Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Marc Valentine"'
Autor:
Stephen P. Hunger, Elizabeth A. Raetz, Julie M. Gastier-Foster, Cheryl L. Willman, Mignon L. Loh, Yu Liu, Brent L. Wood, William L. Carroll, Heather Jenkins, Andrew J. Carroll, Eileen Stonerock, Jonathan V. Nguyen, Michael J. Burke, Yunfeng Dai, Zhaohui Gu, Karen R. Rabin, John Easton, I-Ming Chen, Thai Hoa Tran, Anne L. Angiolillo, Amy Smith, Kathryn G. Roberts, Meenakshi Devidas, Debbie Payne-Turner, Michael J. Borowitz, Marc Valentine, Charles G. Mullighan, Patrick A. Zweidler-McKay, Yongjin Li, Ying Shao, Nyla A. Heerema, Wanda L. Salzer, Jinghui Zhang, Richard C. Harvey, Shalini C. Reshmi
Publikováno v:
Blood. 129(25)
Philadelphia chromosome-like (Ph-like) acute lymphoblastic leukemia (ALL) is a high-risk subtype characterized by genomic alterations that activate cytokine receptor and kinase signaling. We examined the frequency and spectrum of targetable genetic l
Autor:
Yu Liu, Cheryl L. Willman, Meenakshi Devidas, I-Ming Chen, Stephen P. Hunger, Marc Valentine, Brent L. Wood, Shalini C. Reshmi, Mignon L. Loh, Kathryn G. Roberts, Nyla A. Heerema, Wanda L. Salzer, Charles G. Mullighan, Jinghui Zhang, Richard C. Harvey, Andrew J. Carroll, Karen R. Rabin, Michael M. Burke, Anne L. Angiolillo, William L. Carroll, Debbie Payne-Turner, John Easton, Elizabeth A. Raetz, Julie M. Gastier-Foster, Yongjin Li, Ying Shao, Michael J. Borowitz, Amy Smith, Patrick A. Zweidler-McKay
Publikováno v:
Cancer Research. 75:4729-4729
Introduction: While cure rates exceed 80%, many children with B-ALL still relapse. Many of these patients (pts) display a Ph-like gene expression profile (GEP), but lack canonical BCR-ABL1 fusion. We have identified alternate kinase fusions in Ph-lik