Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Alena Klochkova"'
Autor:
Mohammad Faujul Kabir, Jazmyne L Jackson, Annie D Fuller, Leonny Gathuka, Adam L Karami, Don-Gerard Conde, Alena Klochkova, Anbin Mu, Kathy Q Cai, Andres J Klein-Szanto, Amanda B Muir, Kelly A Whelan
Publikováno v:
Carcinogenesis. 44:182-195
Esophageal squamous cell carcinoma (ESCC) is one of the most aggressive forms of human malignancy, often displaying limited therapeutic response. Here, we examine the non-steroidal anti-inflammatory drug diclofenac (DCF) as a novel therapeutic agent
Autor:
Charline Ogier, Alena Klochkova, Linara Gabitova-Cornell, Battuya Bayarmagnai, Diana Restifo, Aizhan Surumbayeva, Debora Barbosa Vendramini-Costa, Ralph Francescone, Janusz Franco-Barraza, Jaye Gardiner, Emmanuelle Nicolas, Andrei Efimov, Elizabeth A. Handorf, Kathy Q. Cai, Bojana Gligorijevic, Edna Cukierman, Igor Astsaturov
Publikováno v:
Cancer Research. 82:C047-C047
Pancreatic ductal adenocarcinoma (PDAC) cells derive their resistance to therapy and aggressive clinical course from the symbiotic signaling and metabolic interactions with cancer-associated fibroblasts (CAFs). Trogocytosis is a process of “nibblin
Autor:
Charline Ogier, Alena Klochkova, Battuya Bayarmagnai, Linara Gabitova, Diana Restifo, Aizhan Surumbayeva, Janusz Franco-Barraza, Debora Vendramini Costa, Ralph Francescone, Jaye Gardiner, Emmanuelle Nicolas, Elizabeth A. Handorf, Kathy Q. Cai, Edna Cukierman, Igor Astsaturov
Publikováno v:
Cancer Research. 82:1571-1571
Pancreatic ductal adenocarcinoma (PDAC) cells derive their resistance to therapy and aggressive clinical course from the symbiotic signaling and metabolic interactions with cancer-associated fibroblasts (CAFs). CAFs have been shown to provide nutrien
Autor:
Charline Ogier, Elizabeth Handorf, Jaye C. Gardiner, Diana Restifo, Ralph Francescone, Janusz Franco-Barraza, Linara Gabitova, Emmanuelle Nicolas, Kathy Q. Cai, Battuya Bayarmagnai, Alena Klochkova, Aizhan Surumbayeva, Igor Astsaturov, Débora Barbosa Vendramini-Costa, Edna Cukierman
Publikováno v:
Cancer Research. 81:PR-015
Pancreatic ductal adenocarcinoma (PDAC) cells derive their resistance to therapy and aggressive clinical course from the symbiotic signaling and metabolic interactions with cancer-associated fibroblasts (CAFs). CAFs have been shown to provide to meta
Autor:
Anbin Mu, Dorian Frazier, Alena Klochkova, Mohammad Faujul Kabir, Adam Karami, Kelly A. Whelan, Andres J. Klein-Szanto
Publikováno v:
Gastroenterology. 160:S-264
Autor:
Adam Karami, Alena Klochkova, Anbin Mu, Brittany Yancey, Mohammad Faujul Kabir, Kelly A. Whelan
Publikováno v:
Gastroenterology. 160:S-660
Autor:
Kelly A. Whelan, Anbin Mu, Alena Klochkova, Adam Karami, Mary Grace Murray, Mohammad Faujul Kabir
Publikováno v:
Gastroenterology. 160:S-661
Cholesterol deprivation induces TGFβ signaling to promote basal differentiation in pancreatic cancer
Autor:
Diana Restifo, Alena Klochkova, Neelima Shah, Ido Sloma, Rachel Chiaverelli, Linara Gabitova, Suraj Peri, Richard A. Moffitt, Emmanuelle Nicolas, Alexandra Mazitova, Kathy Q. Cai, Tiffiney R. Hartman, Edna Cukierman, Erica A. Golemis, Alana M. O’Reilly, Elizabeth Handorf, Igor Astsaturov, Janusz Franco-Barraza, Ralph Francescone
SummaryOncogenic transformation alters the metabolism of cellular nutrients to sustain tumor growth. We here define a mechanism by which modifications in cholesterol metabolism control the formation of pancreatic ductal adenocarcinoma (PDAC). Disrupt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::501275a1cbf2e88f727507f1a817bde7
https://doi.org/10.1101/633719
https://doi.org/10.1101/633719
Autor:
Reshu Saxena, Mary Grace Murray, Tyler Beccari, Kelly A. Whelan, Julie Gang, Alena Klochkova, Andres J. Klein-Szanto, Amanda B. Muir, Mohammad Faujul Kabir
Publikováno v:
Gastroenterology. 158:S-185
Autor:
Edna Cukierman, Diana Restifo, Alena Klochkova, Linara Gabitova, Igor Astsaturov, Tiffiney R. Hartman, Aleksandra M. Mazitova
Publikováno v:
Cancer Research. 77:438-438
Pancreatic cancer is rapidly rising to become the 2nd leading cause of cancer deaths by 2020 in the USA. The rise in pancreatic cancer incidence is paralleled by the epidemic of obesity, type 2 diabetes, and associated increase in blood cholesterol,