Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Eudocia Q. Lee"'
Autor:
Eudocia Q. Lee
Publikováno v:
CONTINUUM: Lifelong Learning in Neurology. 26:1629-1645
Purpose of review Neurologic complications in patients with cancer can significantly impact morbidity and mortality. Although these complications can be seen in patients without cancer as well, the purpose of this review is to highlight how the prese
Autor:
Rifaquat Rahman, Minesh P. Mehta, David A. Reardon, Louis B. Nabors, Timothy F. Cloughesy, John Sampson, Evanthia Galanis, Susan M. Chang, Roger Stupp, Mustafa Khasraw, Eudocia Q. Lee, Shawn Kothari, Manmeet S Ahluwalia, Stephen J Bagley, Patrick Y. Wen, Stuart A. Grossman, Simon Khagi, Erik P. Sulman, Michael Weller, Gavin P. Dunn
Publikováno v:
Clin Cancer Res
Clinical cancer research : an official journal of the American Association for Cancer Research, vol 28, iss 4
Clinical cancer research : an official journal of the American Association for Cancer Research, vol 28, iss 4
Therapeutic advances for glioblastoma have been minimal over the past 2 decades. In light of the multitude of recent phase III trials that have failed to meet their primary endpoints following promising preclinical and early-phase programs, a Society
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::612f47b9746bfe62bd08464f5d6d027d
https://europepmc.org/articles/PMC9044253/
https://europepmc.org/articles/PMC9044253/
Autor:
Florence Coulet, Jill S. Barnholtz-Sloan, Marc Sanson, Adam Boynton, Aniket Shetty, Yvonne Y. Li, Tracy T. Batchelor, Marine Giry, Garrett M. Frampton, Alexandre Carpentier, Peter J. Park, Franck Bielle, Eudocia Q. Lee, Khê Hoang-Xuan, Jean-Yves Delattre, Leon Taquet, Philippe Cornu, Erell Guillerm, Andrew D. Cherniack, Liam F. Spurr, Robert E. Jones, Mehdi Touat, Rameen Beroukhim, Patrick Y. Wen, J. Bryan Iorgulescu, David Meredith, Kristine Pelton, Caroline Dehais, Radwa Sharaf, Sandro Santagata, Alex Duval, Kenin Qian, Nadia Younan, Florence Laigle-Donadey, Patricia Ho, J Ricardo McFaline-Figueroa, Juliana Bonardi, Mary Jane Lim-Fat, David A. Reardon, Capucine Baldini, Naomi Currimjee, Shakti H. Ramkissoon, Caroline Houillier, Katie Pricola Fehnel, Seth Malinowski, Dimitri Psimaras, Cristina Birzu, Charlotte Bellamy, Isidro Cortes-Ciriano, Keith L. Ligon, Jack Geduldig, Karima Mokhtari, Maite Verreault, Lee A. Albacker, Pratiti Bandopadhayay, Bertrand Mathon, Susan N. Chi, E. Antonio Chiocca, Agusti Alentorn, Dean Pavlick, Frank Dubois, Sangita Pal, Samy Ammari, Brian M. Alexander, Arnab Chakravarti, Azra H. Ligon, Sanda Alexandrescu, Ahmed Idbaih, Frédéric Beuvon, Lakshmi Nayak, Laurent Capelle, Aurélien Marabelle, Daphne A. Haas-Kogan, Raymond Y. Huang, Craig L. Bohrson, Wenya Linda Bi, Ruben Ferrer-Luna, Kin-Hoe Chow
Publikováno v:
Nature
A high tumour mutational burden (hypermutation) is observed in some gliomas1–5; however, the mechanisms by which hypermutation develops and whether it predicts the response to immunotherapy are poorly understood. Here we comprehensively analyse the
Autor:
Patrick Y. Wen, Jordi Rodon, Timothy F. Cloughesy, Benjamin M. Ellingson, Lars Mueller, Alan G. Olivero, Timothy R. Wilson, Xuyang Lu, Alexandre Coimbra, Kari M. Morrissey, Eudocia Q. Lee, Elizabeth R. Gerstner
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research, vol 26, iss 8
Purpose: GDC-0084 is an oral, brain-penetrant small-molecule inhibitor of PI3K and mTOR. A first-in-human, phase I study was conducted in patients with recurrent high-grade glioma. Patients and Methods: GDC-0084 was administered orally, once daily, t
Autor:
Eudocia Q. Lee
Publikováno v:
Current Neurology and Neuroscience Reports. 21
Purpose of review To review the neurologic complications of systemic anti-cancer therapies and radiation therapy. Recent findings Although many of the newer systemic therapies have more favorable side effect profiles than traditional cytotoxic chemot
Autor:
Viktor A. Adalsteinsson, Jackson Stocking, Megha Subramanian, Alex K. Shalek, Samuel Markson, Ivanna Bihun, Joana L. Mora, Andrew W. Navia, Scott L. Carter, Priscilla K. Brastianos, Daniel P. Cahill, Nancy Wang, Eudocia Q. Lee, Christopher Alvarez-Breckenridge, Kellie E. Kolb, Sanjay M. Prakadan, Marc H. Wadsworth, Denisse Rotem, Jeffrey W. Miller, Ryan J. Sullivan, Robert H. Klein, Michael White, Benjamin M. Kuter, Alexander Kaplan, Ugonma Chukwueke, Albert E. Kim, Mia Bertalan, Brian A. Shaw, Naema Nayyar
