Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Juan Dong"'
Publikováno v:
Experimental and Therapeutic Medicine. 23
The microcirculation is correlated with the prognosis of patients with cardiac arrest and changes after resuscitation. In the present study, the effects of anisodamine hydrobromide (AH) on microcirculation was investigated and its potential mechanism
Autor:
Yanqing Wu, Peng Duan, Yujiao Wen, Jin Zhang, Xiaoli Wang, Juan Dong, Qiang Zhao, Shenglei Feng, Chunyu Lv, Yang Guo, Satoshi H. Namekawa, Shuiqiao Yuan
Publikováno v:
Cell death & disease, vol 13, iss 4
Sertoli cells (SCs) support and nourish germ cells (GCs) through their crosstalk during spermatogenesis. However, the underlying epigenetic mechanism that ensures SCs’ functions in this process remains unclear. Here, we report that UHRF1, a critica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48da00dee4b0dc650d4ef163e14b7cfe
https://escholarship.org/uc/item/8766n5rt
https://escholarship.org/uc/item/8766n5rt
Autor:
Jian Li, Jun Zhang, Yanqiao Zhang, Haibo Qiu, Yanbing Zhou, Yongjian Zhou, Xinhua Zhang, Ye Zhou, Yuping Zhu, Yong Li, Ming Wang, Kuntang Shen, Kaixiong Tao, Xin Wu, Haijiang Wang, Bo Zhang, Jiayu Ling, Yingjiang Ye, Juan Dong, Lin Shen
Publikováno v:
Journal of Clinical Oncology. 41:803-803
803 Background: Ripretinib is a switch-control tyrosine kinase inhibitor approved for the fourth-line therapy for GIST. In the INTRIGUE study (NCT03673501), ripretinib as second-line (2L) treatment demonstrated similar progression-free survival (PFS)
Publikováno v:
PLoS genetics. 18(6)
The regulation of glycometabolism homeostasis is vital to maintain health and development of animal and humans; however, the molecular mechanisms by which organisms regulate the glucose metabolism homeostasis from a feeding state switching to a non-f
Autor:
Jian Li, Shirong Cai, Yongjian Zhou, Jun Zhang, Ye Zhou, Hui Cao, Xin Wu, Yanhong Deng, Zhao Huang, Juan Dong, Lin Shen
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 28(16)
Purpose: This is a phase II multicenter, single-arm, open-label study assessing the efficacy, safety, and pharmacokinetics (PK) of ripretinib in Chinese patients with advanced gastrointestinal stromal tumor (GIST) as a fourth- or later-line therapy.
Autor:
Zhi Yu Han, Ping Liang, Ning Hai, Jie Yu, Fang Yi Liu, Xiao Liang Lin, Jing Zhang, Xue Juan Dong
Publikováno v:
International Journal of Hyperthermia, Vol 37, Iss 1, Pp 151-156 (2020)
Objectives To prospectively compare the effectiveness and safety of percutaneous microwave ablation (PMWA) and ultrasound-guided radiofrequency ablation (USgRFA) for treating symptomatic uterine adenomyosis. Methods One hundred and thirty-three women
Autor:
Hieu Ta, Demin Wang, Subramaniam Malarkannan, Marc S. Ernstoff, Wenwen Xu, Juan Zhou, Michael F. Olson, Juan Dong, Halli E. Miller, Li Wang, Yongwei Zheng, Ying Yuan, Kamalakannan Rajasekaran
Publikováno v:
Cancer Immunology Research. 7:1497-1510
Immune-checkpoint protein V-domain immunoglobulin suppressor of T-cell activation (VISTA) controls antitumor immunity and is a valuable target for cancer immunotherapy. This study identified a role of VISTA in regulating Toll-like receptor (TLR) sign
Autor:
Bo Zhao, Zhengyao Shao, Likai Wang, Fan Zhang, Daveraj Chakravarty, Wei Zong, Juan Dong, Liang Song, Hong Qiao
Publikováno v:
PLOS Genetics. 18:e1010473
Histone acetylation has been shown to involve in stress responses. However, the detailed molecular mechanisms that how histone deacetylases and transcription factors function in drought stress response remain to be understood. In this research, we sh
501 VISTA regulates the differentiation and suppressive function of myeloid-derived suppressor cells
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss Suppl 3 (2020)
Background V-domain immunoglobulin suppressor of T cell activation (VISTA) is a B7 family inhibitory immune checkpoint protein and is highly expressed on myeloid cells and T cells.1 VISTA acts as both an inhibitory ligand when expressed on antigen-pr
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss Suppl 3 (2020)
Background Cancer immunotherapies have proven, over the last decade, to be of extreme importance for long term survival of patients. Specifically, immune checkpoint inhibitors such as anti-CTLA-4 and anti-PD-1/PD-L1 have had tremendous clinical succe