Zobrazeno 1 - 10
of 134
pro vyhledávání: '"M. O'Reilly"'
Autor:
Chander Singh Digwal, Peter J. Allen, Thomas A. Neubert, Swathi Merugu, Eileen M. O'Reilly, Wanyan Wang, Lon Yin L. Chan, Vinagolu K. Rajasekhar, Suhasini Joshi, Tony Taldone, Nagavarakishore Pillarsetty, Olivera Grbovic-Huezo, Erica DaGama Gomes, Maeve A. Lowery, Srinivasa Gandu, Anna Rodina, Stephen D. Ginsberg, Gabriela Chiosis, Vlad Miclea, Elisa de Stanchina, Laura H. Tang, Palak Panchal, Chris Sander, Lisa Shrestha, Kenneth H. Yu, Chao Xu, Steven D. Leach, Hediye Erdjument-Bromage, Marissa Mattar, Pengrong Yan, Radu I Peter, John H. Healey, Adriana D. Corben, Justina Almodovar, Sahil Sharma, William R. Jarnagin, Yelena Y. Janjigian, Salma Buddaseth, Tai Wang, Askan Gokce
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-20 (2021)
Communications Biology
Communications Biology
Cancer cell plasticity due to the dynamic architecture of interactome networks provides a vexing outlet for therapy evasion. Here, through chemical biology approaches for systems level exploration of protein connectivity changes applied to pancreatic
Publikováno v:
Cancer Biology & Therapy. 22:532-536
Metastatic pancreatic adenocarcinoma (PDAC) is a rapidly lethal disease, with less than half of patients surviving 12 months, and 5-year survival approximately 3%. These outcomes are in large part ...
Autor:
Sorbarikor Piawah, Kimmie Ng, Alan P. Venook, Federico Innocenti, Charles D. Blanke, Eileen M. O'Reilly, Marla Lipsyc-Sharf, Jeffrey A. Meyerhardt, Andrew B. Nixon, Katherine Van Loon, Tiffany M Bainter, Richard M. Goldberg, Chao Ma, Heinz-Josef Lenz, Robert J. Mayer, Sui Zhang, Fang-Shu Ou, Nadine Jackson McCleary, C. Fuchs, Donna Niedzwiecki, I-Wen Chang
Publikováno v:
J Natl Cancer Inst
BackgroundThe incidence of young-onset colorectal cancer (yoCRC) is increasing. It is unknown if there are survival differences between young and older patients with metastatic colorectal cancer (mCRC).MethodsWe studied the association of age with su
Autor:
Paul Glare, Justin M Lebenthal, Andrew Chung Yang, Junting Zheng, Andrew S. Epstein, Eileen M. O'Reilly
Publikováno v:
Cancer
Background The Memorial Sloan Kettering Prognostic Score (MPS), a composite of the neutrophil-lymphocyte ratio (NLR) and albumin, is an objective prognostic tool created as a more readily available alternative to the Glasgow Prognostic Score. A prior
Autor:
Olivia Mason, Patricia Fitzpatrick, Elizabeth J. Ryan, Glen A. Doherty, Diarmuid O'Donoghue, Garret Cullen, Hugh Mulcahy, Katie N Hughes, Mary B. Codd, Therese Mooney, Sara McNally, Susanne M. O’Reilly
Publikováno v:
Frontline Gastroenterol
Background/objectiveColorectal cancer (CRC) screening is proven to reduce CRC-related mortality. Faecal immunochemical testing (FIT)-positive clients in the Irish National CRC Screening Programme underwent colonoscopy. Round 1 uptake was 40.2%. We so
Publikováno v:
Cancer Medicine, Vol 9, Iss 13, Pp 4572-4580 (2020)
Cancer Medicine
Cancer Medicine
Introduction Evidence‐based recommendations on duration of multiagent systemic therapy for LAPC are lacking. Herein, we assess the impact of duration of combination systemic therapy on survival of patients with LAPC. Methods The National Cancer Dat
Autor:
Michael F. Berger, Mark E. Robson, Maeve A. Lowery, Eileen M. O'Reilly, Yelena Kemel, Zsofia K. Stadler, Marc Ladanyi, Diana Mandelker, Liying Zhang, Ghassan K. Abou-Alfa, Michele Ly, David B. Solit, Imane El Dika, Hannah Maynard, Emmett Jordan
Publikováno v:
Cancer
BACKGROUND With limited information on germline mutations in biliary tract cancers, this study performed somatic and germline testing for patients at Memorial Sloan Kettering Cancer Center with known biliary tract carcinoma with the aim of determinin
Autor:
Joseph A. O'Donoghue, Wolfgang A. Weber, Rebecca Teng, Paul W. Maffuid, Jorge A. Carrasquillo, Christian Lohrmann, Eileen M. O'Reilly, Jason S. Lewis, Neeta Pandit-Taskar, Shutian Ruan, Serge K. Lyashchenko, Wolfgang W. Scholz
Publikováno v:
Clin Cancer Res
Purpose: In patients with cancer who have an abnormal biomarker finding, the source of the biomarker in the bloodstream must be located for confirmation of diagnosis, staging, and therapy planning. We evaluated if immuno-PET with the radiolabeled hig
Autor:
Kimmie Ng, Charles D. Blanke, Robert J. Mayer, Eileen M. O'Reilly, Brendan J. Guercio, Kaori Sato, Jeffrey A. Meyerhardt, Bert H. O'Neil, Alan P. Venook, Fang-Shu Ou, Howard S. Hochster, Sui Zhang, James N. Atkins, Blase N. Polite, Richard M. Goldberg, Erin L. Van Blarigan, Charles S. Fuchs, Donna Niedzwiecki, James Edward Shaw, Federico Innocenti, Heinz-Josef Lenz
Publikováno v:
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, vol 37, iss 29
PURPOSE Regular physical activity is associated with reduced risk of recurrence and mortality in patients with nonmetastatic colorectal cancer. Its influence on patients with advanced/metastatic colorectal cancer (mCRC) has been largely unexplored. P
Autor:
Eric Van Cutsem, Teresa Macarulla, Pascal Hammel, Albrecht Stenzinger, Thomas Seufferlein, Jean-Luc Van Laethem, Eileen M. O'Reilly, Alexander Kleger, Pieter-Jan Cuyle, Joaquim Bellmunt, Estelle Cauchin, Lukas Perkhofer, Tamara Matysiak-Budnik, Johann Gout, Alica K Beutel, Talia Golan
Publikováno v:
Cancers (Basel), 13 (17
Cancers, Vol 13, Iss 4259, p 4259 (2021)
Scientia
Cancers
Cancers, Vol 13, Iss 4259, p 4259 (2021)
Scientia
Cancers
Impaired DNA damage repair (DDR) is increasingly recognised as a hallmark in pancreatic ductal adenocarcinoma (PDAC). It is estimated that around 14% of human PDACs harbour mutations in genes involved in DDR, including, amongst others, BRCA1/2, PALB2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c064448577161c2189c34b51c136bfa