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
Nature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
Leptomeningeal disease (LMD) is a devastating complication of solid tumor malignancies, with dire prognosis and no effective systemic treatment options. Over the past decade, the incidence of LMD has steadily increased due to therapeutics that have e
Autor:
Chitkala Kalidas, W. K. Alfred Yung, Andrew B. Lassman, John de Groot, David Arons, Joseph C. Kvedar, Mustafa Khasraw, Susan M. Chang, Clair Meehan, Lee H. Schwamm, Mary Welch, Jeffrey A. Bacha, Erik Bloomquist, Solmaz Sahebjam, Wendy Selig, Patrick Y. Wen, Evanthia Galanis, Vinay K. Puduvalli, Amy Barone, Gelareh Zadeh, Islam Hassan, Eudocia Q. Lee, Sharon Tamir
Publikováno v:
Neuro-Oncology
On July 24, 2020, a workshop sponsored by the National Brain Tumor Society was held on innovating brain tumor clinical trials based on lessons learned from the COVID-19 experience. Various stakeholders from the brain tumor community participated incl
Autor:
Sydney Whorral, Wenya Linda Bi, Lakshmi Nayak, David Meredith, Marie Allen, Mehdi Touat, Bryan Iorgulescu, Tracy T. Batchelor, Rifaquat Rahman, Jayne Vogelzang, William Pisano, Eudocia Q. Lee, E. Antonio Chiocca, Gilbert Youssef, Mary Jane Lim-Fat, David A. Reardon, Eleanor Woodward, Ugonma Chukwueke, Patrick Y. Wen, Jose Mcfaline-Figueroa, Keith L. Ligon, Sandro Santagata, Rameen Beroukhim
Publikováno v:
Neuro Oncol
BACKGROUND Comprehensive next generation sequencing (NGS) is available through many academic institutions and commercial entities, and is incorporated in practice guidelines for glioblastoma (GBM). We retrospective evaluated the practice patterns and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ffa97ef5cdf5df4268af1121c87664d6
https://europepmc.org/articles/PMC7650887/
https://europepmc.org/articles/PMC7650887/
Autor:
Patrick Y. Wen, Eudocia Q. Lee
Publikováno v:
ESMO Open
ESMO Open, Vol 5, Iss Suppl 4 (2020)
ESMO Open, Vol 5, Iss Suppl 4 (2020)
The study population within phase III clinical trials leading to approval of new cancer agents should ideally more closely mirror the population who will ultimately receive these agents. Although the number of females participating in clinical trials
Autor:
Patrick Roth, Jill S. Barnholtz-Sloan, Marc Sanson, Jonathan Tsang, Tracy T. Batchelor, Ingo K. Mellinghoff, Minesh P. Mehta, Kenneth Aldape, Martin J B Taphoorn, Floris P. Barthel, Ranjit S. Bindra, Emilie Le Rhun, David Nathanson, Matthias Preusser, David A. Reardon, Michael Platten, Susan M. Chang, Brian M. Alexander, Andreas von Deimling, Martin J. van den Bent, Andrew B. Lassman, Craig Horbinski, Gelareh Zadeh, Roel G.W. Verhaak, E. Antonio Chiocca, Evanthia Galanis, Susan C Short, Eudocia Q. Lee, Patrick Y. Wen, John DeGroot, Raymond Y. Huang, Michael Weller, Mark R. Gilbert, Joerg C. Tonn, Wolfgang Wick, Monika E. Hegi, David Schiff, Michael Lim, Giuseppe Minniti, Timothy F. Cloughesy
Publikováno v:
Neuro Oncol
Neuro-oncology, vol 22, iss 8
Neuro-Oncology
Neuro-Oncology, Oxford University Press (OUP), 2020, 22 (8), pp.1073-1113. ⟨10.1093/neuonc/noaa106⟩
Neuro-Oncology, 22(8), 1073-1113. OXFORD UNIV PRESS INC
Neuro-Oncology, 2020, 22 (8), pp.1073-1113. ⟨10.1093/neuonc/noaa106⟩
Neuro-Oncology, 22(8), 1073-1113. Oxford University Press
Neuro-oncology, vol 22, iss 8
Neuro-Oncology
Neuro-Oncology, Oxford University Press (OUP), 2020, 22 (8), pp.1073-1113. ⟨10.1093/neuonc/noaa106⟩
Neuro-Oncology, 22(8), 1073-1113. OXFORD UNIV PRESS INC
Neuro-Oncology, 2020, 22 (8), pp.1073-1113. ⟨10.1093/neuonc/noaa106⟩
Neuro-Oncology, 22(8), 1073-1113. Oxford University Press
Glioblastomas are the most common form of malignant primary brain tumor and an important cause of morbidity and mortality. In recent years there have been important advances in understanding the molecular pathogenesis and biology of these tumors, but
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5974a0e3a1762a5ebbce520823ecdb62
https://europepmc.org/articles/PMC7594557/
https://europepmc.org/articles/PMC7594557/