Zobrazeno 1 - 10
of 460
pro vyhledávání: '"Tamura A"'
Autor:
Kenji Wakai, Tetsuya Mizoue, Shiori Tanaka, Tetsuhisa Kitamura, Kotaro Ozasa, Shuhei Nomura, Keitaro Matsuo, Shizuka Sasazuki, Michihiro Muto, Hidekazu Suzuki, Taichi Shimazu, Tomio Nakayama, Yingsong Lin, Norie Sawada, Motoki Iwasaki, Tetsuya Otani, Keitaro Tanaka, Isao Oze, Atsuko Sadakane, Shoichiro Tsugane, Sarah Krull Abe, Mariko Naito, Eiko Saito, Yoshikazu Nishino, Yoshitaka Tsubono, Chisato Nagata, Yumi Sugawara, Keiko Wada, Ayami Ono, Taiki Yamaji, Takashi Tamura, Ichiro Tsuji, Hidemi Ito, Yuri Kitamura, Hadrien Charvat, Akiko Tamakoshi, Mai Utada, Mamami Inoue
Publikováno v:
Cancer Science
The association between alcohol intake and stomach cancer risk remains controversial. We undertook a pooled analysis of data from six large‐scale Japanese cohort studies with 256 478 participants on this topic. Alcohol intake as ethanol was estimat
Autor:
Kenji Tamura, Kazuki Sudo, Hiroshi Yoshida, Takayuki Kinoshita, Tatsunori Shimoi, Kan Yonemori, Jun Hashimoto, Takahiro Fukuda, Yasuhiro Fujiwara, Masayuki Yoshida, Mayu Yunokawa, Chikako Shimizu, Akihiko Shimomura, Emi Noguchi, Tomoyasu Kato
Publikováno v:
BMC Cancer, Vol 21, Iss 1, Pp 1-7 (2021)
BMC Cancer
BMC Cancer
Background The V-Akt murine thymoma viral oncogene (AKT) 1 (E17K) is a subfamily of serine/threonine protein kinases that affects the survival, proliferation, and invasion of cancer cells. The clinicopathological features and frequencies in Asian pop
Autor:
Li Yuan Bai, Yee Chao, Narikazu Boku, Taroh Satoh, Hyun Cheol Chung, Masahiro Tsuda, Won Ki Kang, Yoon-Koo Kang, Jae Yong Cho, Jen-Shi Chen, Ken Kato, Jong Gwang Kim, Yasuo Hamamoto, Keiko Minashi, Keun Wook Lee, Kun-Huei Yeh, Hiroki Sameshima, Keisho Chin, Sang Cheul Oh, Li-Tzong Chen, Kei Muro, Takaki Yoshikawa, Min Hee Ryu, Takao Tamura, Do Youn Oh, Satoshi Morita
Publikováno v:
Gastric Cancer
Background The phase 3 ATTRACTION-2 study demonstrated that nivolumab monotherapy was superior to placebo for patients with pretreated advanced gastric or gastroesophageal junction cancer, but early progression of tumors in some patients was of conce
Autor:
Kuniko Sunami, Tetsu Hayashida, Kazuto Nishio, Shinji Kohsaka, Ichiro Kinoshita, Hiroyuki Uetake, Kenji Tamura, Koshi Mimori, Hideaki Takahashi, Shinichi Toyooka, Noboru Yamamoto, Hideaki Bando, Masayuki Takeda, Keigo Komine, Katsuya Tsuchihara, Yoichi Naito, Yasushi Yatabe
Publikováno v:
Cancer Science
Comprehensive genomic profiling (CGP) is being increasingly used for the routine clinical management of solid cancers. In July 2018, the use of tumor tissue‐based CGP assays became available for all solid cancers under the universal health insuranc
Tertiary lymphoid structures show infiltration of effective tumor‐resident T cells in gastric cancer
Autor:
Yoshihito Yamakoshi, Yuichiro Miki, Mami Yoshii, Sota Deguchi, Shugo Suzuki, Takuya Mori, Tatsuro Tamura, Kazuya Muguruma, Takahiro Toyokawa, Shigeru Lee, Masaichi Ohira, Hideki Wanibuchi, Hiroaki Tanaka
Publikováno v:
Cancer Science
