Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Jiawei Guan"'
Publikováno v:
Biomedicine & Pharmacotherapy. 94:165-168
PTEN is a tumor suppressor gene well characterized as a phosphatase. However, more evidences demonstrate PTEN functions in DNA repair independent of its phosphatase activity, which affects the efficacy of DNA damage anti-tumoral drugs in treating can
Publikováno v:
Oncology Letters. 14:4965-4970
Triptolide is the primary compound isolated from Tripterygium wilfordii, which has been reported to inhibit nucleotide excision repair as well as exhibit anti-inflammatory and antitumor activities. However, the action of triptolide in DNA breaks rema
Publikováno v:
Biochimica et biophysica acta. 1863(12)
PTEN is a tumor suppressor gene characterized as a phosphatase that antagonizes the phosphatidylinositol 3-kinase signaling pathway in the cytoplasm. Nuclear PTEN plays roles in chromosomal stability, in which the double-strand breaks (DSB) repair me