Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Christos Vaklavas"'
Publikováno v:
Translational Oncology, Vol 13, Iss 2, Pp 452-470 (2020)
Translational Oncology
Translational Oncology
Gene expression is extensively and dynamically modulated at the level of translation. How cancer cells prioritize the translation of certain mRNAs over others from a pool of competing mRNAs remains an open question. Here, we analyze translation in ce
Publikováno v:
Cancer Research. 77:P1-05
Although our understanding of transcriptional dysregulation in cancer has expanded dramatically over the recent years, comparatively little is known about dysregulation in gene expression at the translational level. Yet, gene expression is extensivel
Publikováno v:
Frontiers in Oncology, Vol 7 (2017)
Frontiers in Oncology
Frontiers in Oncology
Although transcript levels have been traditionally used as a surrogate measure of gene expression, it is increasingly recognized that the latter is extensively and dynamically modulated at the level of translation (messenger RNA to protein). Over the
Publikováno v:
Pharmacology & Therapeutics. 130:177-190
Cardiac glycosides, statins, β-blockers, angiotensin-I converting enzyme inhibitors (ACEIs), and angiotensin II type 1 receptor blockers (ARBs) are widely used cardiovascular medications with pleiotropic properties. Many of these medications have be
Publikováno v:
Antibody-Drug Conjugates and Immunotoxins ISBN: 9781461454557
The development of monoclonal antibodies as cancer therapeutic agents has improved the outlook for many patients as evidenced by the number of such drugs that have been approved for oncologic indications [1]. Monoclonal antibodies allow selective kil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::75d8472c8fa323447fc7bedff9c3f44e
https://doi.org/10.1007/978-1-4614-5456-4_12
https://doi.org/10.1007/978-1-4614-5456-4_12
Autor:
William E. Grizzle, Richard J. Whitley, Maaike Everts, Christos Vaklavas, Joseph A. Maddry, Miranda Nebane-Akah, Lynn Rasmussen, Scott W. Blume, Andra R. Frost, E. Lucile White, Cecil R. Stockard, Zheng Meng, Sharon Samuel, Kurt R. Zinn
Publikováno v:
Cancer Research. 72:1816-1816
Many genes involved in the control of cell proliferation and survival, i.e. those most important to cancer biology, are now known to be regulated specifically at the translational (RNA to protein) level. An intriguing translation-regulatory element i