Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Zhi-Qiang Xiao"'
Autor:
Zhi-Qiang Xiao, Jiao-Yang Li, Wei Huang, Juan Feng, Yan-Hong Zhou, Xin-Hui Li, Hong-Mei Yi, Shan-Shan Lu, Jin-Feng Zhu, Ta Xiao, Hong Yi
Publikováno v:
Cancer Letters. 444:162-174
Our phosphoproteomics identified that phosphorylation of EphA2 at serine 897 (pS897-EphA2) was significantly upregulated in the high metastatic nasopharyngeal carcinoma (NPC) cells relative to non-metastatic NPC cells. However, the role and underlyin
Publikováno v:
Journal of Hematology & Oncology
Journal of Hematology & Oncology, Vol 13, Iss 1, Pp 1-17 (2020)
Journal of Hematology & Oncology, Vol 13, Iss 1, Pp 1-17 (2020)
Eph receptors and the corresponding Eph receptor-interacting (ephrin) ligands jointly constitute a critical cell signaling network that has multiple functions. The tyrosine kinase EphA2, which belongs to the family of Eph receptors, is highly produce
Autor:
Facai Cui, Zhi-Qiang Xiao, Kun Wang, Bin Yi, Ya Tao, Shiyang Qiu, Lepan Zhu, Manlin Xiang, Yunlai Liang, Lu Long, Yuan Jiang, Qiong Wu, Zhen Chen
Publikováno v:
Oncotarget
// Ya Tao 1,* , Kun Wang 1,* , Zhen Chen 1 , Lu Long 1 , Qiong Wu 1 , Facai Cui 1 , Lepan Zhu 1 , Manlin Xiang 1 , Yuan Jiang 1,2 , Yunlai Liang 1 , Shiyang Qiu 1 , Zhiqiang Xiao 3 and Bin Yi 1 1 Department of Clinical Laboratory, Xiangya Hospital, C
Autor:
Zheng-Zheng Yu, Shan-Shan Lu, Wei Zhu, Wei Huang, Guo-Hui Nie, Zhi-Qiang Xiao, Yaoyun Tang, Xueping Feng, Juan Feng, Jiao-Yang Li, Ta Xiao, Hong Yi, Song Gao, Song-Qing Fan
Publikováno v:
SSRN Electronic Journal.
ANXA1 and EphA2 play a crucial role in cancer. Here, we report that ANXA1 competes with Cbl for binding EphA2 and increases its stability by inhibiting Cbl-mediated EphA2 ubiquitination degradation in nasopharyngeal carcinoma (NPC), leading to the en
Autor:
Lu Long, Zhi-Qiang Xiao, Shiyang Qiu, Lepan Zhu, Yunlai Liang, Bin Yi, Ya Tao, Qiong Wu, Manlin Xiang, Zhen Chen, Kun Wang, Facai Cui
Publikováno v:
Oncotarget
// Zhen Chen 1,* , Lu Long 1,* , Kun Wang 1 , Facai Cui 1 , Lepan Zhu 1 , Ya Tao 1 , Qiong Wu 1 , Manlin Xiang 1 , Yunlai Liang 1 , Shiyang Qiu 1 , Zhiqiang Xiao 2 and Bin Yi 1 1 Department of Clinical Laboratory, Xiangya Hospital, Central South Univ
Publikováno v:
Journal of Proteomics. 74:2642-2649
A major problem in chemotherapy of cancer patients is drug resistance as well as unpredictable response to treatment. During chemotherapy, multiple alterations of genetics and epigenetics that contribute to chemoresistance take place, eventually impa
Autor:
Zhi-Qiang Xiao, Yi Sun, Cui Li, Xueping Feng, Maoyu Li, Yan Xu, Peng-Fei Zhang, Hui-Ying Shi, Gu-Qing Zeng, Zhuchu Chen, Jia-Quan Qu, Xun-Xun Wan, Xin-Hui Li, Hong Yi
Publikováno v:
Journal of Proteomics. 74:2723-2733
Radiotherapy is the primary treatment for nasopharyngeal cancer (NPC), and p53 is closely associated with the radiosensitivity of cancer, but the molecular mechanisms of p53-mediated radioresponse in NPC remains unclear. We previously established NPC
Autor:
Yongmei Ouyang, Yanhui Yu, Zhimin He, Zhuchu Chen, Renkui Ding, Fang Peng, Zhi-Qiang Xiao, Guopei Zheng
Publikováno v:
Journal of Cancer Research and Clinical Oncology. 136:1477-1488
This study aimed to explore the mechanism of multi-drug resistance (MDR) in 5-fluorouracil (5-FU)-induced breast cancer cell MCF-7.MCF-7 cells were exposed in stepwise escalating concentration of 5-FU to develop the resistant cell line, MCF-7/5-FU. B
Autor:
Feng Li, Fang Yang, Zhi-Qiang Xiao, Zhuchu Chen, Dan-juan Li, Xiu-zhi Zhang, Zhefeng Xiao, Maoyu Li, Cui Li
Publikováno v:
Cancer Science. 100:2396-2401
There is currently substantial interest in the identification of human tumor antigens for the diagnosis and immunotherapy of cancer. In our previous study, secretion character and up-regulation of triosephosphate isomerase were observed in lung squam
Autor:
Qiu-Yan He, Yuan-Yuan Wang, Jiao-Yang Li, Hong-Mei Yi, Li Yuan, Juan Feng, Xu Ye, Zhi-Qiang Xiao, Li-Na Li, Ta Xiao, Jing-Feng Zhu, Hong Yi, Jia-Quan Qu, Shan-Shan Lu
Publikováno v:
Molecular cancer therapeutics. 14(11)
Radioresistance poses a major challenge in nasopharyngeal carcinoma (NPC) treatment, but little is known about how miRNA (miR) regulates this phenomenon. In this study, we investigated the function and mechanism of miR-203 in NPC radioresistance, one