Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Jean-Baptiste, Marchand"'
Autor:
Jean-Baptiste Marchand, Elodie Pintado, Marshall Dunlop, Christelle Remy, Patricia Kleinpeter, Shirley Shön, Fend Laetitia, Renée Brandely, Delphine Suhner, Eline Winter, Nathalie Silvestre, Claire Huguet, Peter Fitzgerald, Eric Quéméneur
Publikováno v:
Cancer Research. 83:1885-1885
Background: Single domain antibodies (sdAbs) isolated after immunization of camelids are particularly attractive formats for their high modularity and small size allowing a better diffusion into tumors. However, the short in vivo half-life of sdAbs,
Autor:
Monika Semmrich, Jean-Baptiste Marchand, Laetitia Fend, Matilda Rehn, Christelle Remy, Petra Holmkvist, Nathalie Silvestre, Carolin Svensson, Patricia Kleinpeter, Jules Deforges, Fred Junghus, Kirstie L Cleary, Mimoza Bodén, Linda Mårtensson, Johann Foloppe, Ingrid Teige, Eric Quéméneur, Björn Frendéus
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 1 (2022)
BackgroundImmune checkpoint blockade (ICB) is a clinically proven concept to treat cancer. Still, a majority of patients with cancer including those with poorly immune infiltrated ‘cold’ tumors are resistant to currently available ICB therapies.
Autor:
Jean-Baptiste Marchand, Monika Semmrich, Christelle Ziller, Matilda Rehn, Laetitia Fend, Petra Holmkvist, Nathalie Silvestre, Carolin Svensson, Kleinpeter Patricia, Jules Deforges, Fred Junghus, Linda Mårtensson, Johann Foloppe, Ingrid Teige, Björn Frendéus, Eric Quéméneur
Publikováno v:
Cancer Research. 82:3567-3567
Background Immune checkpoint blockade (ICB) is a clinically proven concept to treat cancer. Still, a majority of cancer patients including those with poorly immune infiltrated “cold” tumors are resistant to currently available ICB therapies. Onco
Autor:
Eric Quemeneur, Jean-Baptiste Marchand, Ingrid Teige, Matilda Rehn, Linda Mårtensson, Monika Semmrich, Laetitia Fend, Johann Foloppe, Nathalie Silvestre, Björn Frendéus
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss Suppl 3 (2020)
Background Checkpoint inhibitor antibodies have improved survival in a variety of cancers, however, a great unmet need remains since only a small fraction of patients responds. Reasons for lack of efficacy are believed to include lack of tumor infilt
Autor:
Christelle Remy-Ziller, Fred Junghus, Johann Foloppe, Ingrid Teige, Petra Holmkvist, Patricia Kleinpeter, Carolin Svensson, Björn Frendéus, Matilda Rehn, Monika Semmrich, Jules Deforges, Eric Quéméneur, Jean-Baptiste Marchand, Linda Mårtensson, Nathalie Silvestre, Laetitia Fend
Publikováno v:
Journal for ImmunoTherapy of Cancer. 9:A777-A777
BackgroundImmune checkpoint blockade (ICB) is a clinically proven concept to treat cancer. Still, a majority of cancer patients including those with poorly immune infiltrated “cold” tumors are resistant to currently available ICB therapies. CTLA-
Autor:
Johann Foloppe, Ingrid Teige, Nathalie Silvestre, Matilda Rehn, Eric Quéméneur, Jean-Baptiste Marchand, Laetitia Fend, Björn Frendéus, Monika Semmrich, Linda Mårtensson
Publikováno v:
Cancer Research. 80:5602-5602
Oncolytic virotherapy is a clinically validated class of immune modulatory drugs with activity in solid cancer. The mode of action of armed oncolytic Vaccinia viruses (oVV) includes cell death induction following selective replication in tumor cells,
Autor:
Patricia Kleinpeter, Laetitia Fend, Dominique Villeval, Renée Brandely, Christine Thioudellet, Véronique Koerper, Jean-Baptiste Marchand, Nathalie Silvestre, Karola Rittner, Michel Geist, Nathalie Sfrontato, Eric Quéméneur, Laurence Zitvogel, Philippe Erbs, Xavier Préville
Publikováno v:
Cancer Research. 76:2352-2352
We report here the successful vectorization of a hamster monoclonal IgG (namely J43) recognizing the murine Programmed cell death-1 (mPD-1) in Western Reserve (WR) oncolytic vaccinia virus. Three forms of mPD-1 binders have been inserted in the virus
Autor:
Benoît Grellier, Ronald Rooke, Thierry Menguy, Sandrine Cochin, Jean-Baptiste Marchand, Christine Thioudellet, Michel Geist, Jean-Yves Bonnefoy, Vanessa Duong, Carine Reymann, Hélène Haegel, Xavier Préville, Rémy Hallet, Christelle Ziller-Remy, Luc Barraud
Publikováno v:
Cancer Research. 75:288-288
Cancer progression has been associated with the presence of tumor-associated M2-type macrophages (M2-TAMs) able to inhibit anti-tumor immune responses, stimulate neo-angiogenesis and facilitate metastasis. Colony-stimulating factor-1 (CSF-1, M-CSF) i
Autor:
Nathalie Accart, Ronald Rooke, Jean-Baptiste Marchand, Fabrice Le Pogam, Hélène Haegel, Philippe Slos, Jean-Yves Bonnefoy, Carine Reymann, Laetitia Fend, Sylvie Fournel, Jacqueline Kintz, Thierry Menguy, Sandrine Cochin, Xavier Préville
Publikováno v:
PLoS ONE
PLoS ONE, Vol 8, Iss 9, p e73310 (2013)
PLoS ONE, Vol 8, Iss 9, p e73310 (2013)
Tumor progression is promoted by Tumor-Associated Macrophages (TAMs) and metastasis-induced bone destruction by osteoclasts. Both myeloid cell types depend on the CD115-CSF-1 pathway for their differentiation and function. We used 3 different mouse c