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Autor:
Bárbara Costa, Nuno Vale
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 7, p 6050 (2023)
The anti-epileptic drug lamotrigine (LTG) has been widely used to treat various neurological disorders, including epilepsy and bipolar disorder. However, its precise mechanism of action in the central nervous system (CNS) still needs to be determined
Externí odkaz:
https://doaj.org/article/2d07985a08ca41ee9a2cbc16de3aa999
Publikováno v:
AIDS Weekly; 5/13/2024, p33-33, 1p
Publikováno v:
Cancer Weekly; 5/9/2024, p630-630, 1p
Publikováno v:
J Biomol Struct Dyn
Modulation of proteasome function by pharmacological interventions and molecular biology tools is an active area of research in cancer biology and neurodegenerative diseases. Curcumin (diferuloylmethane) is a naturally occurring polyphenol that affec
Autor:
Lorinda Simms, Shehkar Patil, David R. Gandara, Anders Mellemgaard, Raghunadharao Digumarti, Bonne Biesma, Johan Vansteenkiste, Mauro Zukin, Joachim von Pawel, Katherine P. Sugarman, Keunchil Park, Christian Manegold, Filippo de Marinis, Tuncay Göksel, Janusz Rolski, Piotr Serwatowski, Jin S. Lee, Giorgio V. Scagliotti, Ulrich Gatzemeier, Purvish M. Parikh
Publikováno v:
Journal of Clinical Oncology. 41:2458-2466
PURPOSE Cisplatin plus gemcitabine is a standard regimen for first-line treatment of advanced non–small-cell lung cancer (NSCLC). Phase II studies of pemetrexed plus platinum compounds have also shown activity in this setting. PATIENTS AND METHODS
Autor:
David H. Johnson, Roy S. Herbst, Corey J. Langer, Louis Fehrenbacher, William Novotny, Eric Holmgren, Jacques Gaudreault, John Nemunaitis, David M. Jablons, Fairooz F. Kabbinavar, Russell F. DeVore, Lisa A. Damico
Publikováno v:
Journal of Clinical Oncology. 41:2305-2312
Purpose To investigate the efficacy and safety of bevacizumab plus carboplatin and paclitaxel in patients with advanced or recurrent non-small-cell lung cancer. Patients and Methods In a phase II trial, 99 patients were randomly assigned to bevacizum
Autor:
Thayer, Kelly M.1,2 kthayer@wesleyan.edu, Beyer, George A.3
Publikováno v:
PLoS ONE. 3/18/2016, Vol. 11 Issue 3, p1-13. 13p.
Publikováno v:
PLoS ONE. 2/10/2016, Vol. 11 Issue 2, p1-14. 14p.
Publikováno v:
Drug Week; 4/12/2024, p806-806, 1p