Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Amanda B. Muir"'
Autor:
Mohammad Faujul Kabir, Jazmyne L Jackson, Annie D Fuller, Leonny Gathuka, Adam L Karami, Don-Gerard Conde, Alena Klochkova, Anbin Mu, Kathy Q Cai, Andres J Klein-Szanto, Amanda B Muir, Kelly A Whelan
Publikováno v:
Carcinogenesis. 44:182-195
Esophageal squamous cell carcinoma (ESCC) is one of the most aggressive forms of human malignancy, often displaying limited therapeutic response. Here, we examine the non-steroidal anti-inflammatory drug diclofenac (DCF) as a novel therapeutic agent
Autor:
Manabu Muto, Masataka Shimonosono, Takaaki Arigami, Amanda B. Muir, Masaki Mori, Takashi Kijima, Yuta Kasagi, Shinya Ohashi, Andres J. Klein-Szanto, Prasanna M. Chandramouleeswaran, Narayan G. Avadhani, Itaru Omoto, Shoji Natsugoe, Gregory G. Ginsberg, Seiji Naganuma, Veronique Giroux, Varun Sahu, Yoshiaki Shinden, Osamu Kikuchi, Devraj Basu, J. Alan Diehl, Yasuto Uchikado, Koji Tanaka, Yoshiaki Kita, Yuichiro Doki, Adam J. Bass, Ken Sasaki, Hiroshi Nakagawa, Anil K. Rustgi, Kelly A. Whelan, Takeo Hara
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology, Vol 7, Iss 1, Pp 73-91 (2019)
Cellular and Molecular Gastroenterology and Hepatology, Vol 7, Iss 1, Pp 73-91 (2019)
Background & Aims Oropharyngeal and esophageal squamous cell carcinomas, especially the latter, are a lethal disease, featuring intratumoral cancer cell heterogeneity and therapy resistance. To facilitate cancer therapy in personalized medicine, thre
Autor:
Bailey Aaron, Masataka Shimonosono, Dominique Bailey, Takeo Hara, Julian A. Abrams, Kathryn E. Hamilton, Yuta Kasagi, Veronique Giroux, Hiroshi Nakagawa, Jonathan M. Spergel, Gary W. Falk, Amanda B. Muir, Tatiana A. Karakasheva, Seema S. Aceves, Kelly A. Whelan, Takashi Kijima, Benjamin J. Wilkins
Publikováno v:
Curr Protoc Stem Cell Biol
The homeostatic proliferation-differentiation gradient in the esophageal epithelium is perturbed under inflammatory disease conditions such as gastroesophageal reflux disease and eosinophilic esophagitis. Herein we describe the protocols for rapid ge
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 5, Iss 4, Pp 461-478 (2018)
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology
The stratified squamous epithelium of the esophagus shows a proliferative basal layer of keratinocytes that undergo terminal differentiation in overlying suprabasal layers. Esophageal pathologies, including eosinophilic esophagitis, gastroesophageal
Autor:
Dorottya Laczkó, Divya Rao, Khvaramze Shaverdashvili, Kelly A. Whelan, Amanda B. Muir, Daniel Weinblatt, Wenpeng Jiang, Jennie Padlo, Jonathan P. Katz, Yang Jia, John P. Lynch
Publikováno v:
PLoS ONE, Vol 14, Iss 4, p e0215746 (2019)
Understanding the regulatory mechanisms within esophageal epithelia is essential to gain insight into the pathogenesis of esophageal diseases, which are among the leading causes of morbidity and mortality throughout the world. The zinc-finger transcr
Autor:
Rieko Shimonosono, Bailey Aaron, Takeo Hara, Masataka Shimonosono, Amanda B. Muir, Kristle L. Lynch, Hisatsugu Maekawa, Lauren Dolinsky, Kathryn Nunes, Yuta Kasagi, Hiroshi Nakagawa, Tatiana A. Karakasheva, Joshua Wang, Carmen Rossi
Publikováno v:
Gastroenterology. 158:S-835
Autor:
Reshu Saxena, Mary Grace Murray, Tyler Beccari, Kelly A. Whelan, Julie Gang, Alena Klochkova, Andres J. Klein-Szanto, Amanda B. Muir, Mohammad Faujul Kabir
Publikováno v:
Gastroenterology. 158:S-185
Autor:
Medha Sharma, Veronique Giroux, Alain Benitez, Kathryn E. Hamilton, Anil K. Rustgi, Joshua Wang, Kelly A. Whelan, Andres J. Klein-Szanto, Jonathan M. Spergel, Hiroshi Nakagawa, Gary W. Falk, Prasanna M. Chandramouleeswaran, John W. Tobias, Amanda B. Muir, Koji Tanaka, Maureen DeMarshall, Yuta Kasagi
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology, Vol 5, Iss 3, Pp 333-352 (2018)
Cellular and Molecular Gastroenterology and Hepatology, Vol 5, Iss 3, Pp 333-352 (2018)
Background & Aims Aberrations in the esophageal proliferation-differentiation gradient are histologic hallmarks in eosinophilic esophagitis (EoE) and gastroesophageal reflux disease. A reliable protocol to grow 3-dimensional (3D) esophageal organoids
Autor:
Rebecca G. Wells, Gary W. Falk, Daniel A. Hammer, Kelly A. Whelan, Hiroshi Nakagawa, Dale Lee, Alain Benitez, Steven J. Henry, Maureen DeMarshall, Mei-Lun Wang, Kara K. Dods, Amanda B. Muir, Jonathan M. Spergel
Objectives: Eosinophilic esophagitis (EoE) is an immune-mediated allergic disease characterized by progressive esophageal dysmotility and fibrotic stricture associated with chronic esophageal fibroblast activation. It remains unknown how esophageal f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd643199fb942df0fe4715f2f6d65829
https://europepmc.org/articles/PMC4929044/
https://europepmc.org/articles/PMC4929044/
Autor:
Masumi Wada, Masataka Shimonosono, Prasanna M. Chandramouleeswaran, Amanda B. Muir, Qiaosi Tang, Takashi Kijima, Hiroshi Nakagawa, Yuta Kasagi, Tatiana A. Karakasheva, Anil K. Rustgi, Kelly A. Whelan, Andres J. Klein-Szanto, Shoji Natsugoe
Publikováno v:
Gastroenterology. 156:S-107