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Publikováno v:
Cancer Biotherapy and Radiopharmaceuticals. 38:122-131
Background: Gastric cancer (GC) is a common tumor found worldwide, and cisplatin is the first-line agent for the treatment of GC. However, the resistance to cisplatin is an obstacle. Here, we aim to explore the biological mechanism of long noncoding
Publikováno v:
Current Molecular Medicine. 23:177-184
Aims: This study aimed to evaluate the roles and molecular targets of miRNA-141-3p in the cisplatin sensitivity of osteosarcoma. Background: Osteosarcoma is one of the most common-type bone tumors, occurring mainly in children and adolescents. Cancer
Publikováno v:
Cancer Biotherapy and Radiopharmaceuticals. 37:976-986
Colorectal cancer (CRC) is one of the most common cancers worldwide. In this study, we explored the role of RNA binding motif protein 15 (RBM15)-mediated MyD88 mRNA N6-methyladenosine (m6A) in CRC development. Cell proliferation, apoptosis, and invas
Publikováno v:
Cancer Biotherapy and Radiopharmaceuticals. 37:871-881
Background: Colorectal cancer (CRC) is the third most common malignancy worldwide. Matrine can act as a potential antitumor drug, and its antitumor activities have been tested in various cancers, including CRC. However, the effect of matrine and the
Autor:
Zahra Avan, Seyed Mohammad Abedi, Seyed Jalal Hosseinimehr, Javad Biabani Ardakani, Fereshteh Talebpour Amiri
Publikováno v:
Cancer Biotherapy and Radiopharmaceuticals. 37:862-869
Purpose: The assessment of HER2 expression has a significant impact on optimizing cancer treatment protocol in patients. The aim of this study was to evaluate the potential usefulness of 99mTc-HYNIC-(Ser)3-LTVPWY peptide for detecting HER2 alteration
Publikováno v:
Cancer Biotherapy and Radiopharmaceuticals. 37:708-719
Background: Circular RNAs (circRNAs) have important roles in human malignancies, including breast cancer (BC). In this study, we intended to explore the function of circRNA ribonuclease P RNA component H1 (circ_RPPH1) in BC development and clarify th
Autor:
Kiriazis, Alexandros1,2, Vahakoski, Riitta L.3,4, Santio, Niina M.3,4, Arnaudova, Ralica1,3, Eerola, Sini K.3, Rainio, Eeva-Marja3, Aumüller, Ingo B.1, Yli-Kauhaluoma, Jari1 jari.yli-kauhaluoma@helsinki.fi, Koskinen, Päivi J.3 paivi.koskinen@utu.fi
Publikováno v:
PLoS ONE. Feb2013, Vol. 8 Issue 2, p1-13. 13p.
Publikováno v:
Cutaneous and Ocular Toxicology. 41:203-209
PURPOSE As a characteristic of age-related macular degeneration (AMD), choroidal neovascularization (CNV) causes severe vision loss. The current treatment has limited efficacy. This study was to investigate effects of Salidroside against CNV and expl
Autor:
Jianmin Chen, Songying Zhang, Dong Huang, Liaobing Xin, Cheng Wei, Lie Ma, Xiaomei Tong, Yangyang Dai
Publikováno v:
Bioactive Materials, Vol 12, Iss, Pp 107-119 (2022)
Bioactive Materials
Bioactive Materials
Stem cell-based and stem cell-derived exosome-based therapies have shown promising potential for endometrial regeneration and the clinical treatment of intrauterine adhesions (IUAs). Evidence shows that apoptosis occurs in a majority of grafted stem
Autor:
Maftuna Shamshiddinova, Jitendra Shrestha, Yong-Moon Lee, Dong Jae Baek, Yoon Sin Oh, Eun Young Park
Publikováno v:
Current Molecular Pharmacology. 15:570-581
Background and Objective: Colorectal cancer (CRC) is the fourth leading cause of cancer- related death globally, with a high incidence rate in economically fast-growing countries. Sphingosine- 1-phosphate (S1P) is a bioactive lipid mediator that play