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pro vyhledávání: '"Chang-Xian Chen"'
MiR-25-3p Serves as an Oncogenic MicroRNA by Downregulating the Expression of Merlin in Osteosarcoma
Autor:
Jia-Wen Wang, Zhao-Ke Wu, Hui-Yong Yang, Yun Jiang, Si-da Wei, Qing-Xin Guo, Chang-Xian Chen, Hua-Chun Rao
Publikováno v:
Cancer Management and Research. 12:8989-9001
Purpose Moesin-ezrin-radixin-like protein (Merlin) has been identified as a tumor suppressor in several types of cancers. However, the biological function of Merlin in osteosarcoma remains unclear. MicroRNAs (miRNAs) can influence cancer progression
Publikováno v:
Medicine. 98:e14588
Objective:DNA methylation is the earliest and most studied epigenetic modification in cancer. The literature reported that the abnormal methylation level of multiple genes was associated with poor prognosis in ovarian cancer. However, due to a small