Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Marta Barisella"'
Autor:
Marco Fiore, Silva Ljevar, Sandro Pasquali, Daniele Morelli, Dario Callegaro, Roberta Sanfilippo, Marta Barisella, Claudia Sangalli, Rosalba Miceli, Alessandro Gronchi
Publikováno v:
Clinical Cancer Research. 29:614-620
Purpose: Inflammatory biomarkers and neutrophil-to-lymphocyte ratio (NLR) are associated with prognosis in several tumors. Data on sarcomas are limited, and insufficient on retroperitoneal sarcoma (RPS). Experimental Design: Patients with primary RPS
Autor:
Paolo G. Casali, Roberta Sanfilippo, M. D'Incalci, Maurizio Callari, Marta Barisella, Marina Meroni, Roberta Frapolli, Chiara Fabbroni, Ilaria Craparotta, Nicolò Panini, Laura Mannarino, Sergio Marchini, Sara Ballabio, Ezia Bello
Publikováno v:
Genomics. 113:3439-3448
Myxoid liposarcoma (MLPS) is a rare soft-tissue sarcoma characterised by the expression of FUS-DDIT3 chimera. Trabectedin has shown significant clinical anti-tumour activity against MLPS. To characterise the molecular mechanism of trabectedin sensiti
Autor:
Sandro Pasquali, Stefano Percio, Dario Callegaro, Silvia Martini, Alessia Beretta, Alessia Bertolotti, Silvia Brich, Paola Collini, Marta Barisella, Loris De Cecco, Viviana Vallacchi, Silvia Stacchiotti, Matteo Benelli, Alessandro Gronchi, Nadia Zaffaroni
Publikováno v:
Cancer Research. 83:2245-2245
This study aimed at unravelling whether WDLPS undergo a progressive evolution to DDLPS through analyzing the transcriptomic profile of retroperitoneal liposarcoma. In a contemporary retrospective series of primary retroperitoneal DDLPS and WDLPS (N=1
Autor:
Valentina Zuco, Sandro Pasquali, Monica Tortoreto, Stefano Percio, Valentina Doldi, Marta Barisella, Paola Collini, Gianpaolo Dagrada, Silvia Brich, Patrizia Gasparini, Marco Fiore, Michela Casanova, Anna Maria Frezza, Alessandro Gronchi, Silvia Stacchiotti, Andrea Ferrari, Nadia Zaffaroni
Publikováno v:
Cancer Research. 83:6726-6726
Desmoplastic small round cell tumor (DSRCT) is a ultra-rare pediatric scarcoma with poor overall survival. This tumor is dependent on the continued expression and activity of its pathognomonic molecular lesion, the EWS-WT1 transcription factor. DSRCT
Autor:
Jean-Yves Blay, Domenico Franco Merlo, Claudia Valverde, Antonella Brunello, Paola Collini, Salvatore Lorenzo Renne, Cleofé Romagosa, Antonio Lopez-Pousa, Joaquín Dopazo, Silvia Stacchiotti, Piero Picci, Angelo Paolo Dei Tos, Marco Gambarotti, Marta Barisella, Rafael Ramos, Paolo G. Casali, Antonio Gutierrez, Valérie Velasco, J. Martin-Broto, Silvia Bagué, David S. Moura, Nadia Hindi, Vittorio Quagliuolo, Giovanni Grignani, Maria Lopez-Alvarez, Alessandro Gronchi, Jean-Michel Coindre, Daniel Lopez-Lopez, Emanuela Palmerini, Luca Braglia
Publikováno v:
MOLECULAR CANCER THERAPEUTICS
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
instname
Digital.CSIC. Repositorio Institucional del CSIC
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
instname
Digital.CSIC. Repositorio Institucional del CSIC
MRP-1 is implicated in multidrug resistance and was described as prognostic in high-risk patients with soft-tissue sarcoma (STS) in a previous study. The current research aimed to validate MRP-1 prognostic/predictive value in localized sarcomas treat
Autor:
Marta Barisella, Marcella Tazzari, Alessandro De Vita, Alessia Bertolotti, Paola Collini, Toni Ibrahim, Viviana Vallacchi, Sandro Pasquali, Laura Bergamaschi, Chiara Castelli
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 7518, p 7518 (2021)
International Journal of Molecular Sciences
International Journal of Molecular Sciences
Soft tissue sarcomas (STSs) are a family of rare malignant tumors encompassing more than 80 histologies. Current therapies for metastatic STS, a condition that affects roughly half of patients, have limited efficacy, making innovative therapeutic str
Autor:
Sandro Pasquali, Stefano Percio, Dario Callegaro, Alessia Bertolotti, Silvia Brich, Marta Barisella, Paola Collini, Loris De Cecco, Roberta Sanfilippo, Anna Maria Frezza, Silvia Stacchiotti, Matteo Benelli, Nadia Zaffaroni, Alessandro Gronchi
Publikováno v:
Journal of Clinical Oncology. 40:e23520-e23520
e23520 Background: Retroperitoneal DDLPS is an aggressive tumor characterized by a WD component, morphologically similar to a WDLPS, and a DD component that drives patient prognosis. We aimed at unraveling whether WDLPS and DDLPS are distinct entitie
Autor:
Silvia Stacchiotti, Valentina Zuco, Anna Maria Frezza, Sandro Pasquali, Monica Tortoreto, Silvia Martini, Marta Barisella, Gianpaolo Dagrada, Paul Huang, Robin Lewis Jones, Paolo G Casali, Hugh Leonard, Alessandro Gronchi, Nadia Zaffaroni
Publikováno v:
Journal of Clinical Oncology. 40:11566-11566
11566 Background: EHE is an ultra-rare sarcoma marked by two specific fusions, WWTR1-CAMTA1 (̃90%) and YAP1-TFE3 (̃10%). The clinical course of EHE ranges from indolent to highly aggressive, often associated with systemic paraneoplastic symptoms. M
Autor:
William W. Tseng, Francesco Barretta, Stefano Radaelli, Chiara Colombo, Dario Callegaro, Marta Barisella, Carlo Morosi, Roberta Sanfilippo, Chiara Fabbroni, Silvia Stacchiotti, Marco Fiore, Alessandro Gronchi
Publikováno v:
Journal of Clinical Oncology. 40:e23545-e23545
e23545 Background: In comparison to the more common histologic subtypes of liposarcoma (e.g., well differentiated/dedifferentiated; myxoid round cell), pleomorphic liposarcoma (PLPS) is poorly understood but generally regarded as more aggressive, wit
Autor:
Sandro Pasquali, Monica Tortoreto, Calogero Lauricella, Gianpaolo Dagrada, Alessandro Gronchi, Roberta Sanfilippo, Silvia Stacchiotti, Marta Barisella, Chiara Colombo, Stefano Percio, Valentina Zuco, Mrinal M. Gounder, Paolo G. Casali, Rihan El Bezawy, Silvia Brich, Nadia Zaffaroni, Angelo Paolo Dei Tos
Publikováno v:
Journal of Experimental & Clinical Cancer Research : CR
Journal of Experimental & Clinical Cancer Research, Vol 40, Iss 1, Pp 1-12 (2021)
Journal of Experimental & Clinical Cancer Research, Vol 40, Iss 1, Pp 1-12 (2021)
Background Dedifferentiated liposarcoma (DDLPS), a tumor that lacks effective treatment strategies and is associated with poor outcomes, expresses amplified MDM2 in the presence of wild-type p53. MDM2 ubiquitination of p53 facilitates its XPO1-mediat