzed 54 fresh-frozen and 15 primary cervical cancer cell lines, along with matched-normal DNA, by whole-exome sequencing (WES), most of which harboring Human-Papillomav
Autor:
James R. Knight, Norman G. Nicolson, Richard P. Lifton, John W. Kunstman, Shrikant Mane, Reju Korah, Tobias Carling, Sara Abou Azar, Andrea Barbieri, Weilai Dong, Kaya Bilguvar, Jungmin Choi
Publikováno v:
Genes, Chromosomes and Cancer. 57:645-652
Foci of papillary or follicular thyroid carcinoma are frequently noted in thyroidectomy specimens of anaplastic thyroid carcinoma (ATC). However, whether ATCs evolve from these co-existing well-differentiated thyroid carcinomas (WDTCs) has not been w
Autor:
Franco Odicino, Samir Zaidi, Nupur Nagarkatti, Gary Altwerger, Laura Zanotti, Alessandro D. Santin, Elena Bonazzoli, Kyungjo Jeong, Gloria S. Huang, Dan-Arin Silasi, Adele Guglielmi, Burak Zeybek, Richard P. Lifton, Luca Zammataro, Dennis Mauricio, Aranzazu Manzano, Gulden Menderes, Barbara Gnutti, Justin Harold, Siming Zhao, Laura Ardighieri, Jungmin Choi, Vaagn Andikyan, Elena Ratner, Chiara Romani, Pei Hui, Xiaotong Yao, Eliana Bignotti, Antonella Ravaggi, Masoud Azodi, Stefania Bellone, Joseph Schlessinger, Joan Tymon-Rosario, Natalia Buza, Ludmil B. Alexandrov, Weilai Dong, Paola Todeschini, Marcin Imielinski, Kaya Bilguvar, Mitchell Clark, Peter E. Schwartz, Charles M. Quick, Sergio Pecorelli, Aditya Deshpande
Publikováno v:
Proc Natl Acad Sci U S A
Uterine leiomyosarcomas (uLMS) are aggressive tumors arising from the smooth muscle layer of the uterus. We analyzed 83 uLMS sample genetics, including 56 from Yale and 27 from The Cancer Genome Atlas (TCGA). Among them, a total of 55 Yale samples in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d29b1daa57773373079eeec2397f029d
https://hdl.handle.net/11379/568771
https://hdl.handle.net/11379/568771
Autor:
F. Gregory Wulczyn, Claudia Marini, Carol Nelson-Williams, Daniel J. Foster, William J. Sullivan, Suel Kee Kim, Todd Constable, Elisa Cuevas, Richard P. Lifton, Waldemar Kolanus, June Goto, August A Allocco, Mingfeng Li, Charuta G. Furey, Yonghyun Ha, Le Hao, Xue Zeng, Sheng Chih Jin, Arnaud Marlier, Haifan Lin, Bettina Jux, Duy Phan, Amar H. Sheth, Yiying Yang, Evelyn Lake, Lucia A. Torres-Fernández, Weilai Dong, Frank J. Slack, Benjamin C. Reeves, Yutaka Takeo, André M. M. Sousa, Andres Moreno-De-Luca, Nenad Sestan, Stefan Weise, Tyrone DeSpenza, Fuchen Liu, Adam J. Kundishora, Ashley Dunbar, Benjamin C. Warf, Kristopher T. Kahle, Hannah Smith, Kartiga Selvaganesan, Seth L. Alper
Publikováno v:
Neurosurgery. 67
Autor:
Dhanpat Jain, Gülseren Evirgen Şahin, Kaela Drzewiecki, Joseph Brancale, Elif Karakoc-Aydiner, Buket Dalgic, Helen C. Su, Richard P. Lifton, Kadakkal Radhakrishnan, David E. Kleiner, Aysel Ünlüsoy Aksu, Jungmin Choi, Sinan Sari, Silvia Vilarinho, Junhui Zhang, Ahmet Ozen, Michael A. Leney-Greene, Safa Baris, Kasper Hoebe, Michael J. Lenardo, Michael Schmalz, João Pereira
Publikováno v:
The Journal of Experimental Medicine
Genomic analysis of families with unexplained portal hypertension reveals GIMAP5 as a critical regulator of liver sinusoidal endothelial cells and hepatic vascular homeostasis. This study identifies a novel genetic cause of portal hypertension and pr
Autor:
Ashima Gulati, Jungmin Choi, Sohan Punia, Richard P. Lifton, Shrikant Mane, Anna Rachel Gallagher, Sorin V. Fedeles, Murim Choi, Simone Sanna-Cherchi, Terry Watnick, Vicente E. Torres, York Pei, James R. Knight, Emily B. Huang, Ke Dong, Whitney Besse, Esa Tahvanainen, Pia Tahvanainen, Stefan Somlo
Publikováno v:
Journal of Clinical Investigation. 127:1772-1785
Dominantly inherited isolated polycystic liver disease (PCLD) consists of liver cysts that are radiologically and pathologically identical to those seen in autosomal dominant polycystic kidney disease, but without clinically relevant kidney cysts. Th
