Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Mark P. Foster"'
Autor:
Ethan McClain, Sweta Desai, Amanda F. Cashen, Mark P. Foster, Peter Westervelt, Patrick Soon-Shiong, Michelle Becker-Hapak, Keith Stockerl-Goldstein, Jeffrey S. Miller, Miriam T. Jacobs, Mark A. Schroeder, Pamela Wong, Camille N. Abboud, Patrick Pence, Geoffrey L. Uy, Feng Gao, Claudio G. Brunstein, Melissa M. Berrien-Elliott, Meagan A. Jacoby, Iskra Pusic, Sarah Cooley, John F. DiPersio, Todd A. Fehniger
Publikováno v:
Blood. 139:1177-1183
Natural killer (NK) cells are a promising alternative to T cells for cancer immunotherapy. Adoptive therapies with allogeneic, cytokine-activated NK cells are being investigated in clinical trials. However, the optimal cytokine support after adoptive
Autor:
Pamela Wong, Jin-An Jiao, Timothy Schappe, Gilles M. Leclerc, Sweta Desai, Gabriela J. Muniz, Melissa M. Berrien-Elliott, Mark P. Foster, Lynne Marsala, Pallavi Chaturvedi, Carly Neal, Niraj Shrestha, Christian A. Echeverri, Xiaoyun Zhu, David A. Russler-Germain, Caitlin A. Prendes, Catherine M. Spanoudis, Todd A. Fehniger, Ethan McClain, Jack O. Egan, Michael J. Dee, Peter R. Rhode, Hing C. Wong, Jennifer Tran, Laritza L. Ramirez, Ryan P. Sullivan, Lijing You, Victor L. Gallo, Julia A. Wagner, Emily K. Jeng, Michelle Becker-Hapak, Patrick Pence
Publikováno v:
Cancer Immunol Res
Natural killer (NK) cells are a promising cellular therapy for cancer, with challenges in the field including persistence, functional activity, and tumor recognition. Briefly, priming blood NK cells with recombinant human (rh)IL-12, rhIL-15, and rhIL
Autor:
Amanda F. Cashen, Matthew L. Cooper, Carly Neal, Camille N. Abboud, Feng Gao, Sweta Desai, Melissa M. Berrien-Elliott, Michelle Becker-Hapak, Celia C. Cubitt, Timothy Schappe, Pamela Wong, Mark A. Schroeder, John F. DiPersio, Peter Westervelt, Julia A. Wagner, Jennifer A. Foltz, Meagan A. Jacoby, Natalia Jaeger, Iskra Pusic, Mark P. Foster, Geoffrey L. Uy, Todd A. Fehniger, Ethan McClain, Rizwan Romee, Keith Stockerl-Goldstein, Sridhar Nonavinkere Srivatsan
Publikováno v:
Cancer Discov
Natural killer (NK) cells are an emerging cancer cellular therapy and potent mediators of antitumor immunity. Cytokine-induced memory-like (ML) NK cellular therapy is safe and induces remissions in patients with acute myeloid leukemia (AML). However,
Autor:
Timothy Schappe, Pamela Wong, Marco L. Davila, Neha Mehta-Shah, Amanda F. Cashen, Wei Meng, John F. DiPersio, Matthew L. Cooper, Brad S. Kahl, Maximilian Schaettler, Jennifer Tran, Melissa M. Berrien-Elliott, Feng Gao, Lynne Marsala, Carly Neal, Nancy D. Marin, Miriam Y. Kim, Margery Gang, Nancy L. Bartlett, Todd A. Fehniger, Mark P. Foster
Publikováno v:
Blood
Natural killer (NK) cells are a promising cellular immunotherapy for cancer. Cytokine-induced memory-like (ML) NK cells differentiate after activation with interleukin-12 (IL-12), IL-15, and IL-18, exhibit potent antitumor responses, and safely induc
Autor:
Timothy Schappe, Miriam T. Jacobs, Todd A. Fehniger, Melissa M. Berrien-Elliott, Alice Zhou, Keenan J. Robbins, Bradley A. Krasnick, Celia C. Cubitt, Nancy D. Marin, Lynne Marsala, Christopher Wetzel, Michelle Becker-Hapak, Jennifer A. Foltz, Pamela Wong, Ryan C. Fields, Leah Conant, David A. Russler-Germain, Jennifer Tran, Mark P. Foster, Simon P. Goedegebuure
