Zobrazeno 1 - 10
of 135 144
pro vyhledávání: '"medicine"'
Publikováno v:
Cancer Biotherapy and Radiopharmaceuticals. 38:122-131
Background: Gastric cancer (GC) is a common tumor found worldwide, and cisplatin is the first-line agent for the treatment of GC. However, the resistance to cisplatin is an obstacle. Here, we aim to explore the biological mechanism of long noncoding
Publikováno v:
Genes & Diseases. 10:415-429
Long non-coding RNAs (lncRNAs) are a novel class of non-coding RNA (ncRNA), that have been studied extensively in the field of tumor research in recent years. In the case of tumor-associated lncRNAs, lncRNA cytoskeleton regulator RNA (CYTOR) displays
Publikováno v:
Genes & Diseases. 10:403-414
KRAS is one of the most commonly mutated oncogenes in cancers and therapeutics directly targeting the KRas have been challenging. Among the different known mutants, KRasG12C has been proved to be successfully targeted recently. Several covalent inhib
Autor:
Sheetal Kashyap, Sasanka Chakrabarti, Adesh K. Saini, Neeraj K. Saini, Vipin Saini, Gourav Chandan, Vijay Kumar Thakur, Amit Mittal, Reena V. Saini, Soumya Pal
Publikováno v:
Seminars in Cancer Biology. 86:643-651
The interaction between gut microbes and gastrointestinal (GI) tract carcinogenesis has always attracted researchers' attention to identify therapeutic targets or potential prognostic biomarkers. Various studies have suggested that the microbiota do
Autor:
Sabia Rashid, Atul Chikara, Alexandre Gomes Rodrigues, Sandeep Sisodiya, Sheeraz Un Nazir, Shazia Rashid, Pranay Tanwar, Ajit Kumar Passari, Asiya Khan, Umme Abiha, Showket Hussain, Ankan Mukherjee Das, Bhudev C. Das
Publikováno v:
Seminars in Cancer Biology. 86:583-589
The persistent infection of high-risk Human papillomavirus (HR-HPV) induced cervical cancer remains a challenge in women worldwide including India. Recent advances in cancer research have paved the way for advanced cancer treatment modalities includi
Autor:
Hang Fai Kwok, Muhammad Jameel Mughal
Publikováno v:
Seminars in Cancer Biology. 86:1026-1044
The active role of bacteria in oncogenesis has long been a topic of debate. Although, it was speculated to be a transmissible cause of cancer as early as the 16th-century, yet the idea about the direct involvement of bacteria in cancer development ha
Publikováno v:
Seminars in Cancer Biology. 86:26-35
The chaperonins CCT and Hsp60 are molecular chaperones, members of the chaperone system (CS). Chaperones are cytoprotective but if abnormal in quantity or quality they may cause diseases, the chaperonopathies. Here, recent advances in the understandi
Publikováno v:
Cancer Biotherapy and Radiopharmaceuticals. 37:850-861
Background: Epithelial splicing regulatory proteins (ESRPs) can regulate alternative splicing of RNA and play roles in tumorigenesis and development of various malignancies. In this study, bioinfor...
Autor:
Bo La Yun, Eunyoung Kang, Hee-Chul Shin, Sun Mi Kim, Eun Kyu Kim, Se Hyun Kim, Mijung Jang, Jee Hyun Kim, So Yeon Park, Yeshong Park, Kyung-Hwak Yoon, Koung Jin Suh
Publikováno v:
Cancer Research and Treatment. 54:1081-1090
PurposeEstrogen receptor (ER) expression in breast cancer plays an essential role in carcinogenesis and disease progression. Recently, tumors with low level (1-10%) of ER expression have been separately defined as ER Low Positive (ERlow). It is sugge
Publikováno v:
Cancer Biotherapy and Radiopharmaceuticals. 37:708-719
Background: Circular RNAs (circRNAs) have important roles in human malignancies, including breast cancer (BC). In this study, we intended to explore the function of circRNA ribonuclease P RNA component H1 (circ_RPPH1) in BC development and clarify th