Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Chunai Gong"'
Publikováno v:
Journal of Biomaterials Applications. 36:1317-1331
Resistance to apoptosis is a key mechanism underlying how cancer cells evade tumor therapy. Autophagy can prevent anticancer drug-induced apoptosis and promote tumor resistance. The purpose of this study was to improve the sensitivity and efficacy of
Publikováno v:
Journal of Nanobiotechnology
Journal of Nanobiotechnology, Vol 19, Iss 1, Pp 1-23 (2021)
Journal of Nanobiotechnology, Vol 19, Iss 1, Pp 1-23 (2021)
Background Biomimetic nanotechnology-based RNA interference (RNAi) has been successful in improving theranostic efficacy in malignant tumors. Its integration with hybrid biomimetic membranes made of natural cell membranes fused with liposomal membran
Publikováno v:
Journal of Nanobiotechnology
Journal of Nanobiotechnology, Vol 19, Iss 1, Pp 1-12 (2021)
Journal of Nanobiotechnology, Vol 19, Iss 1, Pp 1-12 (2021)
Graphical Abstract In addition to early detection, early diagnosis, and early surgery, it is of great significance to use new strategies for the treatment of hepatocellular carcinoma (HCC). Studies showed that the combination of sorafenib (SFN) and t
Publikováno v:
Journal of Nanobiotechnology
Journal of Nanobiotechnology, Vol 19, Iss 1, Pp 1-20 (2021)
Journal of Nanobiotechnology, Vol 19, Iss 1, Pp 1-20 (2021)
The combination of an immuno-metabolic adjuvant and immune checkpoint inhibitors holds great promise for effective suppression of tumor growth and invasion. In this study, a pH-responsive co-delivery platform was developed for metformin (Met), a know
Autor:
Chunai Gong, Yan Wu, Lu Han, Yujie Wang, Rong Wang, Xiaoyan Yu, Yongfang Yuan, Benming You, Shen Gao
Publikováno v:
Journal of Nanobiotechnology
Journal of Nanobiotechnology, Vol 18, Iss 1, Pp 1-17 (2020)
Journal of Nanobiotechnology, Vol 18, Iss 1, Pp 1-17 (2020)
Cell membrane- covered drug-delivery nanoplatforms have been garnering attention because of their enhanced bio-interfacing capabilities that originate from source cells. In this top-down technique, nanoparticles (NPs) are covered by various membrane
Autor:
Tai Zongguang, Yuan Gao, Jiyong Liu, Zheng Cai, Shen Gao, Guorui Li, Wenjun Jiang, Lei Qiang, Chunai Gong
Publikováno v:
Journal of Nanobiotechnology, Vol 17, Iss 1, Pp 1-15 (2019)
Journal of Nanobiotechnology
Journal of Nanobiotechnology
Background Macrophages with tumor-tropic migratory properties can serve as a cellular carrier to enhance the efficacy of anti neoplastic agents. However, limited drug loading (DL) and insufficient drug release at the tumor site remain the main obstac
Autor:
Gu Fenfen, Qingming Xia, Shen Gao, Chuling Hu, Yuan Gao, Lijuan Zhang, Chunai Gong, Lei Qiang, Chong Yao
Publikováno v:
Journal of controlled release : official journal of the Controlled Release Society. 266
The lysosomal degradation pathway of autophagy has a crucial role in protecting cancer cells from multiple endogenous and exogenous stresses, particularly during the pathogenesis of cancer. Accordingly, agents that inhibit autophagy may have broad th