Autor:
Joseph Schlessinger, Alessandro D. Santin, Natalia Buza, Stefania Bellone, Richard P. Lifton, Jungmin Choi, Peter E. Schwartz
Publikováno v:
Clinical Cancer Research. 22:5682-5687
Purpose: The management of endometrial carcinoma no longer amenable to treatment with surgery or radiotherapy has not improved significantly with modern chemotherapy. Alternative therapeutic options are desperately needed. Experimental Design: We des
Autor:
Moses Lee, Serena Wong, Carlton L. Schwab, Emiliano Cocco, Laura Zanotti, Franco Odicino, Pei Hui, Federica Predolini, Charles M. Quick, Peter E. Schwartz, Chiara Romani, Elena Bonazzoli, Antonella Ravaggi, Sergio Pecorelli, Joseph Schlessinger, Stefania Bellone, Titus J. Boggon, Renata A. Tassi, Carla Donzelli, Richard P. Lifton, Amy L. Stiegler, Murim Choi, Roberto Angioli, Salvatore Lopez, Laura Ardighieri, Alessandro D. Santin, Paola Todeschini, Elisabetta Bandiera, Jungmin Choi, Jonathan Black, Mark Bi, Babak Edraki, Masoud Azodi, Fabio Facchetti, Kaya Bilguvar, Natalia Buza, Shrikant Mane, Siming Zhao, Elena Ratner, Durga Thakral, Corrado Terranova, Marcella Falchetti, Dan-Arin Silasi, Eliana Bignotti, Diana P. English, Luca Zammataro, Maysa M. Abu-Khalaf
Publikováno v:
Proceedings of the National Academy of Sciences. 113:12238-12243
Carcinosarcomas (CSs) of the uterus and ovary are highly aggressive neoplasms containing both carcinomatous and sarcomatous elements. We analyzed the mutational landscape of 68 uterine and ovarian CSs by whole-exome sequencing. We also performed mult
Autor:
Alessandro D. Santin, Elena Bonazzoli, Gulden Menderes, Weilai Dong, Franco Odicino, Ghanshyam Yadav, Antonella Ravaggi, Serena Wong, Paola Manara, Richard P. Lifton, Joseph Schlessinger, Babak Litkouhi, Chiara Romani, Valentina Zizioli, Laura Zanotti, Anna Bianchi, Chanhee Han, Gloria S. Huang, Elena Ratner, Charles Li, Francesca Pettinella, Burak Zeybek, Paola Todeschini, Masoud Azodi, Natalia Buza, Pei Hui, Peter E. Schwartz, Jungmin Choi, Sergio Pecorelli, Luca Zammataro, Eliana Bignotti, Dan-Arin Silasi, Francesco Riccio, Gary Altwerger, Salvatore Lopez, Laura Ardighieri, Stefania Bellone, Yang Yang-Hartwich, Aranzazu Manzano
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 116(2)
Ovarian cancer remains the most lethal gynecologic malignancy. We analyzed the mutational landscape of 64 primary, 41 metastatic, and 17 recurrent fresh-frozen tumors from 77 patients along with matched normal DNA, by whole-exome sequencing (WES). We
Autor:
Emad N. Eskandar, Charuta G. Furey, Adam J. Kundishora, Sierra B Conine, Geyu Zhou, Shrikant Mane, Shreyas Panchagnula, Kristopher T. Kahle, J. Marc Simard, Jungmin Choi, Murat Gunel, Emre Kiziltug, Jennifer Moliterno, Raymond F. Sekula, Qiongshi Lu, Francesc López-Giráldez, Christopher Gottschalk, Seth L. Alper, Fred G. Barker, Geneviève Brindle, Wei Liu, Weilai Dong, Carol Nelson-Williams, Ashley Dunbar, Shozeb Haider, Jason L. Gerrard, Richard P. Lifton, Mohamed Chahine, Michael C. Sierant, James R. Knight, August A Allocco, Amar H. Sheth, Phan Q. Duy, Boyang Li, Barira Islam, Jonathan Gaillard, Sheng Chih Jin, Christopher Castaldi, Xinyue Li, Stephen G. Waxman, Xue Zeng, Erin Loring, Jamie Hu, Louis Étienne Lorenzo, Yves De Koninck, Sulayman D. Dib-Hajj, Karine Bachand, Annie Castonguay, Agata K Sularz
Publikováno v:
iScience, Vol 23, Iss 10, Pp 101552-(2020)
iScience
iScience
Summary Trigeminal neuralgia (TN) is a common, debilitating neuropathic face pain syndrome often resistant to therapy. The familial clustering of TN cases suggests that genetic factors play a role in disease pathogenesis. However, no unbiased, large-