Zobrazeno 1 - 4
of 4
pro vyhledávání: '"M, Aydin"'
Autor:
James J. Mulé, Esther Katende, Michelle Fournier, Jad Chahoud, Dongliang Du, Jamie K. Teer, Young-Chul Kim, Neale Lopez-Blanco, Anders Berglund, Chia-Ho Cheng, Jasreman Dhillon, Ahmet M. Aydin, Logan Zemp, Philippe E. Spiess, Liang Wang, Carlos Moran-Segura, Wenyi Fan, Jonathan Nguyen, Sean J. Yoder, Brandon J. Manley, Nicholas H. Chakiryan, Ali Hajiran
Publikováno v:
European urology focus. 8(3)
Background Clear cell renal cell carcinoma (ccRCC) tumors have low frequencies of genetic alterations compared with other malignancies, but very high levels of immune cell infiltration and favorable response rates to immunotherapy. Currently, the int
Autor:
Asmaa El-Kenawi, Gregory J. Kimmel, Carlos Moran-Segura, Jasreman Dhillon, Jad Chahoud, James J. Mule, Logan Zemp, Philippe E. Spiess, Neale Lopez-Blanco, Philipp M. Altrock, Esther Katende, Jonathan Nguyen, Michelle Fournier, Liang Wang, Brandon J. Manley, Ahmet M. Aydin, Nicholas H. Chakiryan, Ali Hajiran, Youngchul Kim
Publikováno v:
PLoS ONE, Vol 16, Iss 4, p e0245415 (2021)
PLoS ONE
PLoS ONE
Immune infiltration is typically quantified using cellular density, not accounting for cellular clustering. Tumor-associated macrophages (TAM) activate oncogenic signaling through paracrine interactions with tumor cells, which may be better reflected
Autor:
Philippe E. Spiess, Carlos Moran-Segura, Ali Hajiran, John M. Koomen, Jose Laborde, Jonathan Nguyen, Nick Chakiryan, Wade J. Sexton, Young-Chul Kim, Jad Chahoud, Logan Zemp, Brandon J. Manley, Saif Zaman, Esther Katende, Michelle Fournier, Shayan Falasiri, Jamie K. Teer, Jasreman Dhillon, Ahmet M. Aydin, Susan McCarthy, James J. Mulé
Publikováno v:
Clin Exp Immunol
Summary A clearer understanding of the tumor immune microenvironment (TIME) in metastatic clear cell renal cell carcinoma (ccRCC) may help to inform precision treatment strategies. We sought to identify clinically meaningful TIME signatures in ccRCC.
Autor:
Sarah Asby, Brittany L. Bunch, Jamie Blauvelt, Michael A. Poch, Matthew Beatty, Ali Hajiran, Shari Pilon-Thomas, Ahmet M. Aydin, Jennifer Morse, Patrick Innamarato
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 2 (2020)
Journal for Immunotherapy of Cancer
Journal for Immunotherapy of Cancer
BackgroundThe therapeutic armamentarium of bladder cancer has been recently enriched with the introduction of new therapies including immune checkpoint inhibitors, receptor tyrosine kinase inhibitors and antibody drug conjugates, however treatment re