Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Perrotti A"'
Autor:
Marta Acchioni, Anna Lisa Remoli, Angela Battistini, Robert Clarke, Chiara Acchioni, Giulia Marsili, Roberto Orsatti, Edvige Perrotti, Marco Sgarbanti
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 22, Iss 10, Pp 459-469 (2020)
Neoplasia (New York, N.Y.)
Neoplasia (New York, N.Y.)
Interferon Regulatory Factors (IRFs) are key regulators of immunity, cell survival and apoptosis. IRF transcriptional activity and subcellular localization are tightly regulated by posttranscriptional modifications including phosphorylation. The IκB
Autor:
Antonella Colasante, Monica Di Tommaso, Giulia Sindici, F. Perrotti, Antonietta Augurio, Giuseppe Pizzicannella, Domenico Angelucci, Pierluigi Di Sebastiano, Nicola Di Bartolomeo, Marta Di Nicola, Massimo Basti, V. Borzillo, Paolo Innocenti, Maria Taraborrelli, Luciana Caravatta, Michele Marchioni, Consuelo Rosa, Domenico Genovesi, Roberta Cianci, Sara Di Santo, Lorenzo Mazzola
Publikováno v:
In Vivo
Aim Pathological complete response (pCR) and clinical outcomes [overall survival (OS), disease-free survival (DFS), locoregional control (LC)] were evaluated in a single-institution experience of different schedules of neoadjuvant chemoradiotherapy (
Autor:
Nicola Perrotti, Silvia Schenone, Stefano Marianelli, Annarita Cianciusi, Claudia Immacolata Trivisani, Arianna Mancini, Lucia D'Antona, Annalaura Brai, Alessio Molinari, Elena Dreassi, Claudio Zamperini, Enrico Rango, Anna Lucia Fallacara, Maurizio Botta, Giulia Iovenitti
Publikováno v:
European journal of medicinal chemistry. 223
Si113, a pyrazolo[3,4-d]pyrimidine derivative, gained more attention as an anticancer agent due to its potent anticancer activity on both in vitro and in vivo hepatocellular carcinomas (HCC) and ovarian carcinoma models. But the drawback is the low w
Autor:
Giovannino Silvestri, Pavel Burda, Pavla Pecherkova, Rossana Trotta, Klara Srutova, Filipp Savvulidi, Zofie Sovova, Hana Klamova, Tomas Stopka, Katerina Machova Polakova, Danilo Perrotti, Jitka Koblihova, Nikola Curik
Publikováno v:
Haematologica
The fusion oncoprotein BCR-ABL1 exhibits aberrant tyrosine kinase activity and it has been proposed that it deregulates signaling networks involving both transcription factors and non-coding microRNAs that result in chronic myeloid leukemia (CML). Pr
Autor:
Clelia Di Carlo, Carmen Cefalogli, Marianna Nuzzo, Luciana Caravatta, F. Perrotti, Marianna Trignani, Ambra Pamio, Lucia Anna Ursini, Domenico Genovesi, Marta Di Nicola
Publikováno v:
In Vivo. 31:151-158
Aim To evaluate locoregional recurrence, overall survival, disease-free survival and prognostic influence of the number of positive lymph nodes and other variables in breast cancer treatment. Patients and methods A total of 377 patients with pT1-T2,
Autor:
Tej K. Pandita, Linda I. Perrotti, Samara A.M. Bobzean, Khairul I. Ansari, Arunoday Bhan, Paromita Deb, Imran Hussain, Subhrangsu S. Mandal
Publikováno v:
Gene. 590:234-243
HOXB9 is a homeobox-containing gene that plays a key role in mammary gland development and is associated with breast and other types of cancer. Here, we demonstrate that HOXB9 expression is transcriptionally regulated by estradiol (E2), in vitro and
Autor:
