Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Donghwa Kim"'
Autor:
Young-Mi Kim, Hyen Joo Park, Donghwa Kim, Woong Sub Byun, Eun Seo Bae, Sang Kook Lee, Young-Won Chin
Publikováno v:
Biomolecules & Therapeutics
Colorectal cancer (CRC) is one of the most malignant type of cancers and its incidence is steadily increasing, due to life style factors that include western diet. Abnormal activation of canonical Wnt/β-catenin signaling pathway plays an important r
Autor:
Jeeyeon Lee, Sunghwa Kim, Hyeung-geun Park, Won Kyung Kim, Hwa-Jin Chung, Kyungkuk Jang, Donghwa Kim, Woong Sub Byun, Eun Seo Bae, Sunghyouk Park, Sang Kook Lee, Han Sun Kim, Hae Ju Han
Publikováno v:
Molecular Therapy: Oncolytics, Vol 15, Iss, Pp 140-152 (2019)
Molecular Therapy Oncolytics
Molecular Therapy Oncolytics
Triple-negative breast cancer (TNBC) is the most intractable cancer in women with a high risk of metastasis. While hyper-methylation of histone H3 catalyzed by disruptor of telomeric silencing 1-like (DOT1L), a specific methyltransferase for histone
Autor:
Thi-Thu-Trang Luu, Ruoci Hu, Donghwa Kim, Sang Kook Lee, Cai Yi Wang, Ji Yun Lee, Hee-Juhn Park
Publikováno v:
Journal of Natural Products. 82:3140-3149
A flavonoid glycoside, quercitrin (1), and two phenylpropanoyl sucrose derivatives, vanicoside B (2) and lapathoside C (3), were isolated for the first time from the herb Persicaria dissitiflora. Vanicoside B (2) exhibited antiproliferative activity
Autor:
Sourav Bandyopadhyay, Donghwa Kim
Publikováno v:
EBioMedicine, Vol 65, Iss, Pp 103257-(2021)
EBioMedicine
EBioMedicine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8389468ee8b97fb22e9f523fbb01b4d4
https://escholarship.org/uc/item/1kt1n6rp
https://escholarship.org/uc/item/1kt1n6rp
Autor:
Hyen Joo Park, Sunghyouk Park, Donghwa Kim, Yong Jin An, Duc-Hiep Bach, Sang Kook Lee, Thi-Thu-Trang Luu
Publikováno v:
Molecular Therapy. Nucleic Acids
Molecular Therapy: Nucleic Acids, Vol 12, Iss, Pp 817-828 (2018)
Molecular Therapy: Nucleic Acids, Vol 12, Iss, Pp 817-828 (2018)
Lung cancer is the leading cause of cancer-associated deaths worldwide. In particular, non-small-cell lung cancer (NSCLC) cells harboring epidermal growth factor receptor (EGFR) mutations are associated with resistance development of EGFR tyrosine ki
Autor:
Jianyu Liu, Xiao-Sheng Yang, Ji-Young Hong, Sang Kook Lee, Donghwa Kim, Daoping Wang, Yongnan Xu, Huai-Wei Ding, Yanhua Fan
Publikováno v:
Pharmacological research. 160
EPHB6 is a metastasis inhibitory gene that is frequently decreased or deficiency in non-small cell lung cancer (NSCLC), which contributed to the subsequent development of distant metastasis. These suggested the possibility that reactivation of EPHB6
Publikováno v:
Anticancer research. 40(4)
Background/aim The resistance to epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs), such as gefitinib or erlotinib, is considered a major challenge in the treatment of patients with non-small cell lung cancer (NSCLC). Herein, we
Autor:
Yoosik Kim, Mark Borris D. Aldonza, Jinju Han, Stephanie Tan, Monica Celine Prayogo, Minseok Lee, Ji-Young Hong, Sang Kook Lee, Donghwa Kim, Han Suk Ryu, Sung Gap Im, Seung Jung Yu, Dayeon Kim, Jayoung Ku
Publikováno v:
Science Advances
Paclitaxel failure promotes collateral resistance to EGFR-targeted therapy by adaptive rewiring of the cellular stress response.
Secondary drug resistance stems from dynamic clonal evolution during the development of a prior primary resistance.
Secondary drug resistance stems from dynamic clonal evolution during the development of a prior primary resistance.
Publikováno v:
Natural Products for Cancer Chemoprevention ISBN: 9783030398545
Receptor tyrosine kinases (RTKs) are cell membrane-anchored receptors that bind to growth factors, cytokines, and hormones for signal transduction and regulate various signaling cascades. Among the diverse RTKs, epidermal growth factor receptor (EGFR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::21714c27d4b2c95456c6ad8b3502fe9e
https://doi.org/10.1007/978-3-030-39855-2_14
https://doi.org/10.1007/978-3-030-39855-2_14
Autor:
Soonbum Kwon, Ji-Young Hong, Sang Kook Lee, Won Kyung Kim, Jeeyeon Lee, Nirmal Rajasekaran, Donghwa Kim, Hye-Jung Lee, Young Kee Shin, Duc-Hiep Bach, Thi-Thu-Trang Luu, Yanhua Fan, Song Yi Bae
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 11, Iss C, Pp 455-467 (2018)
Molecular Therapy. Nucleic Acids
Molecular Therapy. Nucleic Acids
Epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs) are used clinically as target therapies for lung cancer patients, but the occurrence of acquired drug resistance limits their efficacy. Nicotinamide N-methyltransferase (NNMT), a