Publikováno v:
Clin Cancer Res
Purpose:Treatment of advanced melanoma is a clinical challenge. Natural killer (NK) cells are a promising cellular therapy for T cell–refractory cancers, but are frequently deficient or dysfunctional in patients with melanoma. Thus, new strategies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8496c86b6f83a236ec5ad44c4240a323
https://europepmc.org/articles/PMC8416927/
https://europepmc.org/articles/PMC8416927/
Autor:
Amanda F. Cashen, Nancy L. Bartlett, Brian T. Hess, Patrick Soon-Shiong, Obi L. Griffith, Matthew Mosior, Melissa M. Berrien-Elliott, Kristen McDaniels, Julia A. Wagner, Michelle Becker-Hapak, Malachi Griffith, Todd A. Fehniger, Ethan McClain, Veronika Bachanova, Allegra A. Petti, Narendranath Epperla, Amy Rock, John Lee, Mark P. Foster, Neha Mehta-Shah, Timothy Schappe, Feng Gao, Chaz Moreno, Jennifer A. Foltz, Nancy D. Marin, Brad S. Kahl
Publikováno v:
Clin Cancer Res
Purpose: N-803 is an IL15 receptor superagonist complex, designed to optimize in vivo persistence and trans-presentation, thereby activating and expanding natural killer (NK) cells and CD8+ T cells. Monoclonal antibodies (mAbs) direct Fc receptor–b
Autor:
Mark P. Foster, Rong Cai, Ana Karen Nunez Cortes, Yago Nieto, Vakul Mohanty, Melissa M. Berrien-Elliott, Sweta Desai, Joachim Koch, Michelle Becker-Hapak, Mecit Kaplan, Pamela Wong, May Daher, Natalie W. Fowlkes, Martin Treder, Luciana Garcia Melo, Wolfgang Fischer, Vandana Nandivada, Carly Neal, Luis Muniz-Feliciano, Li Li, Sonny Ang, Natalia Baran, Enli Liu, Elizabeth J. Shpall, Todd A. Fehniger, Yifei Shen, Richard E. Champlin, Ethan McClain, Mayela Mendt, Pinaki P. Banerjee, Francesca Lorraine Wei Inng Lim, Mayra Hernandez Sanabria, Oswaldo Keith Okamoto, Hila Shaim, Lucila Nassif Kerbauy, Katy Rezvani, Nancy D. Marin, Rafet Basar, Timothy Schappe, Ken Chen
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss Suppl 3 (2020)
Background Natural killer (NK) cells are a nascent cellular immunotherapy for hematologic malignancies. Target recognition of NK cell-resistant cancers remains a substantial barrier to broad application of NK cell therapy. One solution are bispecific
Autor:
Ayman Kabakibi, Niraj Shrestha, Alex Vessoni, Todd A. Fehniger, Michelle Becker-Hapak, Corey Johnson, Ethan McClain, Ken Chrobak, Mark P. Foster, Michael J. Dee, Malik Darwech, Ryan J. Sullivan, Alexander S. Hamil, Jennifer Govero, John Dean, You Zhou, Tom Leedom, Brunda Tumala, Carly Neal, Andrew Martens, Hing C. Wong, Melissa Berrien-Elliot, Mary Mathyer, Matthew L. Cooper
Publikováno v:
Journal for ImmunoTherapy of Cancer. 9:A200-A200
BackgroundAllogeneic Natural Killer (NK) cells are emerging as a safe and effective modality for the treatment of cancer, overcoming several limitations associated with adoptive T cell therapies. Cytokine induced memory-NK cells offer several advanta
Autor:
Wong Pamela, Melissa M. Berrien-Elliott, Tim Schappe, Todd A. Fehniger, Mark P. Foster, Margery Gang, Carly Neal, Lynne M Marsala, Wei M Meng, Maximilian M Schaettler, Nancy M Marin Agudelo
Publikováno v:
Blood. 134:869-869
NK cells are cytotoxic innate lymphoid cells that mediate anti-tumor responses and traffic to most tissues. NK cells activated briefly with IL-12, IL-15, and IL-18 differentiate into memory-like (ML) NK cells with enhanced anti-tumor effects, which h