Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Julia E. McGuinness"'
Autor:
Andreas Varkaris, Erika Hamilton, Jason Henry, Alexander I. Spira, Alison M. Schram, Julia E. McGuinness, Gege Tan, Xiaoyan Li, Tamieka Hunter, Ramin Samadani, Alison Timm, Djuro Karanovic, Vivek Subbiah, Cesar A. Perez
Publikováno v:
Cancer Research. 83:OT3-22
Background: Targeting constitutively active mutant kinases with selective small molecule inhibitors is a key therapeutic pillar of precision oncology. Phosphatidylinositol-4,5bisphosphate-3 kinase, catalytic subunit alpha (PIK3CA) mutations leading t
Autor:
Katherine D. Crew, Gauri Bhatkhande, Thomas Silverman, Jacquelyn Amenta, Tarsha Jones, Julia E. McGuinness, Jennie Mata, Ashlee Guzman, Ting He, Jill Dimond, Wei-Yann Tsai, Rita Kukafka
Publikováno v:
Cancer Prev Res (Phila)
Significant underutilization of breast cancer chemoprevention remains, despite guidelines stating that physicians should recommend chemoprevention with antiestrogen therapy to high-risk women. We randomized women, ages 35 to 75 years, who met high-ri
Autor:
Meghna S. Trivedi, Melissa K. Accordino, Fabio M. Iwamoto, Deanna Fisher, Lan Huynh, Kathleen Fenn, Julie Ann Mayer, Kevin Kalinsky, Dawn L. Hershman, Julia E. McGuinness, David Cieremans, Edgar V. Sales, Mary Welch, Margaux Wooster, Robbie Schultz, Shing Lee, Lauren Franks, Teri N. Kreisl, Andrew B. Lassman, Katherine D. Crew, Veena M. Singh, Aya Haggiagi
Publikováno v:
Clin Breast Cancer
Diagnosis of LM is limited by low sensitivity of cerebrospinal fluid (CSF) cytopathology. Detecting tumor cells in CSF (CSF-TCs) might be more sensitive. We evaluated if CNSide (CNSide), a novel assay for tumor cell detection in CSF, can detect CSF-T
Autor:
Alissa Michel, Vicky Ro, Julia E. McGuinness, Simukayi Mutasa, Mary Beth Terry, Parisa Tehranifar, Benjamin May, Richard Ha, Katherine D. Crew
Publikováno v:
Breast Cancer Research and Treatment.
Autor:
Julia E. McGuinness, Vicky Ro, Simukayi Mutasa, Samuel Pan, Jianhua Hu, Meghna S. Trivedi, Melissa K. Accordino, Kevin Kalinsky, Dawn L. Hershman, Richard S. Ha, Katherine D. Crew
Publikováno v:
Breast Cancer Research and Treatment. 194:35-47
Publikováno v:
Cancer Research. 82:P2-10
Background: Accurate assessment of a woman’s individualized breast cancer risk is necessary to inform shared decision-making regarding screening and risk-reducing strategies. Recently, deep learning techniques, including convolutional neural networ
Autor:
Katherine D. Crew, Melissa K. Accordino, Alessandro Marone, Shing M. Lee, Lauren Franks, Andreas H. Hielscher, Kevin Kalinsky, Julia E. McGuinness, Dawn L. Hershman, Mirella L. Altoe, Meghna S. Trivedi, Mariella Tejada, Hyun K. Kim
Publikováno v:
Breast Cancer Research and Treatment. 189:297-304
Diffuse optical tomography breast imaging system (DOTBIS) non-invasively measures tissue concentration of hemoglobin, which is a potential biomarker of short-term response to neoadjuvant chemotherapy. We evaluated whether DOTBIS-derived measurements
Publikováno v:
Breast Cancer Research and Treatment. 189:1-13
While checkpoint inhibitors have been approved in patients with newly metastatic PDL1-positive triple negative breast cancer, similar clinical benefit with immunotherapy alone or in combination with chemotherapy has not been observed in patients with
Publikováno v:
Cancer Research. 83:PD16-02
Introduction: Digital breast tomosynthesis (DBT) is increasingly utilized in breast cancer screening, including among women at high risk for breast cancer. While there is a lack of rigorous data from randomized controlled trials demonstrating superio
Autor:
Luisa Nilan, Jacquelyn N. Amenta, Julia E. McGuinness, Rita Kukafka, Katherine D. Crew, Kehinde Lawal
Publikováno v:
Cancer Research. 83:P3-03
Background: Chemoprevention with selective estrogen receptor modulators (SERMs) and aromatase inhibitors (AIs) has been shown in randomized controlled trials to decrease breast cancer incidence by 50-65% among women at high risk for breast cancer. Ho