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pro vyhledávání: '"Emi Ota Machida"'
Autor:
Kornel E. Schuebel, Stephen B. Baylin, Yang Y. Yu, Steven A. Belinsky, Christine A. Stidley, Mathewos Tessema, Emi Ota Machida
Publikováno v:
Carcinogenesis. 30:1132-1138
Aberrant promoter hypermethylation is one of the major mechanisms in carcinogenesis and some critical growth regulatory genes have shown commonality in methylation across solid tumors. Twenty-six genes, 14 identified through methylation in colon and
Autor:
William H. Westra, James G. Herman, Emi Ota Machida, Stephen B. Baylin, Julien D.F. Licchesi, Craig M. Hooker
Publikováno v:
Carcinogenesis. 29(5)
Background: Atypical adenomatous hyperplasia (AAH) is now recognized as a precursor lesion from which lung adenocarcinomas arise and thus represents an ideal target for studying the early genetic and epigenetic alterations associated with lung tumori