Zobrazeno 1 - 10
of 70
pro vyhledávání: '"Bo Hong"'
Autor:
Bo Hong, Chen Ding, Ruiping Du, Feilong Sun, Kai Li, Jian Qi, Wen Zhong, Wei Wang, Qiuyan Sun, Qingmei Deng, Hongzhi Wang, Jinfu Nie
Publikováno v:
Anti-Cancer Agents in Medicinal Chemistry. 23
Introduction: Among gynecological cancers, ovarian cancer has a high mortality rate. Cisplatin-based chemotherapy is commonly used for the treatment of ovarian cancer. However, the clinical efficacy of cisplatin in ovarian cancer is limited due to th
Publikováno v:
BMC Cancer. 22
Background As a negative co-stimulatory molecule of the B7 family, B7-H4 has recently attracted increased attention. However, the clinical value of B7-H4 in colorectal cancer (CRC) remains controversial and requires further investigation. This study
Autor:
Jie Ji, Hongzhi Wang, Huanhu Zhang, Dahai Zhao, Shujie Wang, Rui Tao, Bo Hong, Jinfu Nie, Jian Qi, Ruifang Sun, Xiaopeng Zhang, Yanzhe Liu, Qingmei Deng
Publikováno v:
Cancer Science
Cell‐free methylated DNA immunoprecipitation and high‐throughput sequencing (cfMeDIP‐seq) is a new bisulfite‐free technique, which can detect the whole‐genome methylation of blood cell‐free DNA (cfDNA). Using this technique, we identified
Publikováno v:
Translational Cancer Research
Wilms tumor is the most common pediatric abdominal solid tumor, and its treatment has been a focus of research. For now, the 5-year survival rate of children with Wilms tumor is about 90%. It is difficult to make further progress simply by the improv
Autor:
Hong Li, Bo Hong, Chen Ding, Xiaoli Liu, Vivian Wai Yan Lui, Ke Deng, Xiao-tong Lv, Wenchu Lin, Wen-hao Shi, Yan-ping Yin
Publikováno v:
Acta Pharmacol Sin
Proteasome inhibitors, bortezomib (BTZ), and carfilzomib (CFZ) are approved drugs for hematological malignancies, but lack anticancer activities against most solid tumors. Small cell lung cancer (SCLC) is a very aggressive neuroendocrine carcinoma of
Autor:
Jinman Fang, Jie Fang, Bo Hong, Qingmei Deng, Jinfu Nie, Hongzhi Wang, Weimin Wang, Xingxing Huo, Fei Li, Xiaojun Sun, Lin Lin, Jian Qi, Huanzhong Wang, Feifei Li, Shujie Wang, Qiuyan Sun
Publikováno v:
Translational Cancer Research
Background Tumor cells undergoing epithelial-mesenchymal transition (EMT) display enhanced ability to enter the circulation, thereby being major source of circulating tumor cells (CTCs). In this study, we aimed to better understand the roles of CTC u
Publikováno v:
Open Medicine
Open Medicine, Vol 15, Iss 1, Pp 882-889 (2020)
Open Medicine, Vol 15, Iss 1, Pp 882-889 (2020)
MicroRNA (miR/miRNA) expression disorders play a crucial role in the development of gastric cancer (GC). Increasing evidence has indicated that miRNAs participate in the process of numerous cancers. Previous research has demonstrated that miR-300 act
Publikováno v:
Journal of cancer research and clinical oncology. 148(12)
Ewing sarcoma (EwS) is an aggressive malignant neoplasm composed of small round cells. The heterogeneity and developmental trajectories of EwS are uncertain.Single-cell RNA sequencing was performed on 4 EwS tumor tissue samples, and 3 transcriptional
Autor:
Hong Li, Wenchu Lin, Lailing Li, Bo Hong, Dandan Han, Wulin Shan, Dan Li, Ming Li, Yang Zhang, Jinglu Zou
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-9 (2020)
Scientific Reports
Scientific Reports
miRNAs have been reported to be stably detectable in plasma and to function as potent biomarkers in multiple cancers. The study aimed to evaluate the expression of candidate circulating miRNAs in patients with small cell lung cancer (SCLC) to identif
Autor:
Tingting Liang, Ping Zhao, Xiao Zhang, Xuedan Han, Bo Hong, Lingsheng Kong, Huanxian Chang, Liyan Liu
Publikováno v:
Experimental and therapeutic medicine. 23(6)
Forkhead box A1 (FOXA1) plays an important role in the central nervous system, and its loss can lead to the downregulation of tyrosine hydroxylase, which directly affects the synthesis of dopamine, thus leading to Parkinson's disease (PD). The presen