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Autor:
Thayer, Kelly M.1,2 kthayer@wesleyan.edu, Beyer, George A.3
Publikováno v:
PLoS ONE. 3/18/2016, Vol. 11 Issue 3, p1-13. 13p.
Publikováno v:
Cancer Biotherapy and Radiopharmaceuticals. 38:122-131
Background: Gastric cancer (GC) is a common tumor found worldwide, and cisplatin is the first-line agent for the treatment of GC. However, the resistance to cisplatin is an obstacle. Here, we aim to explore the biological mechanism of long noncoding
Publikováno v:
J Biomol Struct Dyn
Modulation of proteasome function by pharmacological interventions and molecular biology tools is an active area of research in cancer biology and neurodegenerative diseases. Curcumin (diferuloylmethane) is a naturally occurring polyphenol that affec
Publikováno v:
Cannabis and cannabinoid research. 7(5)
Background: Endogenous and synthetic cannabinoids have been shown to induce cancer cell death through the accumulation of the sphingolipid, ceramide (Cer). Recently, we have demonstrated that Cer accumulation enhances the induction of immunogenic cel
Publikováno v:
Cancer Biotherapy and Radiopharmaceuticals. 37:976-986
Colorectal cancer (CRC) is one of the most common cancers worldwide. In this study, we explored the role of RNA binding motif protein 15 (RBM15)-mediated MyD88 mRNA N6-methyladenosine (m6A) in CRC development. Cell proliferation, apoptosis, and invas
Publikováno v:
Cancer Biotherapy and Radiopharmaceuticals. 37:871-881
Background: Colorectal cancer (CRC) is the third most common malignancy worldwide. Matrine can act as a potential antitumor drug, and its antitumor activities have been tested in various cancers, including CRC. However, the effect of matrine and the
Publikováno v:
Anti-Cancer Agents in Medicinal Chemistry. 22:3239-3268
Heterocyclic compounds offer an enormous area for new lead molecules for drug discovery. Till today, efforts are being continuously made to find appropriate treatment for the management of the deadly disease of cancer. Amongst the large number of het
Discovery, Development and Design of Anthocyanins-Inspired Anticancer Agents: A Comprehensive Review
Autor:
Sasadhar Majhi
Publikováno v:
Anti-Cancer Agents in Medicinal Chemistry. 22:3219-3238
Mother Nature is an indispensable source of bioactive natural products. Bioactive secondary metabolites have played a crucial role in the drug development and discovery process; mainly, anticancer and antibiotic molecules are extensively enriched wit
Autor:
Zahra Avan, Seyed Mohammad Abedi, Seyed Jalal Hosseinimehr, Javad Biabani Ardakani, Fereshteh Talebpour Amiri
Publikováno v:
Cancer Biotherapy and Radiopharmaceuticals. 37:862-869
Purpose: The assessment of HER2 expression has a significant impact on optimizing cancer treatment protocol in patients. The aim of this study was to evaluate the potential usefulness of 99mTc-HYNIC-(Ser)3-LTVPWY peptide for detecting HER2 alteration
Autor:
Xiaofeng Xu, Hua Han
Publikováno v:
Cancer Biotherapy and Radiopharmaceuticals. 37:779-791
Background: Both microRNA (miR)-205 and GATA Binding Protein 3 (GATA3) were involved in cervical cancer (CC), yet their correlation remained poorly understood. The authors' study aimed to unveil their correlation in CC. Materials and Methods: Clinica