Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Challa S. S. R. Kumar"'
Autor:
P. L. Clasen, Mikko Haataja, Josef Hormes, Gigi Galiana, Carola Leuschner, J. Meng, Challa S. S. R. Kumar, Wole Soboyejo, Jun Fan, J. Zhou, Martin P. Harmer, S Ma, Christopher J. Kiely, T. Otiti, Warren S. Warren, Rosa T. Branca, A. C. Beye
Publikováno v:
Materials Science and Engineering: C. 29:1467-1479
This paper shows that superparamagnetic iron oxide nanoparticles (SPIONs) conjugated to luteinizing hormone releasing hormone (LHRH) (LHRH–SPIONs), can be used to target breast cancer cells. They also act as contrast enhancement agents during the m
Autor:
Challa S. S. R. Kumar, Michelle O. Fletcher Claville, Achuthan C. Raghavamenon, Faruq Mohammad, Rao M. Uppu
Publikováno v:
Nanotechnology Reviews, Vol 3, Iss 4, Pp 389-400 (2014)
The hyperthermia-induced cytotoxicity of gold-coated SPIONs conjugated to LHRH (SPIONs@Au-LHRH) has been studied in LHRH-receptor overexpressing murine GT1-7 hypothalamic neurons (noncancerous) and human LNCaP cells (cancerous). In the absence of an
Autor:
Challa S. S. R. Kumar, Rosa T. Branca, Zackary I. Cleveland, Warren S. Warren, Boma Fubara, Bastiaan Driehuys, Carola Leuschner, Robert R. Maronpot
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 107(8)
Early and specific detection of metastatic cancer cells in the lung (the most common organ targeted by metastases) could significantly improve cancer treatment outcomes. However, the most widespread lung imaging methods use ionizing radiation and hav
Autor:
Josef Hormes, Jikou Zhou, Wole Soboyejo, William Hansel, Carola Leuschner, Challa S. S. R. Kumar
Publikováno v:
Breast cancer research and treatment. 99(2)
Targeted delivery of superparamagnetic iron oxide nanoparticles (SPIONs) could facilitate their accumulation in metastatic cancer cells in peripheral tissues, lymph nodes and bones and enhance the sensitivity of magnetic resonance imaging (MRI). The
Publikováno v:
Biomaterials. 27(9)
In this study, the sub-cellular accumulation of superparamagnetic iron oxide nanoparticles (SPIONs) in breast tumors and peripheral organs were investigated. MNPs were conjugated with luteinizing hormone releasing hormone (LHRH), whose receptors are