Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Wenyu Lin"'
Autor:
Nadia Alatrakchi, Tuo Shao, Myung-Ho Kim, Wenyu Lin, Shadi Salloum, Raymond T. Chung, Annie J. Kruger, Andre J Jeyarajan, Kathleen E. Corey, Stuti Shroff, Andrew Kassa, Zhu Zhuo, Sanjoy K. Khan, Mozhdeh Sojoodi, Jacinta A Holmes, Esperance A. Schaefer
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 12, Iss 4, Pp 1297-1310 (2021)
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology
Background & Aims Patients with simple steatosis (SS) and nonalcoholic steatohepatitis can develop progressive liver fibrosis, which is associated with liver-related mortality. The mechanisms contributing to liver fibrosis development in SS, however,
Autor:
Yingying Su, Yafang Kang, Diling Pan, Pengming Sun, Lihua Chen, Binhua Dong, Wenyu Lin, Huifeng Xue, Guanyu Ruan, Xiaodan Mao
Publikováno v:
Cancer Cell International, Vol 20, Iss 1, Pp 1-14 (2020)
Cancer Cell International
Cancer Cell International
BackgroundNew screening techniques may affect the optimal approaches for the prevention of cervical cancer. We evaluated the cost-effectiveness and accuracy of alternative screening strategies to provide evidence for cervical cancer screening guideli
Autor:
Chen Qu, Hao Wang, Shuang Peng, Xue Ning, Jian Hong, Aimin Li, Wenyu Lin, Yue Luo, Peng Chen, Xiaojun Luo, Penghui Xie, Guanqi Dai, Yuchuan Jiang
Publikováno v:
Experimental & Molecular Medicine
Experimental and Molecular Medicine, Vol 52, Iss 7, Pp 1062-1074 (2020)
Experimental and Molecular Medicine, Vol 52, Iss 7, Pp 1062-1074 (2020)
Dexmedetomidine (DEX) is an anesthetic that is widely used in the clinic, and it has been reported to exhibit paradoxical effects in the progression of multiple solid tumors. In this study, we sought to explore the mechanism by which DEX regulates he
Autor:
Binhua Dong, Pengming Sun, Yafang Kang, Qiaoyu Zhang, Xiaodan Mao, Wenyu Lin, Lihua Chen, Guanyu Ruan
Publikováno v:
Medical Oncology. 37
The relationship between high-risk-human-papillomavirus (HR-HPV) viral loads and residual/recurrence lesion is uncertain. This study aimed to evaluate the clinical value of HR-HPV viral loads to predict the residual/recurrence lesions among women wit
Autor:
Yuchuan Jiang, Jinying Li, Chen Qu, Wenyu Lin, Guanqi Dai, Jian Hong, Shuang Peng, Hui Yuan, Penghui Xie, Lu He, Raymond T. Chung, Kaishun Hu, Dandan Zheng, Mengxian Tu, Peng Chen
Publikováno v:
Journal of Cellular and Molecular Medicine
The pro‐inflammatory and pro‐fibrotic liver microenvironment facilitates hepatocarcinogenesis. However, the effects and mechanisms by which the hepatic fibroinflammatory microenvironment modulates intrahepatic hepatocellular carcinoma (HCC) progr
Autor:
Yuwen Li, Wang Kun, Chuanlong Zhu, Tiantian Zhu, Wenyu Lin, Jun Li, Yongting Zhang, Wenting Li
Publikováno v:
Stem Cell Research & Therapy, Vol 8, Iss 1, Pp 1-10 (2017)
Stem Cell Research & Therapy
Stem Cell Research & Therapy
Background Transplantation of bone marrow-derived mesenchymal stem cells (BMSCs) has emerged as a novel therapy for acute liver failure (ALF). However, the homing efficiency of BMSCs to the injured liver sites appears to be poor. In this study, we ai
Autor:
Jay Luther, Martin L. Yarmush, Nadia Alatrakchi, Shadi Salloum, Raymond T. Chung, Annie J. Kruger, Anna Lidofsky, Rohit Jindal, Shyam Sundhar Bale, Cynthia Brisac, Dahlene N. Fusco, Wenyu Lin, Esperance A. Schaefer, Jacinta A. Holmes
Publikováno v:
Hepatology. 64:1951-1968
HIV/HCV co-infection accelerates progressive liver fibrosis, however the mechanisms remain poorly understood. HCV and HIV independently induce profibrogenic markers TGFβ1 (mediated by reactive oxygen species (ROS)) and NFκB in hepatocytes and hepat
Autor:
Jacinta A. Holmes, Yuchuan Jiang, Wenyu Lin, Dandan Zheng, Mengxian Tu, Yadi Liao, Weiming Li, Hui Yuan, Bryan C. Fuchs, Xijun Chen, Jian Hong, Lu He, Qimeng Jin, Yingjun Liu, Sai Li, Qiaoting Hu, Zelong Lin, Raymond T. Chung, Lan Wei, Jianning Chen, Anna Lidofsky, Chen Qu
Publikováno v:
Hepatology (Baltimore, Md.). 68(3)
Spleen tyrosine kinase (SYK) plays a critical role in immune cell signaling pathways and has been reported as a biomarker for human hepatocellular carcinoma (HCC). We sought to investigate the mechanism by which SYK promotes liver fibrosis and to eva
Autor:
Wenyu Lin, Chuanlong Zhu, Yi Liang, Binkui Li, Jian Hong, Yadi Liao, Raymond T. Chung, Jia Le Dai, Zongwei Wang, Yi Xin Zeng, Jianping Wang, Ruhai Zou, Pinzhu Huang, Yunfei Yuan
The spleen tyrosine kinase (SYK) has been reported as a novel biomarker for human hepatocellular carcinoma, but the functional contributions of its two isoforms SYK(L) and SYK(S) are undefined. In this study, we investigated their biologic functions
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70587b5dd44bbbdebdabb7c1b44490cc
https://europepmc.org/articles/PMC3959256/
https://europepmc.org/articles/PMC3959256/
Autor:
Wenyu Lin, Eun Kyung Cho, Young Seok Kim, Jae Young Jang, Eui Ju Park, Hong Soo Kim, Woong Cheul Lee, Sang Gyune Kim, Soung Won Jeong, Sae Hwan Lee, Boo Sung Kim, Seong-Jun Kim, Raymond T. Chung
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e98171 (2014)
PLoS ONE
PLoS ONE
Hepatitis C virus (HCV) infection causes chronic liver diseases leading to hepatocellular carcinoma (HCC) and liver failure. We have previously shown that HCV sensitizes hepatocytes to mitochondrial apoptosis via the TRAIL death receptors DR4 and DR5