Jamshid S. Khorashad, Mary Alikian, Edward Curry, Sandra Loaiza, Gareth Gerrard, Danilo Perrotti, Zacharoula Nikolakopoulou, Georgios Nteliopoulos, Jane F. Apperley, Dragana Milojkovic, Simone Claudiani, Alexandra Bazeos, Robert Peter Gale, Richard Szydlo, Hui En Foong, Letizia Foroni
Publikováno v:
Haematologica
There are no validated molecular biomarkers to identify newly-diagnosed individuals with chronic-phase chronic myeloid leukemia likely to respond poorly to imatinib and who might benefit from first-line treatment with a more potent second-generation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35111f1f66d02e33b90cd541053a7a4e
http://hdl.handle.net/10044/1/70475
http://hdl.handle.net/10044/1/70475
Autor:
Justine V. Cohen, Thuy Tran, Elizabeth Perrotti, Christopher R. Zito, Mario Sznol, James B. Yu, Sarah B. Goldberg, Veronica Chiang, Yuval Kluger, Upendra P. Hegde, Lucia B. Jilaveanu, RN Amanda Ralabate, Harriet M. Kluger, Wei Wei, Amit Mahajan, Sarah A. Weiss, Gail Anderson
Publikováno v:
Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 37(1)
Purpose Pembrolizumab is active in melanoma, but activity in patients with untreated brain metastasis is less established. We present long-term follow-up of pembrolizumab-treated patients with new or progressing brain metastases treated on a phase II
Autor:
Silvia Schenone, Paola Mirra, Luca Ulianich, Gaetano Calì, Teresa Tortora, Francesca Fiory, Francesco Beguinot, Rosario Amato, Domenico Conza, Luigi Insabato, Nicola Perrotti
Publikováno v:
Journal of cellular physiology
(2017). doi:10.1002/jcp.25850
info:cnr-pdr/source/autori:Conza, Domenico; Mirra, Paola; Cali, Gaetano; Tortora, Teresa; Insabato, Luigi; Fiory, Francesca; Schenone, Silvia; Amato, Rosario; Beguinot, Francesco; Perrotti, Nicola; Ulianich, Luca/titolo:The SGK1 inhibitor SI113 induces autophagy, apoptosis, and endoplasmic reticulum stress in endometrial cancer cells./doi:10.1002%2Fjcp.25850/rivista:Journal of cellular physiology (Print)/anno:2017/pagina_da:/pagina_a:/intervallo_pagine:/volume
(2017). doi:10.1002/jcp.25850
info:cnr-pdr/source/autori:Conza, Domenico; Mirra, Paola; Cali, Gaetano; Tortora, Teresa; Insabato, Luigi; Fiory, Francesca; Schenone, Silvia; Amato, Rosario; Beguinot, Francesco; Perrotti, Nicola; Ulianich, Luca/titolo:The SGK1 inhibitor SI113 induces autophagy, apoptosis, and endoplasmic reticulum stress in endometrial cancer cells./doi:10.1002%2Fjcp.25850/rivista:Journal of cellular physiology (Print)/anno:2017/pagina_da:/pagina_a:/intervallo_pagine:/volume
Endometrial cancer is often characterized by PI3K/AKT pathway deregulation. Recently it has been suggested that SGK1, a serine/threonine protein kinase that shares structural and functional similarities with the AKT family, might play a role in cance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b40139422ccd42e7168d3261bfb16a3e
http://hdl.handle.net/11588/671893
http://hdl.handle.net/11588/671893
Autor:
Alison Walker, Jihane Khalife, Yan Jin, Sebastian Schwind, Malori A. Lankenau, Bo Yu, Xiaomeng Huang, Pia Hoellerbauer, Hongyan Wang, Ramasamy Santhanam, Chi-Ling Chiang, Danilo Perrotti, Somayeh S. Tarighat, Ann-Kathrin Eisfeld, Guido Marcucci, Ly James Lee, Clara D. Bloomfield, Robert J. Lee
Publikováno v:
Oncotarget
// Xiaomeng Huang 1, 2, 3, * , Sebastian Schwind 3, * , Ramasamy Santhanam 3 , Ann-Kathrin Eisfeld 3 , Chi-ling Chiang 2, 3 , Malori Lankenau 3 , Bo Yu 2, 4 , Pia Hoellerbauer 3 , Yan Jin 2 , Somayeh S. Tarighat 1, 3 , Jihane Khalife 1, 3 , Alison Wa