Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Hannu Koistinen"'
Autor:
Timo‐Pekka K. Lehto, Ruusu‐Maaria Kovanen, Susanna Lintula, Adrian Malén, Carolin Stürenberg, Andrew Erickson, Olli‐Pekka Pulkka, Ulf‐Håkan Stenman, Eleftherios P. Diamandis, Antti Rannikko, Tuomas Mirtti, Hannu Koistinen
Publikováno v:
International Journal of Cancer.
Autor:
Michael Jeltsch, Kenny Mattonet, Ulf-Håkan Stenman, Eunice Wairimu Maina, Kari Alitalo, Sawan Kumar Jha, Hannu Koistinen, Ewa Chronowska, Khushbu Rauniyar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4862ce31f2f18a7421cf1c6f79e577c5
https://doi.org/10.7554/elife.44478.034
https://doi.org/10.7554/elife.44478.034
Autor:
Janaththani Panchadsaram, Kerry DeVoss, Ulf-Håkan Stenman, Emily Wilson, Robert J. Klein, Carson R. Stephens, Hans Lilja, Mark N. Brook, Srilakshmi Srinivasan, Judith A. Clements, Jyotsna Batra, Ashley M. Buckle, Hannu Koistinen
Publikováno v:
Srinivasan, S, Stephens, C, Wilson, E, Panchadsaram, J, DeVoss, K, Koistinen, H, Stenman, U-H, Brook, M N, Buckle, A M, Klein, R J, Lilja, H, Clements, J, Batra, J & The PRACTICAL Consortium 2019, ' Prostate Cancer Risk-Associated Single-Nucleotide Polymorphism Affects Prostate-Specific Antigen Glycosylation and Its Function ', Clinical Chemistry, vol. 65, no. 1, pp. e1-e9 . https://doi.org/10.1373/clinchem.2018.295790
BACKGROUND Genetic association studies have reported single-nucleotide polymorphisms (SNPs) at chromosome 19q13.3 to be associated with prostate cancer (PCa) risk. Recently, the rs61752561 SNP (Asp84Asn substitution) in exon 3 of the kallikrein-relat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56e38f3891a1d9f4d70b62eba64e4635
https://pure.au.dk/portal/da/publications/prostate-cancer-riskassociated-singlenucleotide-polymorphism-affects-prostatespecific-antigen-glycosylation-and-its-function(aa037b18-622b-469d-82be-973bd78188c7).html
https://pure.au.dk/portal/da/publications/prostate-cancer-riskassociated-singlenucleotide-polymorphism-affects-prostatespecific-antigen-glycosylation-and-its-function(aa037b18-622b-469d-82be-973bd78188c7).html
Publikováno v:
Clinical Chemistry. 62:449-457
BACKGROUNDTumor-associated trypsin inhibitor (TATI) was originally isolated from the urine of a patient with ovarian cancer. It was later shown to be produced by many other tumors and several normal tissues. It had earlier been isolated from the panc
Autor:
Ulf-Håkan Stenman, Kati Räsänen, Hannu Koistinen, Elina Lehtinen, Teijo Kuopio, Kristiina Nokelainen, Outi Itkonen, Laura Hautala
Publikováno v:
Molecular Carcinogenesis. 55:2010-2023
Inflammation promotes colorectal cancer (CRC) tumorigenesis, but the underlying molecular mechanisms are still being uncovered. Proinflammatory cytokine interleukin-6 (IL-6) stimulates survival signaling in CRC; inflammatory signals also regulate pro
Autor:
Maria Jäntti, Raimo K. Tuominen, Hannu Koistinen, Ilari Tarvainen, Kati Räsänen, Virpi Talman
Publikováno v:
FEBS Open Bio
Prostate cancer is one of the most common cancers in men. Although it has a relatively high 5-year survival rate, development of resistance to standard androgen-deprivation therapy is a significant clinical problem. Therefore, novel therapeutic strat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0ed5b0bf7763f2b761c60ac9f71047f
http://hdl.handle.net/10138/235487
http://hdl.handle.net/10138/235487
Publikováno v:
Atlas of Genetics and Cytogenetics in Oncology and Haematology.
Publikováno v:
The Prostate. 72:1588-1594
BACKGROUND Proteolytically active prostate-specific antigen (PSA or kallikrein-related peptidase 3, KLK3) has been shown to exert antiangiogenic properties. High levels of PSA in prostatic tumors may thus slow down cancer progression by inhibiting an
Autor:
Hannu Koistinen, Kaarina Sivonen, David P. Fewer, Matthias Nees, Ulf-Håkan Stenman, Matti Wahlsten, Muhammad N. Ahmed
Publikováno v:
Cancer Research. 78:2679-2679
Trypsin-3 is a highly active protease that has recently been identified as a potential therapeutic target for the reduction of tumor growth and metastasis in prostate, breast and pancreatic cancers. Current trypsin inhibitors typically inhibit a broa
Autor:
Päivi Heikkilä, Riitta Koistinen, Heli Nevanlinna, Tuomas Heikkinen, Hannu Koistinen, Laura Hautala, Kristiina Aittomäki, Dario Greco, Carl Blomqvist
Publikováno v:
Breast Cancer Research and Treatment. 128:85-95
Glycodelin (encoded by PAEP gene) is a secreted lipocalin protein mainly expressed in reproductive tissues, but also in several tumour types. In the breast, glycodelin is expressed both in normal epithelial and cancerous tissue. To investigate the as