Several studies have reported that tissue‐resident memory T cells (TRM cells) or tertiary lymphoid structures (TLSs) are associated with a good prognosis. The aim of this study was to clarify the association of TRM cells and TLSs in the tumor immun
Autor:
Yoshiaki Maru, Makiko Enaka, Kentaro Fushimi, Akihiro Suzuki, Shingo Kato, Tomohiko Tamura, Takuma Higurashi, Noritoshi Kobayashi, Atsushi Nakajima, Yuichiro Yabuki, Yoshitaka Hippo, Daisuke Kurotaki, Sho Hasegawa, Masato Yoneda, Tetsuya Matsuura
Publikováno v:
Oncogenesis, Vol 10, Iss 4, Pp 1-13 (2021)
Oncogenesis
Oncogenesis
Genetically engineered mice (GEM) are the gold standard for cancer modeling. However, strict recapitulation of stepwise carcinogenesis from a single tumor-initiating epithelial cell among genetically intact cells in adults is not feasible with the cu
Autor:
Lin Zhang, Yali Liu, Shanu Modi, Sara A. Hurvitz, Yeon Hee Park, Javad Shahidi, Cristina Saura, Junji Tsurutani, Seock-Ah Im, Hiroji Iwata, Yoshinori Ito, Ian E. Krop, Keun Seok Lee, Neelima Denduluri, Kenji Tamura, Toshinari Yamashita, Joohyuk Sohn, Eriko Tokunaga, Caleb Lee, José Baselga, Christophe Perrin, Sung Bae Kim, Kenjiro Aogi, Fabrice Andre, Javier Cortes, Antoine Yver
Publikováno v:
Cancer Research. 81:PD3-06
Background Trastuzumab deruxtecan (T-DXd, DS-8201) is an antibody-drug conjugate with a HER2 antibody, tetrapeptide-based cleavable linker, and a novel topoisomerase I inhibitor payload. DESTINY-Breast01 (NCT03248492) is an open-label, international,
Autor:
Taira Naruto, Satoshi Morita, Koichiro Tsugawa, Masato Takahashi, Hiroji Iwata, Yoshie Hasegawa, Masakazu Toi, Tetsuhiro Yoshinami, Shigehira Saji, Norikazu Masuda, Hiroshi Tada, Kenji Tamura, Takashi Yamanaka, Takayuki Ueno, Fumikata Hara, Shinji Ohno, Yutaka Yamamoto, Toshimi Takano, Tatsuya Toyama, Masahiro Kashiwaba
Publikováno v:
Cancer Research. 81:PD3-11
Background: Patients (pts) with HER2-positive locallyadvanced/metastatic breast cancer (LA/MBC) previously treated with pertuzumab(P)-containing regimens have few therapeutic options. The efficacy of Pre-treatment combined with trastuzumab (T)+chemot
Autor:
Yasutomo Nakai, Motokiyo Komiyama, Naohisa Kusakabe, Motohide Uemura, Mikio Sugimoto, Satoshi Anai, Keita Tamura, Nobuo Shinohara, Kosuke Ueda, Ken Tanaka, Keita Minami, Kojiro Ohba, Tetsuya Shindo, Michinobu Ozawa, Naoki Kohei, Toshihiro Suzuki, Takahiro Osawa, Hideaki Miyake, Ario Takeuchi, Akira Yokomizo
Publikováno v:
Japanese Journal of Clinical Oncology. 51:810-818
Purpose To externally validate the utility of the albumin, C-reactive protein and lactate dehydrogenase model to predict the overall survival of previously treated metastatic renal cell carcinoma patients. Patients and methods The ability of the albu
Publikováno v:
Anticancer Research. 40:5229-5235
Background/aim The prolactin receptor (PRLR) is implicated in the tumorigenesis of breast and prostate cancers where it drives cell proliferation, survival, and migration. LFA102 is a humanized monoclonal antibody against PRLR with promising preclini