Zobrazeno 1 - 10
of 1 323
pro vyhledávání: '"Tamura A"'
Autor:
Tomohide Tamura, Kazumasa Noda, Shinzoh Kudoh, José Baselga, Johan Vansteenkiste, Giuseppe Giaccone, Seiji Yano, Takeshi Horai, Kazuhiko Nakagawa, Ichiro Takata, Rui Ping Dong, Masahiro Fukuoka, Egbert F. Smit, Jean-Yves Douillard, Danny Rischin, Richard Eek, A. Feyereislova, Steven D. Averbuch, Yutaka Nishiwaki, Angela Macleod
Publikováno v:
Journal of Clinical Oncology. 41:1162-1171
PURPOSE To evaluate the efficacy and tolerability of two doses of gefitinib (Iressa [ZD1839]; AstraZeneca, Wilmington, DE), a novel epidermal growth factor receptor tyrosine kinase inhibitor, in patients with pretreated advanced non–small-cell lung
Autor:
Shunsuke Kato, Fumito Yamazaki, Tadashi Kumamoto, Yukiko Tsunematsu, Masatoshi Takagi, Kazuo Tamura, Haruhiko Sugimura, Michinori Funato, Chieko Tamura
Publikováno v:
Cancer Science
Li‐Fraumeni syndrome (LFS) is a hereditary cancer predisposition syndrome, and the majority of patients with LFS have been identified with germline variants in the p53 tumor suppressor (TP53) gene. In the past three decades, considerable case repor
Autor:
Kenji Wakai, Tetsuya Mizoue, Shiori Tanaka, Tetsuhisa Kitamura, Kotaro Ozasa, Shuhei Nomura, Keitaro Matsuo, Shizuka Sasazuki, Michihiro Muto, Hidekazu Suzuki, Taichi Shimazu, Tomio Nakayama, Yingsong Lin, Norie Sawada, Motoki Iwasaki, Tetsuya Otani, Keitaro Tanaka, Isao Oze, Atsuko Sadakane, Shoichiro Tsugane, Sarah Krull Abe, Mariko Naito, Eiko Saito, Yoshikazu Nishino, Yoshitaka Tsubono, Chisato Nagata, Yumi Sugawara, Keiko Wada, Ayami Ono, Taiki Yamaji, Takashi Tamura, Ichiro Tsuji, Hidemi Ito, Yuri Kitamura, Hadrien Charvat, Akiko Tamakoshi, Mai Utada, Mamami Inoue
Publikováno v:
Cancer Science
The association between alcohol intake and stomach cancer risk remains controversial. We undertook a pooled analysis of data from six large‐scale Japanese cohort studies with 256 478 participants on this topic. Alcohol intake as ethanol was estimat
Autor:
Takahiko Nakamura, Kenjiro Tsuruoka, Kiyoe Kanaoka, Yosuke Tamura, Yasuhito Fujisaka, Soichiro Ikeda, Tomoya Funamoto, Masafumi Imanishi, Isao Goto, Akihisa Imagawa, Hiroyuki Tsuji, Sho Mitsuya, Ninso Matsunaga
Publikováno v:
Anticancer Research. 41:5137-5145
BACKGROUND For epidermal growth factor receptor (EGFR)-mutated non-small cell lung cancer (NSCLC), administration of EGFR tyrosine kinase inhibitors (TKIs) is mandatory to prolong survival. To date, a comparison of second- and third-generation EGFR-T
Autor:
Yen-Shen Lu, Winnie Yeo, Yeon Hee Park, Yoon Sim Yap, Rebecca Cheng, Huiping Li, Kenji Tamura
Publikováno v:
Targeted Oncology
Breast cancer (BC) among Asians accounts for ~ 40% of the global BC burden. Differences in BC risk, presentation, tumor biology, and response to treatment exist between Asian and non-Asian patients; however, Asian patients are often under-represented
Autor:
Li Yuan Bai, Yee Chao, Narikazu Boku, Taroh Satoh, Hyun Cheol Chung, Masahiro Tsuda, Won Ki Kang, Yoon-Koo Kang, Jae Yong Cho, Jen-Shi Chen, Ken Kato, Jong Gwang Kim, Yasuo Hamamoto, Keiko Minashi, Keun Wook Lee, Kun-Huei Yeh, Hiroki Sameshima, Keisho Chin, Sang Cheul Oh, Li-Tzong Chen, Kei Muro, Takaki Yoshikawa, Min Hee Ryu, Takao Tamura, Do Youn Oh, Satoshi Morita
Publikováno v:
Gastric Cancer
Background The phase 3 ATTRACTION-2 study demonstrated that nivolumab monotherapy was superior to placebo for patients with pretreated advanced gastric or gastroesophageal junction cancer, but early progression of tumors in some patients was of conce
Publikováno v:
Anticancer Research. 41:4013-4016
Background Low-grade endometrial stromal sarcoma (LG-ESS) is an indolent tumor harboring gene fusion involving polycomb family genes. While early LG-ESS has a good clinical course, some tumors have pelvic recurrence. The etiology and genetic alterati
Autor:
Kuniko Sunami, Tetsu Hayashida, Kazuto Nishio, Shinji Kohsaka, Ichiro Kinoshita, Hiroyuki Uetake, Kenji Tamura, Koshi Mimori, Hideaki Takahashi, Shinichi Toyooka, Noboru Yamamoto, Hideaki Bando, Masayuki Takeda, Keigo Komine, Katsuya Tsuchihara, Yoichi Naito, Yasushi Yatabe
Publikováno v:
Cancer Science
Comprehensive genomic profiling (CGP) is being increasingly used for the routine clinical management of solid cancers. In July 2018, the use of tumor tissue‐based CGP assays became available for all solid cancers under the universal health insuranc
Autor:
Yuta Sekino, Taro Shibata, Hiroji Iwata, Tomonori Mizutani, Akihiko Shimomura, Masataka Sawaki, Tadahiko Shien, Keita Sasaki, Kiyo Tanaka, Kenji Tamura
Publikováno v:
Japanese Journal of Clinical Oncology. 51:1471-1474
The standard first-line treatment for patients with human epidermal growth factor 2-positive metastatic breast cancer is a combination therapy of trastuzumab, pertuzumab and docetaxel, and the standard second-line treatment is trastuzumab emtansine.
Autor:
Kan Yonemori, Nobuko Tamura, Kenji Tamura, Mayu Yunokawa, Yasuhiro Fujiwara, Yuko Tanabe, Junko Hasegawa, Kenji Hashimoto, Kazutaka Ikeda, Toshimi Takano, Daisuke Nishizawa, Akihiko Shimomura, Chikako Shimizu, Seiji Shiraishi, Yukinori Ozaki, Hidetaka Kawabata
Publikováno v:
BMC Cancer, Vol 20, Iss 1, Pp 1-7 (2020)
BMC Cancer
BMC Cancer
Background Sodium channels located in the dorsal root ganglion, particularly Nav1.7 and Nav1.8, encoded by SCN9A and SCN10A, respectively, act as molecular gatekeepers for pain detection. Our aim was to determine the association between TIPN and SCN9