Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Lucia Knopfová"'
Autor:
Sára Lenárt, Šárka Šimečková, Radek Fedr, Zuzana Kahounová, Jan Bouchal, Petr Beneš, Gvantsa Kharaishvili, Lucia Binó, Eva Slabáková, Milan Král, Tereza Kučírková, Ján Remšík, Lucia Knopfová, Karel Souček, Ximena Maria Muresan
Publikováno v:
Carcinogenesis. 39(11)
The cell surface glycoprotein Trop-2 is commonly overexpressed in carcinomas and represents an exceptional antigen for targeted therapy. Here, we provide evidence that surface Trop-2 expression is functionally connected with an epithelial phenotype i
Autor:
Vojtech Adam, Petr Babula, Monika Holubová, Martina Raudenská, Markéta Sztalmachová, Michal Masarik, Jaromír Gumulec, Jan Balvan, Hana Polanska, René Kizek, Lucia Knopfová, Kristyna Hudcova
Publikováno v:
International Journal of Oncology. 46:1810-1818
Breast cancer patients negative for the nuclear oestrogen receptor α have a particularly poor prognosis. Therefore, the 4T1 cell line (considered as a triple-negative model) was chosen to induce malignancy in mice. The aim of the present study was t
Autor:
Pavel Kopel, Lukas Nejdl, Lucia Knopfová, Markéta Sztalmachová, Martina Raudenská, Marie Stiborová, Michal Masarik, Jana Vlachova, René Kizek, Michaela Fojtu, Vojtech Adam, Petr Babula, Anna Skotakova, Sylvie Skalickova, Jaromír Gumulec
Publikováno v:
International Journal of Molecular Sciences, Vol 15, Iss 12, Pp 22960-22977 (2014)
International Journal of Molecular Sciences. 2014, vol. 15, issue 12, p. 22960-22977.
International Journal of Molecular Sciences
Volume 15
Issue 12
Pages 22960-22977
International Journal of Molecular Sciences. 2014, vol. 15, issue 12, p. 22960-22977.
International Journal of Molecular Sciences
Volume 15
Issue 12
Pages 22960-22977
Doxorubicin is an effective chemotherapeutic drug, however, its toxicity is a significant limitation in therapy. Encapsulation of doxorubicin inside liposomes or ferritin cages decreases cardiotoxicity while maintaining anticancer potency. We synthes
Publikováno v:
Klinicka onkologie. 27:S22-S27
Migration and invasiveness are phenotypic characteristics of cells that contribute to physiological processes, such as wound healing or embryogenesis and they are involved in serious pathological processes, namely in tumor cell metastasis. Availabili
Autor:
Jan Šmarda, Lucia Knopfová
Publikováno v:
Experimental and Therapeutic Medicine. 1:257-264
Increased production of the pro-inflammatory enzyme cyclooxygenase-2 (Cox-2) and altered expression and activity of peroxisome proliferator-activated receptor γ (PPARγ) have been observed in many malignancies. Both the PPARγ ligands and the Cox-2
Publikováno v:
Pathology. 46:S76
Transcription factor c-Myb is required for maintenance of progenitor cells in colon epithelium. Deregulation of c-Myb is frequently linked with tumorigenesis. For colorectal carcinomas, high c-Myb expression denotes tumors with poor prognosis. Oxidat
Autor:
Jaromir Gumulec, Michaela Fojtu, Martina Raudenska, Marketa Sztalmachova, Anna Skotakova, Jana Vlachova, Sylvie Skalickova, Lukas Nejdl, Pavel Kopel, Lucia Knopfova, Vojtech Adam, Rene Kizek, Marie Stiborova, Petr Babula, Michal Masarik
Publikováno v:
International Journal of Molecular Sciences, Vol 15, Iss 12, Pp 22960-22977 (2014)
Doxorubicin is an effective chemotherapeutic drug, however, its toxicity is a significant limitation in therapy. Encapsulation of doxorubicin inside liposomes or ferritin cages decreases cardiotoxicity while maintaining anticancer potency. We synthes
Externí odkaz:
https://doaj.org/article/83fba333ebf64f6ca510cf93e401855f