Zobrazeno 1 - 10
of 134
pro vyhledávání: '"Lei Wei"'
Publikováno v:
Exp Ther Med
The diagnostic methods of conventional microbiological tests (CMTs) for severe community-acquired pneumonia (SCAP) may be too complicated or impossible to use in polymicrobial infections, and it may be difficult to identify unexpected pathogens. CMTs
Autor:
Sydney R. Grant, Spencer R. Rosario, Andrew D. Patentreger, Nico Shary, Megan E. Fitzgerald, Prashant K. Singh, Barbara A. Foster, Wendy J. Huss, Lei Wei, Gyorgy Paragh
Publikováno v:
Cancers; Volume 15; Issue 5; Pages: 1612
Mutations found in skin are acquired in specific patterns, clustering around mutation-prone genomic locations. The most mutation-prone genomic areas, mutation hotspots, first induce the growth of small cell clones in healthy skin. Mutations accumulat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0cb25ed97304e38f6c049b850361ac17
https://doi.org/10.21203/rs.3.rs-2216887/v1
https://doi.org/10.21203/rs.3.rs-2216887/v1
Autor:
Dongbo Xu, Qiang Cao, Li Wang, Jianmin Wang, Bo Xu, Kristopher Attwood, Lei Wei, Yue Wu, Gary J. Smith, Eriko Katsuta, Kazuaki Takabe, Gurkamal Chatta, Khurshid A. Guru, David W. Goodrich, Qiang J. Li
Publikováno v:
Mol Cancer Ther
Neoadjuvant chemotherapy (NAC) followed by radical cystectomy is the standard-of-care for patients with muscle-invasive bladder cancer (MIBC). Defects in nucleotide excision repair (NER) are associated with improved responses to NAC. Excision Repair
Autor:
Yao Xu, Jiaqian Li, Xiaoyue Shi, Xingwu Zhou, Yu Leo Lei, Xiaoqi Sun, Jutaek Nam, Jin Xu, Kai Han, James J. Moon, Kyung Soo Park, Yu Zhang, Lei Wei
Publikováno v:
Nature Nanotechnology. 16:1260-1270
Nutritional metal ions play critical roles in many important immune processes. Hence, the effective modulation of metal ions may open up new forms of immunotherapy, termed as metalloimmunotherapy. Here, we demonstrate a prototype of cancer metalloimm
Autor:
Lei Wei, Yuanhua Lei, Huasheng Fan, Donghua Zou, Beiquan Hu, Li Li, Xianlun Mo, Chao Qin, Feng Wei
Publikováno v:
Cancer Cell International, Vol 21, Iss 1, Pp 1-13 (2021)
Background Our previous bioinformatics-based study found that midkine (MDK) was associated with poor prognosis of glioblastoma (GBM). However, the mechanism of MDK in GBM remains elusive. Methods A public GBM-related dataset and GBM tissues from our
Publikováno v:
Anti-cancer drugs. 33(10)
Circular RNAs can act as critical regulators in the tumorigenesis and chemoresistance of ovarian cancer (OC). Herein, this work aimed to probe the function and mechanism of circ_0026123 in the cisplatin (DDP) resistance and progression of OC and its
Autor:
Yurong Song, Shaneen Baxter, Lisheng Dai, Chelsea Sanders, Holli Loomans-Kropp, Brandon Somerville, Ryan N. Baugher, Stephanie D. Mellott, Todd B. Young, Heidi E. Lawhorn, Teri M. Plona, Bingfang Xu, Lei Wei, Qiang Hu, Song Liu, Alan Hutson, Baktiar Karim, Simone Difilippantonio, Ligia Pinto, Matthias Kloor, Steven M. Lipkin, Shizuko Sei, Robert H. Shoemaker
Publikováno v:
Cancer Research. 83:6518-6518
DNA mismatch repair (MMR) genes (e.g., MLH1, MSH2, MSH6, PMS2, and EPCAM) play an important role in maintaining genomic stability during DNA replication and recombination. Deficiency in MMR resulting from mutations in these genes leads to mutations i
Publikováno v:
Materials Express. 10:1599-1606
We have designed a methodology to achieve treatment-actuated modifications in a tumor microenvironment by utilizing synergistic activity between two potential anticancer drugs. Dual drug delivery of Sorafenib (Sf) along with Cisplatin (Pt) exhibits a
Autor:
Weinan Yin, Ke Chen, Xiaoning Yuan, Yang Gao, Yihao Tian, Xiaolong Xu, Jingwei Zhang, Jinjing Xu, Wenbo Chen, Chunjiang He, Xin Dong, Lei Wei
Publikováno v:
Molecular Cancer, Vol 19, Iss 1, Pp 1-19 (2020)
Molecular Cancer
Molecular Cancer
Background Deregulated circular RNAs (circRNAs) are associated with the development of cancer and therapy resistance. However, functional research of circRNAs mostly focus on potential miRNA or protein binding and more potential regulation of circRNA
Autor:
Pengfei Han, Pengcui Li, Taoyu Chen, Chunfang Wang, Xianda Che, Bin Liang, Lei Wei, Jiangong Lu, Xiaochun Wei, Ziqi Hou
Publikováno v:
Molecular Medicine Reports
Indian hedgehog signaling molecule (Ihh) is known to play critical roles in chondrogenesis and cartilage development. However, it remains largely unknown how Ihh is regulated during the process. Previous studies suggest that Ihh plays an important re