Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Amer H. Zureikat"'
Autor:
Amer H. Zureikat, Ibrahim Nassour, David L Bartlett, Annissa Desilva, Lance A. Liotta, Aatur D. Singhi, Virginia Espina, Alessandro Paniccia, Samer AlMasri, Nathan Bahary, Brian A. Boone, Herbert J. Zeh, Patricia Loughran, Michael T. Lotze, Mazen S. Zenati
Publikováno v:
Cancer Medicine
Cancer Medicine, Vol 10, Iss 20, Pp 7233-7241 (2021)
Cancer Medicine, Vol 10, Iss 20, Pp 7233-7241 (2021)
Introduction Preoperative autophagy inhibition with hydroxychloroquine (HCQ) in combination with gemcitabine in pancreatic adenocarcinoma (PDAC) has been shown to be safe and effective in inducing a serum biomarker response and increase resection rat
Autor:
Alessandro Paniccia, Derek Barclay, Yoram Vodovotz, Jacob C. Hodges, Michael T. Lotze, Pranav Murthy, Amer H. Zureikat, Brian A. Boone, Randall E. Brand, Ruben Zamora, Kenneth K. Lee, Asmita Chopra, Richard L. Simmons
Publikováno v:
J Immunother
Despite its increased application in pancreatic ductal adenocarcinoma (PDAC), complete response to neoadjuvant therapy (NAT) is rare. Given the critical role of host immunity in regulating cancer, we sought to correlate baseline inflammatory profiles
Autor:
Michael J. Pishvaian, Amer H. Zureikat, Charles D. Lopez, Kenneth Meredith, Emmanuel E. Zervos, Hassan Hatoum, Ki Y. Chung, Daniel James Berg, Antonio Ucar, Ripal T Gandhi, Reza Nazemzadeh, Nainesh Parikh, Paula M. Novelli, Brian Kouri, Christopher Laing, Brian A. Boone, Thor Johnson, Susan Elaine Bates, Ramtin Agah, Karyn A. Goodman
Publikováno v:
Journal of Clinical Oncology. 41:TPS773-TPS773
TPS773 Background: Prognosis for locally advanced pancreatic cancer (LAPC) remains dismal even with advances in cancer therapy. Beyond systemic therapies, local disease control is important in these patients. Local double balloon mediated delivery of
Autor:
Karyn A. Goodman, Michael J. Pishvaian, Charles D. Lopez, Kenneth Meredith, Emmanuel E. Zervos, Hassan Hatoum, Ki Y. Chung, Alex Tsobanoudis, Daniel James Berg, Antonio Ucar, Reza Nazemzadeh, Thor Johnson, Nainesh Parikh, Brian Kouri, Christopher Laing, Brian A. Boone, Imtiaz Qureshi, Ramtin Agah, Amer H. Zureikat
Publikováno v:
Journal of Clinical Oncology. 41:713-713
713 Background: Locally advanced pancreatic cancer (LAPC) remains one of the deadliest cancers. Radiation is listed as a first line therapy option in treatment guidelines and remains a common treatment for this patient population primarily for local
Autor:
Amer H. Zureikat, Daniel Barnett, Ying Huang, Mirna Kheir Gouda, Luke Wisniewski, Douglas B. Evans, Ben Staal, Chong-Feng Gao, Peter J. Allen, Dennis Plenker, Aatur D. Singhi, Randall E. Brand, Ying Liu, David A. Tuveson, Susan Tsai, Ian Beddows, Mohammed Aldakkak, Brian B. Haab, Johnathan Hall, Richard R. Drake
Publikováno v:
Clin Cancer Res
Purpose:A subset of pancreatic ductal adenocarcinomas (PDACs) is highly resistant to systemic chemotherapy, but no markers are available in clinical settings to identify this subset. We hypothesized that a glycan biomarker for PDACs called sialylated
Autor:
A. Floortje van Oosten, Michael J. Pflüger, Wenjie Huang, Elizabeth D. Thompson, Vincent P. Groot, Steven Gallinger, Sandra Fischer, Limin Xia, Neil M. Neumann, Nicholas J. Roberts, Richard A. Burkhart, Stefan Heinrich, Alina Hasanain, Claudio Luchini, Jin He, Kim-Vy Nguyen-Ngoc, Bernat Navarro-Serer, Anne Macgregor-Das, Laura D. Wood, Maria A. Trujillo, Gemma Lionheart, Andrew J. Ewald, Peter Chianchiano, Michael Goggins, Amer H. Zureikat, Christopher L. Wolfgang, Randall E. Brand, Yea Ji Jeong, Matthias M. Gaida, Cameron Dowiak, Tammy Ng, Aatur D. Singhi, Danielle Jones, Kohei Fujikura, Bo Huang, Nicola Veronese
Publikováno v:
Cancer Res
Pancreatic ductal adenocarcinoma (PDAC) is an aggressive malignancy characterized by extensive local invasion and systemic spread. In this study, we employed a three-dimensional organoid model of human pancreatic cancer to characterize the molecular
Autor:
Jill Krejdovsky, Mary Helen Black, James Ohr, Holly LaDuca, Mary Linton B. Peters, A. James Moser, Arlene Colvin, Nadine Tung, Eve Karloski, Jill S. Dolinsky, Weijing Sun, Virginia Speare, John C. Rhee, Nathan Bahary, Kim DeLeonardis, Melissa E. Hogg, Amer H. Zureikat, Kenneth H. Lee, James Cheng Yen Lee, Randall E. Brand, Beth Dudley, Allan Tsung, Herbert J. Zeh, Lindsey Stobie, Erkut Borazanci, Cynthia Lim, Emily Dalton
Publikováno v:
Cancer. 124:3520-3527
BACKGROUND The objective of this study was to investigate the prevalence of pathogenic germline variants (PGVs) in 32 cancer susceptibility genes in individuals with newly diagnosed pancreatic ductal adenocarcinoma (PDAC). A key secondary objective w
Autor:
You Na Sung, Michele Milella, Herbert J. Zeh, Muaz Aijazi, Jacqueline A. Brosnan-Cashman, Claudio Luchini, Rita T. Lawlor, Alessandro Paniccia, Michael A. Nalesnik, Aatur D. Singhi, Asif Khalid, Roberto Salvia, Koen M.A. Dreijerink, Massimo Milione, Lodewijk A.A. Brosens, G. Johan A. Offerhaus, Nathan Bahary, Melissa E. Hogg, Soyeon An, Marina N. Nikiforova, Ta-Chiang Liu, Samantha Bersani, Harkirat Singh, Savreet Sarkaria, Randall E. Brand, Charlotte M. Heidsma, Wenzel M. Hackeng, Folkert H.M. Morsink, Joo Young Kim, Seung-Mo Hong, Boris Rusev, Adam Slivka, David A. Geller, Kenneth K.W. Lee, Melanie Ongchin, Kenneth E. Fasanella, James F. Pingpank, Sara Cingarlini, Aldo Scarpa, Els J. M. Nieveen van Dijkum, Andrea Mafficini, Rohit Das, Antonio Pea, Menno R. Vriens, Vincenzo Corbo, Luca Landoni, Amer H. Zureikat, Gerlof D. Valk, Roderick J. O’Sullivan, J. Wallis Marsh, Xiaoli Han, Kevin McGrath, Jennifer Chennat, Michelle Heayn, Dengfeng Cao, Christopher M. Heaphy
Publikováno v:
Hackeng, W M, Brosens, L A A, Kim, J Y, O'Sullivan, R, Sung, Y N, Liu, T C, Cao, D, Heayn, M, Brosnan-Cashman, J, An, S, Morsink, F H M, Heidsma, C M, Valk, G D, Vriens, M R, Nieveen Van Dijkum, E, Offerhaus, G J A, Dreijerink, K M A, Zeh, H, Zureikat, A H, Hogg, M, Lee, K, Geller, D, Marsh, J W, Paniccia, A, Ongchin, M, Pingpank, J F, Bahary, N, Aijazi, M, Brand, R, Chennat, J, Das, R, Fasanella, K E, Khalid, A, McGrath, K, Sarkaria, S, Singh, H, Slivka, A, Nalesnik, M, Han, X, Nikiforova, M N, Lawlor, R T, Mafficini, A, Rusev, B, Corbo, V, Luchini, C, Bersani, S, Pea, A, Cingarlini, S, Landoni, L, Salvia, R, Milione, M, Milella, M, Scarpa, A, Hong, S M, Heaphy, C M & Singhi, A D 2021, ' Non-functional pancreatic neuroendocrine tumours : ATRX/DAXX and alternative lengthening of telomeres (ALT) are prognostically independent from ARX/PDX1 expression and tumour size ', Gut . https://doi.org/10.1136/gutjnl-2020-322595
Gut. BMJ Publishing Group
Gut. BMJ Publishing Group
ObjectiveRecent studies have found aristaless-related homeobox gene (ARX)/pancreatic and duodenal homeobox 1 (PDX1), alpha-thalassemia/mental retardation X-linked (ATRX)/death domain-associated protein (DAXX) and alternative lengthening of telomeres
Autor:
Kira L. Russell, Daniel Weber, Nathan Bahary, Pragosh Saini, Aatur D. Singhi, Herbert J. Zeh, Tullia C. Bruno, Viginia Espina, Amer H. Zureikat, Wenjing Pan, Jian Han, Pranav Murthy, Lance A. Liotta, Miranda Byrne-Steele, Michael T. Lotze
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss Suppl 3 (2020)
Background Pancreatic ductal adenocarcinoma (PDAC) is a highly lethal malignancy, characterized by a desmoplastic stromal reaction and an immunosuppressive tumor microenvironment (TME)1. The metabolic stress within the PDAC TME promotes autophagy, a
Autor:
Teng-Kuei Hsu, Christine Decapite, Ofer Shapira, Alessandro Paniccia, Chun Yang, Shivani Mahajan, Richard Bourgon, Peter Ulz, Marvin Bertin, Amit Pasupathy, Julie M. Granka, Adam Drake, C. Jimmy Lin, Tzu-Yu Liu, Preet Kaur, Randall E. Brand, Kaitlyn Coil, Maggie C. Louie, Billie Gould, Hayley Donnella, Amer H. Zureikat, Eric A. Ariazi
Publikováno v:
Cancer Research. 81:PO-007
Pancreatic ductal adenocarcinoma (PDAC) is one of the deadliest cancers, with an overall five-year survival rate of 11%. Potential curative resection is possible if the tumor is detected at an early stage, with a five-year survival rate of 42%. The o